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Displaying all 9 results
  1. Target

    Chemotaxis protein CheY

    go.drugbank.com/bio_entities/BE0002023
    TargetEscherichia coli (strain K12)

    In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar … Overexpression of CheY in association with MotA and MotB improves motility of a ycgR disruption, suggesting there is an interaction (direct or indirect) between the c-di-GMP-binding flagellar brake protein

    Polypeptides: Chemotaxis protein CheY
  2. Target

    Chemotaxis protein CheA

    go.drugbank.com/bio_entities/BE0001431
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).

    Polypeptides: Chemotaxis protein CheA
  3. Target

    Methyl-accepting chemotaxis protein II

    go.drugbank.com/bio_entities/BE0001434
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Receptor for the attractant L-aspartate and related amino and dicarboxylic acids. Tar mediates taxis away from the repellents cobalt and nickel. Unlike in E.coli tar, it does not mediate maltose taxis.

    Synonyms: cheM
  4. Target

    Nitric oxide synthase oxygenase

    go.drugbank.com/bio_entities/BE0001483
    TargetStaphylococcus aureus (strain MW2)

    Catalyzes the production of nitric oxide.

    Synonyms: SANOS
  5. Target

    Cholinesterase

    go.drugbank.com/bio_entities/BE0002180
    TargetEnzymeHumans

    Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters

    Synonyms: CHE1
  6. Target

    Serine--tRNA ligase, cytoplasmic

    go.drugbank.com/bio_entities/BE0000063
    TargetHumans

    Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:26433229, PubMed:282...

    Synonyms: SARS
  7. Target

    Aldo-keto reductase family 1 member C4

    go.drugbank.com/bio_entities/BE0000438
    TargetCarrierEnzymeHumans

    Cytosolic aldo-keto reductase that catalyzes NADPH-dependent reduction of ketosteroids to hydroxysteroids. Displays broad substrate specificity with distinct positional and stereochemistry, primarily generating 3alpha/beta-, 17beta- and ...

    Synonyms: CHDR
  8. Target

    20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)

    go.drugbank.com/bio_entities/BE0009795
    EnzymeHumans and other mammals

    Cytosolic aldo-keto reductase that catalyzes NADPH-dependent reduction of ketosteroids to hydroxysteroids. Displays broad substrate specificity with distinct positional and stereochemistry, primarily generating 20alpha-hydroxysteroids, b...

    Synonyms: CHDR
  9. Target

    Aldo-keto reductase family

    go.drugbank.com/bio_entities/BE0009802
    EnzymeHumans

    Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity). Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro) (PubMed:12604216, PubMed:15118078)

    Synonyms: CHDR