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Tavaborole

go.drugbank.com/drugs/DB09041
Approved

Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme require...

  1. Pathway

    Tavaborole Drug Metabolism

    smpdb.ca/view/SMP0130662
    Metabolic

    Tavaborole passes through the liver and is then excreted from the body mainly through the kidney. … Tavaborole is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Tavaborole
  2. Pathway

    Tavaborole Action Pathway

    smpdb.ca/view/SMP0125844
    Drug action

    Tavaborole is an antifungal agent used to treat onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

    Drugs: Adenosine phosphate · Leucine · ATP · Pyrophosphoric acid · Tavaborole
  3. Indication

    Onychomycosis of the Toenails caused by Trichophyton rubrum

    go.drugbank.com/conditions/DBCOND0146862
    Drugs: Tavaborole
  4. Indication

    Onychomycosis of the Toenails caused by Trichophyton mentagrophytes

    go.drugbank.com/conditions/DBCOND0146863
    Drugs: Tavaborole