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Cytochrome c oxidase subunit 7A1, mitochondrial
go.drugbank.com/bio_entities/BE0003996TargetHumansComponent of the mitochondrial respiratory complex IV (CIV, also named cytochrome c oxidase complex), the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation (By similarity). The CIV complex i...
Synonyms: Cytochrome c oxidase subunit VIIa-H, Cytochrome c oxidase subunit VIIa-MCytochrome c oxidase subunit 6A2, mitochondrial
go.drugbank.com/bio_entities/BE0003994TargetHumansElectrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit
Synonyms: COX VIa-M, Cytochrome c oxidase subunit VIA-muscleInactive phospholipase C-like protein 1
go.drugbank.com/bio_entities/BE0001081TargetHumansInvolved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A recepto...
Synonyms: Phospholipase C-related but catalytically inactive proteinV-type immunoglobulin domain-containing suppressor of T-cell activation
go.drugbank.com/bio_entities/BE0010797TargetHumansImmunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666...
Synonyms: VISTAImmunoglobulin heavy constant alpha 2
go.drugbank.com/bio_entities/BE0004610TargetHumansConstant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglo...
Synonyms: Ig alpha-2 chain C region BUTImmunoglobulin heavy constant alpha 1
go.drugbank.com/bio_entities/BE0005097TargetHumansConstant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglo...
Synonyms: Ig alpha-1 chain C region BURPlatelet-activating factor acetylhydrolase
go.drugbank.com/bio_entities/BE0002409TargetHumansLipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response (PubMed:10066756, PubMed:16371369, PubMed:17090529, PubMed:2040620, PubMed:7700381, PubMed:...
Synonyms: Group-VIIA phospholipase A2Immunoglobulin heavy variable 3-30
go.drugbank.com/bio_entities/BE0004312TargetHumansV region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocy...
Synonyms: Ig heavy chain V-III region BUR