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  1. Pathway

    Valacyclovir Action Pathway

    smpdb.ca/view/SMP0125888
    Drug action

    Aciclovir is transported from the liver into the blood via a drug transporter, then into the effected cells. … Valacyclovir is rapidly and almost completely converted in man to aciclovir and valine, likely by the enzyme valacyclovir hydrolase.

    Drugs: Valine · Valaciclovir · Acyclovir · Magnesium cation
    Enzymes: Valacyclovir hydrolase
  2. Pathway

    Aldosterone from Steroidogenesis

    smpdb.ca/view/SMP0121126
    Physiological

    Angiotensin II from the circulation binds to receptors on the zona glomerulosa cell membrane, activating the G protein and triggering a signaling cascade. … From there, cholesterol undergoes a series of reactions in both the mitochondrion and the smooth endoplasmic reticulum (steroidogenesis) where it finally becomes aldosterone.

    Drugs: NADH · Progesterone · Mesoheme · Cholesterol · Corticosterone