Search

Displaying all 6 results
  1. Pathway

    Nebivolol Predicted Metabolism Pathway

    smpdb.ca/view/SMP0174667
    Metabolic

    Metabolites of sildenafil are predicted with biotransformer.

    Drugs: Mesoheme · Nebivolol
  2. Pathway

    Nebivolol Action Pathway

    smpdb.ca/view/SMP0000366
    Drug action

    Nebivolol (also known as Bystolic or Nebivololum) is a β1-receptor blocker (selective β1-receptor antagonist) that can bind and inhibit Beta-1 adrenergic receptor in muscule and heart. … Nebivolol can also prevent release of renin (a hormone from kidneys), which can result in reduced level of constriction of blood vessels.

    Drugs: ATP · Potassium cation · Calcium · Nebivolol
  3. Pathway

    Nebivolol Action Pathway (New)

    smpdb.ca/view/SMP0126215
    Drug action

    In bronchial and vascular smooth muscle, nebivolol can compete with epinephrine for beta-2 adrenergic receptors. … Nebivolol also reduce sympathetic activity and is used to treat hypertension, angina, migraine headaches, and hypertrophic subaortic stenosis.

    Drugs: ATP · Calcium · Nebivolol
  4. Pathway

    Hydrochlorothiazide Drug Metabolism

    smpdb.ca/view/SMP0130739
    Metabolic

    Hydrochlorothiazide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Hydrochlorothiazide passes through the liver and is then excreted from the body mainly through the kid...

    Drugs: Hydrochlorothiazide
  5. Pathway

    Hydrochlorothiazide Action Pathway

    smpdb.ca/view/SMP0000100
    Drug action

    Hydroflumethiazide (also known as Esidrix or Oretic) is an organic compound that used for diuretic. It can inhibit the solute carrier family 12 member 3 (also known as sodium-chloride symporter) in the nephron to prevent water reabsorpti...

    Drugs: Cysteine · Hydrochlorothiazide · Potassium cation · Urea
  6. Pathway

    Hydrochlorothiazide Diuretic Action Pathway

    smpdb.ca/view/SMP0122688
    Drug action

    Hydrochlorothiazide is an oral diuretic drug that acts in the kidney, specifically in the distal convoluted tubule of the nephron. It is used to treat conditions such as hypertension, heart failure, severe resistant edema, nephrogenic di...

    Drugs: Hydrochlorothiazide · Potassium cation · Calcium