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AV-101
go.drugbank.com/drugs/DB12878InvestigationalAV-101 has been used in trials studying the treatment of Neuropathic Pain.
AV-COVID-19
go.drugbank.com/drugs/DB15802InvestigationalAV-COVID-19 is a vaccine composed of autologous dendritic cells loaded with SARS-CoV-2 antigens and with or without Granulocyte-macrophage colony-stimulating factor (GM-CSF). … As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.
Florbenazine F-18
go.drugbank.com/drugs/DB14945InvestigationalFlorbenazine F-18 is under investigation in clinical trial NCT01515384 (A Trial of 18F-AV-133 Positron Emission Tomography (PET)).
Synonyms: 18F-AV-133Modafinil
go.drugbank.com/drugs/DB00745ApprovedInvestigationalModafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. … Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesProducts: Provigil, PROVIGILJNJ-27548547
go.drugbank.com/drugs/DB15372InvestigationalJNJ-27548547 is under investigation in clinical trial NCT01705002 (Intravenously Administered Pegylated Liposomal Mitomycin-C Lipid-based Prodrug (PROMITIL) in Cancer Patients With Solid Tumors.).
Synonyms: PROMITILBimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigationalBimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. … [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug
Mixtures: GANFORT PF, GANFORT PF Eye DropsCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesD-glucose
go.drugbank.com/drugs/DB01914ApprovedInvestigationalVet approvedL-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation.
Mixtures: DIANEAL PD-2 CON DEXTROSA AL 1.5%., DIANEAL PD-2 CON DEXTROSA AL 1.5%.Categories: Compounds used in a research, industrial, or household settingAluminum chloride
go.drugbank.com/drugs/DB11081ApprovedInvestigationalIt may also be found in over-the-counter as an antiperspirant or prescription products as an antihemorrhagic agent. … In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15%, calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012].
Categories: Compounds used in a research, industrial, or household settingProducts: Duradry PM, Frenna AC