Displaying drugs 10976 - 11000 of 12185 in total
SNS01-T
SNS01-T is a gene therapy nanoparticle. It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.
Investigational
Matched Description: … SNS01-T is a gene therapy nanoparticle. ... It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets …
BMN-351
BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to exon 51 of dystrophin pre-mRNA. It is under investigation for the treatment of Duchenne Muscular Dystrophy (DMD).
Investigational
Matched Description: … BMN-351 is a fully modified 18-mer oligonucleotide with a TEG modification at its 5' end that binds to …
Denufosol
Denufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial. A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in...
Investigational
Matched Description: … showed a lack of improvement in lung function for cystic fibrosis patients taking denufosol. ... used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a ... A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial …
Plinabulin
Investigational
CGC-11047
CGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis.
Investigational
Matched Description: … CGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis. …
MDR-101
MDR-101 is a CD34+ hematopoietic stem and progenitor cells with CD3+ T-cells
Investigational
Matched Description: … MDR-101 is a CD34+ hematopoietic stem and progenitor cells with CD3+ T-cells …
ISTH0036
ISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 mRNA
Investigational
Matched Description: … ISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 …
ISA101b
ISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.
Investigational
Matched Description: … ISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins. …
IR502
IR502 (Zorcell) is a potential treatment for psoriasis.
Investigational
Matched Description: … IR502 (Zorcell) is a potential treatment for psoriasis. …
WIN-54954
WIN-54954 is a broad-spectrum antipicornavirus drug.
Experimental
Matched Description: … WIN-54954 is a broad-spectrum antipicornavirus drug. …
Sacubitrilat
A metabolite of LCZ696 with neprilysin inhibitory activity.
Experimental
Matched Description: … A metabolite of LCZ696 with neprilysin inhibitory activity. …
Indatraline
Indatraline is a nonselective monoamine reuptake inhibitor.
Investigational
Matched Description: … Indatraline is a nonselective monoamine reuptake inhibitor.[A253022] …
8-chlorotheophylline
8-Chlorotheophylline is a stimulant drug of the xanthine chemical class, with physiological effects similar to caffeine. Its main use is in combination with Diphenhydramine as the antiemetic drug Dimenhydrinate. The stimulant properties of 8-chlorotheophylline are thought to ward off the drowsiness caused by diphenhydramine's anti-histamine activity in the central nervous...
Experimental
Matched Description: … 8-Chlorotheophylline is a stimulant drug of the xanthine chemical class, with physiological effects similar ... Because adenosine causes a decrease in neuronal firing, blockade of the adenosine receptor causes the ... diphenhydramine's anti-histamine activity in the central nervous system.
8-chlorotheophylline produces a …
Nacubactam
Nacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection).
Investigational
Matched Description: … of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection). ... Nacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics …
Ladarixin
Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).
Investigational
Matched Description: … Type 1 Diabetes and a Low Residual Β-Cell Function). ... Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset …
TAK-611
TAK-611, formerly known as SHP611, is a recombinant human arylsulfatase A. First developed by Takeda, it is being investigated for the treatment of metachromatic leukodystrophy.
Investigational
Matched Description: … TAK-611, formerly known as SHP611, is a recombinant human arylsulfatase A. …
MDX-1379
MDX-1379 vaccine consists of two gp100 melanoma peptides. This drug is underinvestigation to treat malignant melanoma.
Investigational
Depatuxizumab mafodotin
Depatuxizumab/Denintuzumab mafodotin has been used in trials studying the treatment of Lymphoma, Gliosarcoma, Glioblastoma, Malignant Glioma, Squamous Cell Tumors, and Glioblastoma Multiforme.
Investigational
Velusetrag
Velusetrag has been used in trials studying the treatment of Gastroparesis and Alzheimer's Disease. It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance. Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research...
Investigational
Matched Description: … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. ... Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research …
Tertomotide
Tertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study of LTX-315 as adjunct to tertomotide in Patients Following Curative Surgery for Carcinoma). It is a peptide vaccine that activates the immune system so that it recognizes and kills cancer cells. It is being developed by Pharmexa...
Investigational
Matched Description: … It is being developed by Pharmexa A/S. ... Tertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study ... It is a peptide vaccine that activates the immune system so that it recognizes and kills cancer cells …
Farnesol
A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in vertebrates. It has a delicate odor and is used in perfumery. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th...
Experimental
Matched Description: … It has a delicate odor and is used in perfumery. ... A colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. …
(1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene
(1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene is a solid. This compound belongs to the naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. Known drug targets of (1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene include naphthalene 1,2-dioxygenase subunit beta and naphthalene 1,2-dioxygenase subunit alpha.
Experimental
Matched Description: … (1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene is a solid. ... These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. …
RO7284755
RO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein. RO7284755 is under investigation in clinical trial NCT04303858 (A Study to Evaluate Safety and Anti-tumor Activity of RO7284755 Alone or in Combination With Atezolizumab in Participants With Advanced And/or Metastatic Solid Tumors).
Investigational
Matched Description: … RO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein ... RO7284755 is under investigation in clinical trial NCT04303858 (A Study to Evaluate Safety and Anti-tumor …
PPI-1040
Investigational
Displaying drugs 10976 - 11000 of 12185 in total