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Displaying drugs 1026 - 1050 of 15551 in total
Approved
Matched Mixtures name: … BEXSERO 0,5 ML İM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET 2 İĞNELİ …
Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity, which is...
Approved
Matched Iupac: … 2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide …
Matched Description: … Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of ... [L32853] An extended-release granule formulation was subsequently granted approval in March 2021 for ... [L32853] Mirabegron first received FDA approval in 2012, under the brand name Myrbetriq, for the treatment …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Adrenergic beta-3 Receptor Agonists ... Selective Beta 3-adrenergic Agonists …
Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.
Approved
Investigational
Matched Description: … Pegaptanib is a polynucleotide aptamer. ... Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces …
Matched Categories: … Vascular Endothelial Growth Factor A
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Iupac: … [(1R,2S,5R)-7-oxo-2-[(piperidin-4-yl)carbamoyl]-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Description: … Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam]. ... [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... product RecarbrioⓇ in July 2019. …
Matched Categories: … MATE 2 Substrates ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use ... Heterocyclic Compounds, 2-Ring …
Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as remifentanil, are designed to be metabolically fragile and thus susceptible to rapid...
Approved
Investigational
Matched Iupac: … methyl 3-[(7S)-12-bromo-3-methyl-9-(pyridin-2-yl)-2,5,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14), …
Matched Description: … [A214857] These "soft drugs" are useful in the context of surgical procedures, wherein a rapid onset/ ... A214857] Remimazolam was the first "soft" benzodiazepine analog to be developed[A214862] and was approved for ... use by the FDA in July 2020 under the brand name Byfavo. …
Matched Salts cas: … 1001415-66-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Prostate-specific membrane antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA (Schulke et al., PNAS 100:12590, 2003)....
Approved
Investigational
Matched Description: … antigen (PSMA) is an ∼100 kDa transmembrane glycoprotein that is abundantly and preferentially expressed in ... prostate cancer, including recurrent and hormone-refractory cases. rsPSMA Vaccine is a subunit vaccine ... based on a novel rsPSMA protein that represents the entire extracellular domain of PSMA (Schulke et …
Streptococcus pneumoniae type 15b capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 15b of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … Streptococcus pneumoniae type 15b capsular polysaccharide antigen is a vaccine that contains highly purified ... It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche …
Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated. A total of...
Approved
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoic acid …
Matched Description: … One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated ... With two exceptions, all complications occurred during injection of the right coronary artery. ... Metrizoic acid is a molecule used as a contrast medium. …
Matched Salts cas: … 20828-80-2
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Iupac: … 3-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido …
Matched Description: … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast …
Matched Salts cas: … 59018-13-2
Matched Categories: … Compounds used in a research, industrial, or household setting …
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Iupac: … (68Ga)gallium(3+) 3-(3-{[(2-{[(5-{2-[(5-{[(5S)-5-carboxy-5-({[(1S)-1,3-dicarboxypropyl]carbamoyl}amino ... )pentyl]carbamoyl}pentyl)carbamoyl]ethyl}-2-hydroxyphenyl)methyl](carboxylatomethyl)amino}ethyl)(carboxylatomethyl …
Matched Description: … [A225396] In nearly all prostate cancers, malignant cells express a transmembrane protein called prostate-specific ... In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended Ga-68 gozetotide ... [L44682] In Octer 2022, Ga-68 PSMA-11 was approved by Health Canada for diagnostic use in men with prostate …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically derived from DB12604. The structure of plazomicin was established via appending hydroxylaminobutyric acid to DB12604 at position 1 and 2-hydroxyethyl group at position 6' . It was designed to evade all clinically relevant aminoglycoside-modifying enzymes, which contribute to the main...
Approved
Investigational
Matched Iupac: … -2H-pyran-2-yl]oxy}-2-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-3-hydroxycyclohexyl ... (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro ... ]-2-hydroxybutanamide …
Matched Description: … On June 28th, 2018, plazomicin sulfate was approved by the FDA for use in adult patients for the treatment ... Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically ... of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position 1 and 2- …
Matched Categories: … MATE 2 Inhibitors ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin …
Matched Description: … [A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in ... Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole …
Matched Mixtures name: … Ketoconazole 2% / Salicylic Acid 2% ... Ketoconazole 2% / Niacinamide 4% ... Hydrocortisone 2.5% / Ketoconazole 2% …
Matched Categories: … Antifungals for Topical Use ... Antimycotics for Systemic Use ... Antiinfectives for Systemic Use ... Antifungals for Dermatological Use …
Matched Products: … Nizoral A-D ... A-BE LOTION ... KETORAL 400 MG VAJİNAL SUPOZİTUVAR, 3 ADET …
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Iupac: … methyl[(3R)-3-(2-methylphenoxy)-3-phenylpropyl]amine …
Matched Description: … and amphetamines, have a high potential for abuse and dependence. ... Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention ... role for the glutamatergic system in the pathophysiology of ADHD. …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Potassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. Potassium is most commonly used in flares and automobile airbags . The use of potassium perchlorate as a component in sealing gaskets for food containers...
Approved
Investigational
Matched Description: … The use of potassium perchlorate as a component in sealing gaskets for food containers has been revoked ... The therapeutic use of potassium perchlorate in thyroid disorders has been ceased due to a high risk ... for developing aplastic anemia and nephrotic syndrome [L2364]. …
Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity . It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and antifungal properties. Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone. As a long-term stabilizer...
Approved
Investigational
Vet approved
Matched Iupac: … 1,1,1-trichloro-2-methylpropan-2-ol …
Matched Description: … Chlorobutanol is a common detergent preservative in eye drops and other ophthalmic therapeutic formulations ... As a long-term stabilizer of multi-ingredient preparations, chlorobutanol is normally used at a concentration ... It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and …
Matched Mixtures name: … DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Doxacurium chloride is a long-acting, nondepolarizing skeletal muscle relaxant for intravenous administration.
Approved
Matched Iupac: … 6,7,8-trimethoxy-2-methyl-2-(3-{[4-oxo-4-(3-{6,7,8-trimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl ... ]-1,2,3,4-tetrahydroisoquinolin-2-ium-2-yl}propoxy)butanoyl]oxy}propyl)-1-[(3,4,5-trimethoxyphenyl)methyl ... ]-1,2,3,4-tetrahydroisoquinolin-2-ium …
Matched Description: … Doxacurium chloride is a long-acting, nondepolarizing skeletal muscle relaxant for intravenous administration …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Matched International brands: … A Di Xian ... A Gan Ding …
Matched Iupac: … [({[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}({[(2,2-dimethylpropanoyl)oxy]methoxy})phosphoryl)oxy]methyl …
Matched Description: … Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Iupac: … 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one …
Matched Description: … [A190525] Luckily, several treatment options for psychotic disorders have been introduced to market since ... [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower ... the realization of chlorpromazine's antipsychotic properties in 1952. …
Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Matched Description: … [L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant ... [L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113] ... it to be used in different types of formulations. …
Matched Salts cas: … 3529-04-2
Matched Categories: … Compounds used in a research, industrial, or household setting …
Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Description: … Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein ... Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... syndromes, including familial cold auto-inflammatory syndrome (FCAS) and Muckle-Wells Syndrome (MWS), in
Matched Categories: … Agents reducing cytokine levels
Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … for the general population. ... Pure cresol is a mixture of ortho-, meta-, and para- isomers. ... Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. …
Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...
Approved
Matched Iupac: … 13-chloro-2-{1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene}-4-azatricyclo[9.4.0.0^{3,8}]pentadeca ... -1(15),3(8),4,6,11,13-hexaene …
Matched Description: … It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for ... used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria ... Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is …
Matched Categories: … Antihistamines for Systemic Use …
Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina. A transdermal preparation was approved for use in Japan in January 2006.
Approved
Matched Iupac: … 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid …
Matched Description: … A transdermal preparation was approved for use in Japan in January 2006. ... Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. ... , and as Oxeno in Argentina. …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Description: … ] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid]). ... [A252827] Sodium thiosulfate is approved for the treatment of acute cyanide poisoning[L310,L43332,A252832 ... Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Matched Iupac: … 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide …
Matched Description: … membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar ... A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac …
Displaying drugs 1026 - 1050 of 15551 in total