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Human immunoglobulin G

go.drugbank.com/drugs/DB00028
ApprovedInvestigational

Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody s...

  1. Drug

    Recombinant human CD4 immunoglobulin G

    go.drugbank.com/drugs/DB17812
    Investigational

    Synonyms: Recombinant human CD4 immunoglobulin G, Recombinant CD4 immunoglobulin G
  2. Drug

    Antilymphocyte immunoglobulin (horse)

    go.drugbank.com/drugs/DB09312
    ApprovedInvestigational

    It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. … Equine anti-thymocyte globulin is composed of purified gamma globulin containing primarily IgG against human thymus lymphocytes.

    Categories: Immunoglobulin G, ImmunoglobulinsSynonyms: Antilymphocyte immunoglobulin (horse), e-ATG
  3. Drug

    Antithymocyte immunoglobulin (rabbit)

    go.drugbank.com/drugs/DB00098
    ApprovedInvestigational

    Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells. … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients.

    Synonyms: Anti-human thymocyte immunoglobulin, rabbit, Rabbit anti-human thymocyte immunoglobulinInternational brands: ATG-Fresenius S
  4. Drug

    Tetanus immune globulin, human

    go.drugbank.com/drugs/DB11604
    ApprovedInvestigational

    Tetanus Immune Globulin is manufactured from human plasma [FDA Label]. It contains antibodies against tetanus toxoid and is primarily used as prophylaxis against tetanus in wounded patients.

    Categories: Human Tetanus Immune Globulins, ImmunoglobulinsSynonyms: Tetanus immunoglobulin (human), Tetanus immunoglobulin
  5. Drug

    Hepatitis B immune globulin

    go.drugbank.com/drugs/DB05276
    ApprovedInvestigational

    Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. … Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines.

    Categories: Human Immunoglobulin, hepatitis B immunoglobulinSynonyms: Human hepatitis B immunoglobulin, Human hepatitis-B immunoglobulin
  6. Drug

    Human cytomegalovirus immune globulin

    go.drugbank.com/drugs/DB13886
    ApprovedInvestigational

    Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). … It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label].

    Categories: Human Immunoglobulin G, Immunoglobulin GSynonyms: Human cytomegalovirus immunoglobulin, Cytomegalovirus immunoglobulin
  7. Drug

    Human Rho(D) immune globulin

    go.drugbank.com/drugs/DB11597
    Approved

    Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). … Immune globullin was purified via ion-exchange chromatography method and prepared from pools of human plasma, where the donors are Rho (D)-negative donors who have been immunized with Rho(D)-positive RBCs

    Categories: Human Immunoglobulin G, anti-D (rh) immunoglobulinSynonyms: Human anti-D immunoglobulin, Anti-D (RH) immunoglobulin (human)
  8. Drug

    Anthrax immune globulin human

    go.drugbank.com/drugs/DB09057
    ApprovedInvestigational

    Anthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. … It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified.

    Synonyms: Anthrax immunoglobulin (human), Anthrax immune globulin humanCategories: Human Immunoglobulin, Immunoglobulins
  9. Drug

    Infliximab

    go.drugbank.com/drugs/DB00065
    ApprovedInvestigational

    Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. … Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in chronic inflammatory diseases [A31469].

    Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERCategories: Immunoglobulins