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Displaying results 1 - 10 of 11 in total
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Oxytocin

go.drugbank.com/drugs/DB00107
ApprovedInvestigationalVet approved

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist na...

  1. Drug

    Carbetocin

    go.drugbank.com/drugs/DB01282
    ApprovedInvestigational

    It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.

    Categories: Oxytocin and AnaloguesSynonyms: 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin
  2. Drug

    Atosiban

    go.drugbank.com/drugs/DB09059
    ApprovedInvestigational

    Atosiban is an inhibitor of the hormones oxytocin and vasopressin. It is used intravenously to halt premature labor.

  3. Drug

    Gemeprost

    go.drugbank.com/drugs/DB08964
    ApprovedWithdrawn

    Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mif...

  4. Drug

    Vasopressin

    go.drugbank.com/drugs/DB00067
    ApprovedInvestigational

    [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids.

  5. Drug

    Midomafetamine

    go.drugbank.com/drugs/DB01454
    IllicitInvestigational

    An N-substituted amphetamine analog. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems. It is commonly referred to as MDMA or ecstasy. It is a widely abused drug...

  6. Drug

    Cligosiban

    go.drugbank.com/drugs/DB20573
    Experimental

    The usage of the INN stem '-siban' in the name indicates that Cligosiban is a oxytocin antagonist. Cligosiban has a monoisotopic molecular weight of 419.12 Da.

  7. Drug

    Cyclic GMP

    go.drugbank.com/drugs/DB02315
    Experimental

    Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)

  8. Drug

    Barusiban

    go.drugbank.com/drugs/DB12292
    Investigational

    Barusiban has been used in trials studying the treatment of Infertility and In Vitro Fertilisation (IVF) Treatment.

    Categories: Receptors, Oxytocin, antagonists & inhibitors
  9. Drug

    Methylergometrine

    go.drugbank.com/drugs/DB00353
    ApprovedInvestigational

    A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)

    Categories: methylergometrine and oxytocin