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Displaying results 1 - 10 of 403 in total
  1. Target

    Melanoma antigen preferentially expressed in tumors

    go.drugbank.com/bio_entities/BE0010493
    TargetHumans

    In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin … Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation (PubMed:21822215, PubMed:26138980

    Polypeptides: Melanoma antigen preferentially expressed in tumors
  2. Target

    Membrane protein involved in aromatic hydrocarbon degradation

    go.drugbank.com/bio_entities/BE0003979
    TargetPseudomonas putida (strain F1 / ATCC 700007)

    Polypeptides: Membrane protein involved in aromatic hydrocarbon degradation
  3. Target

    Chitinase A

    go.drugbank.com/bio_entities/BE0001649
    TargetSerratia marcescens

    Polypeptides: Chitinase A
  4. Target

    Gyrase A

    go.drugbank.com/bio_entities/BE0008384
    TargetMycobacterium tuberculosis

    Polypeptides: Gyrase A
  5. Target

    Cyclin A

    go.drugbank.com/bio_entities/BE0009669
    Target

  6. Target

    Proenkephalin-A

    go.drugbank.com/bio_entities/BE0010659
    TargetHumans

    They play a role in a number of physiologic functions, including pain perception and responses to stress

    Polypeptides: Proenkephalin-A
  7. Target

    Apolipoprotein(a)

    go.drugbank.com/bio_entities/BE0001283
    TargetHumans

    Lp(a) may be a ligand for megalin/Gp 330 … Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.

    Polypeptides: Apolipoprotein(a)Synonyms: Lp(a), Apo(a)
  8. Target

    Exotoxin A

    go.drugbank.com/bio_entities/BE0001869
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis (PubMed:18276581, PubMed:2170123). Ha...

    Polypeptides: Exotoxin A
  9. Target

    Endoglucanase A

    go.drugbank.com/bio_entities/BE0002017
    TargetClostridium thermocellum

    This enzyme catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Polypeptides: Endoglucanase ASynonyms: Cellulase A
  10. Target

    Pepsin A

    go.drugbank.com/bio_entities/BE0004062
    TargetSIV-mac

    Polypeptides: Pepsin A