Displaying drugs 11076 - 11100 of 11952 in total
GMX1777
GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa...
Investigational
Matched Description: … GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic ... In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a …
PAC-113
PAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva. In vitro studies demonstrate that it has potent anti-fungal activity against the Candida albicans, including drug-resistant HIV patient isolates. PAC-113 is targeting oral...
Investigational
Matched Description: … It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found …
Orgotein
Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage. Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide radical into either the less damaging hydrogen peroxide or molecular oxygen. Hydrogen peroxide can be degraded by catalase. The antioxidant...
Investigational
Vet approved
Matched Description: … A notable exception is Lactobacillus plantarum. ... Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage …
Metharbital
Metharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Withdrawn
Matched Description: … Metharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott …
Elocalcitol
Elocalcitol is a calcitriol analog for inhibition of prostate cell growth; in phase II clinical trial in patients with benign prostate hyperplasia (4/2004).
Investigational
Matched Description: … Elocalcitol is a calcitriol analog for inhibition of prostate cell growth; in phase II clinical trial …
SUVN-G3031
SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects).
Investigational
Matched Description: … SUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability …
Pimodivir
Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Participants).
Investigational
Matched Description: … Pimodivir is under investigation in clinical trial NCT02658825 (A Study to Evaluate the Effect of JNJ …
Palladium Pd-103
Palladium Pd-103 is under investigation in clinical trial NCT00247312 (Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A Prospective Randomized Trial).
Investigational
Matched Description: … investigation in clinical trial NCT00247312 (Pd-103 Dose De-Escalation for Early Stage Prostate Cancer: A …
Domagrozumab
Domagrozumab is under investigation in clinical trial NCT01616277 (A Phase 1 Study To Evaluate The Safety And Tolerability Of PF-06252616 In Healthy Subjects).
Investigational
Matched Description: … Domagrozumab is under investigation in clinical trial NCT01616277 (A Phase 1 Study To Evaluate The Safety …
CB-1158
CB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors).
Investigational
Matched Description: … CB-1158 is under investigation in clinical trial NCT03910530 (A Study of INCMGA00012, INCB001158, and …
Rovatirelin
Rovatirelin is under investigation in clinical trial NCT01384435 (A Phase II Double Blind Comparative Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)).
Investigational
Matched Description: … Rovatirelin is under investigation in clinical trial NCT01384435 (A Phase II Double Blind Comparative …
GSK2798745
GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough).
Investigational
Matched Description: … GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness …
LY3884961
LY3884961 (previously PR001) is being developed by Prevail Therapeutics as a single-dose gene therapy for patients with Parkinson's disease and Gaucher disease.
Investigational
Matched Description: … LY3884961 (previously PR001) is being developed by Prevail Therapeutics as a single-dose gene therapy …
MBP-091
MBP-091 is a monoclonal antibody being investigated for the treatment of Marburg virus disease (MVD) caused by infection with Marburg virus (MARV).
Investigational
Matched Description: … MBP-091 is a monoclonal antibody being investigated for the treatment of Marburg virus disease (MVD) …
MOR-22
MOR-22, a Natural human lymphoblastoid interferon-alpha, is currently being investigated to treat papillomavirus warts in the oral cavity of HIV-positive patients.
Investigational
Matched Description: … MOR-22, a Natural human lymphoblastoid interferon-alpha, is currently being investigated to treat papillomavirus …
Cellspan Esophageal Implant
The Cellspan Esophageal ImplantTM (CEI) composes of autologous adipose-derived mesenchymal stromal cells (Ad-MSC) seeded onto a polyurethane tubular mesh cell delivery device.
Investigational
Matched Description: … ImplantTM (CEI) composes of autologous adipose-derived mesenchymal stromal cells (Ad-MSC) seeded onto a …
Displaying drugs 11076 - 11100 of 11952 in total