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Displaying results 1 - 10 of 8547 in total
  1. Drug

    Trazodone

    go.drugbank.com/drugs/DB00656
    ApprovedInvestigational

    Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. … [T646] Trazodone acts on various receptors, including certain histamine, serotonin, and adrenergic receptors, distinguishing it from other antidepressants that cover a narrow range of neurotransmitters

    Synonyms: Trazodone, TrazodonaSalts: Trazodone hydrochloride
  2. Pathway

    Trazodone H1-Antihistamine Blood Vessel Constriction Action Pathway

    smpdb.ca/view/SMP0175051
    Drug action

    Trazodone is a drug that sometimes acts as a H1-antihistamine. … Trazodone inhibits the H1 histamine receptor on blood vessel endothelial cells.

    Drugs: Arginine · Citrulline · Sapropterin · Nitric Oxide · Trazodone · Calcium +4 more
  3. Pathway

    Trazodone H1 Antihistamine Neurological Sleep Action Pathway

    smpdb.ca/view/SMP0145430
    Drug action

    Trazodone inhibits the H1 histamine receptor, preventing the depolarization of the post-synaptic neuron. … Trazodone is an ethanolamine class H1 antihistamine used to treat insomnia and allergy symptoms such as hay fever and hives.

    Drugs: Pyridoxal phosphate · Histidine · Trazodone · Calcium
  4. Pathway

    Trazodone H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0175143
    Drug action

    Trazodone is a drug that sometimes acts as a H1-antihistamine.

    Drugs: Trazodone · Calcium
  5. Pathway

    Trazodone H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0174959
    Drug action

    Trazodone is a drug that sometimes acts as a H1-antihistamine. … Trazodone also inhibits the H1 histamine receptor on bronchiole smooth muscle myocytes.

    Drugs: Trazodone · Calcium · Magnesium cation
  6. Drug

    Nivolumab

    go.drugbank.com/drugs/DB09035
    ApprovedInvestigational

    [A35203] It was developed by Bristol Myers Squibb.[L12129] Nivolumab was granted FDA approval on 22 December 2014. … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.

    Products: NIVOLUMAB BMS CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/ML, OPDIVO®100MG/10ML
  7. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

    Mixtures: Bal-Care DHA, Triveen-PRx RNFProducts: C Rola Tab 100mg, Vitamin C Tab 100mg
  8. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    [L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection. … [A229853, A229923] Temozomolide as an adjunct to radiotherapy followed by maintenance dosing remains the standard of care for both Glioblastoma and refractory anaplastic astrocytoma.

    Synonyms: 3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamideProducts: TEMAZ® 100MG, TRIPZOL® 100MG
  9. Drug

    Largemouth bass

    go.drugbank.com/drugs/DB10976
    Approved

    Largemouth bass allergenic extract is used in allergenic testing.

    Synonyms: Largemouth bassProducts: Black Bass
  10. Drug

    Lamivudine

    go.drugbank.com/drugs/DB00709
    ApprovedInvestigational

    A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).

    Mixtures: COMBIVIR 150MG/300MG, COMBIVIR 150MG/300MGProducts: ZEFFIX 100MG, LAMIVIR 100MG