Displaying drugs 576 - 600 of 1588 in total
Janssen COVID-19 Vaccine
The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. The vaccine was created in collaboration with Johnson and Johnson (J&J), Janssen Pharmaceutical, and the Beth Israel Deaconess Medical Center. A preclinical study in hamsters infected with...
Approved
Investigational
Matched Synonyms: … AD26.COV2.S [RECOMBINANT] …
Matched Description: … 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. ... The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype …
Matched Description: … 26 (Ad26) vector expressing a stabilized SARS-CoV-2 spike protein. ... The Janssen COVID-19 vaccine (Ad26.COV2.S) is a recombinant vaccine that contains an adenovirus serotype …
Elosulfase alfa
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Recombinant human N-acetylgalactosamine-6-sulfatase ... Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS) …
Matched Categories: … Recombinant Proteins …
Matched Categories: … Recombinant Proteins …
Salmon calcitonin
Synthetic peptide, 32 residues long formulated as a nasal spray.
Approved
Investigational
Matched Synonyms: … Calcitonin salmon recombinant ... Recombinant salmon calcitonin …
Darbepoetin alfa
Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Approved
Investigational
Matched Synonyms: … Darbepoetin alfa,recombinant …
Matched Description: … Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. …
Matched Description: … Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. …
Thrombin alfa
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Human Thrombin (recombinant, glycosylated) …
Matched Description: … Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. ... culture medium as single chain form that is proteolytically converted to a two-chain active form (using a protein …
Matched Description: … Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically ... The thrombin alfa product ultimate comes from recombinant human prethrombin-1 [L2079]. ... culture medium as single chain form that is proteolytically converted to a two-chain active form (using a protein …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Matched Description: … Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup c. The vaccine contains N. meningitis serogroup c capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Synonyms: … Neisseria meningitidis serogroup C capsular polysaccharide diphtheria toxoid protein conjugate vaccine …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Matched Description: … capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein …
Haemophilus influenzae b polysaccharide-tetanus conjugate
Approved
Matched Synonyms: … Haemophilus influenzae type b polysaccharide conjugated to tetanus protein ... Haemophilus influenzae type b polysaccharide conjugated to the tetanus protein …
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin detemir recombinant …
Matched Description: … [A2358, A2359, A2360, A44] Insulin also inhibits hepatic glucose production, enhances protein synthesis ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Matched Description: … [A2358, A2359, A2360, A44] Insulin also inhibits hepatic glucose production, enhances protein synthesis ... [A2358, A2359, A2360, A44] Insulin detemir is produced using recombinant DNA technology in yeast cells …
Galsulfase
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human …
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … Mecasermin recombinant ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 …
Matched Description: … Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label ... The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the …
Matched Categories: … Recombinant Human Insulin-like Growth Factor-1 …
Human albumin microspheres
Approved
Experimental
Matched Synonyms: … Protein-type A microspheres …
Matched Mixtures name: … Optison Perflutren Protein-Type A Microspheres …
Matched Mixtures name: … Optison Perflutren Protein-Type A Microspheres …
Erythropoietin
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Synonyms: … Epoetin alfa, recombinant ... Erythropoietin (recombinant human) ... Erythropoietin (human, recombinant) …
Matched Description: … Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant …
Matched Description: … Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant …
Nesiritide
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Approved
Investigational
Matched Synonyms: … Nesiritide recombinant …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Matched Description: … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. …
Insulin human
Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin. Typically prescribed for the management of diabetes mellitus,...
Approved
Investigational
Matched Synonyms: … Insulin recombinant human ... Insulin recombinant purified human …
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the …
Matched Description: … Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis ... Human insulin is produced by recombinant DNA technology and is identical to endogenously produced insulin ... Human Insulin is a 51 residue peptide hormone produced by recombinant DNA technology by inserting the …
Cerliponase alfa
Cerliponase alfa is an enzyme replacement treatment for a specific form of Batten disease. It was the first FDA-approved treatment to slow loss of walking ability (ambulation) in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl...
Approved
Investigational
Matched Synonyms: … Immature cell growth-inhibiting gene 1 protein …
Paclitaxel
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Synonyms: … paclitaxel protein-bound particles ... Paclitaxel protein-bound particles for injection suspension …
Matched Categories: … Narrow Therapeutic Index Drugs ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …
Matched Categories: … Narrow Therapeutic Index Drugs ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …
Teduglutide
Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine). The significance of this substitution is that teduglutide...
Approved
Matched Synonyms: … Teduglutide Recombinant …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Matched Description: … It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant …
Antihemophilic factor human
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Synonyms: … F8 protein, human …
Matched Description: … human plasma, rather than being produced through recombinant DNA technology. ... Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant ... similar structure and function to Antihemophilic factor human include [DB13999], which is produced by recombinant …
Matched Categories: … Protein Precursors …
Matched Description: … human plasma, rather than being produced through recombinant DNA technology. ... Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant ... similar structure and function to Antihemophilic factor human include [DB13999], which is produced by recombinant …
Matched Categories: … Protein Precursors …
Alglucosidase alfa
Aglucosidase alfa consists of the human enzyme acid alpha-glucosidase (GAA) which is essential for the degradation of glygogen to glucose in lysosomes. It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell...
Approved
Matched Synonyms: … Human acid precursor alpha-glucosidase, recombinant …
Matched Description: … Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Matched Description: … Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. …
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Categories: … Recombinant Proteins …
Matched Categories: … Recombinant Proteins …
Liraglutide
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … Liraglutide recombinant …
Matched Categories: … Protein Precursors …
Matched Categories: … Protein Precursors …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin …
Matched Categories: … Recombinant Proteins ... Recombinant Fusion Proteins …
Tositumomab
Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Approved
Investigational
Matched Categories: … Therapeutic Radiopharmaceuticals …
Matched Products: … Bexxar Therapeutic …
Matched Products: … Bexxar Therapeutic …
Capsicum
Capsicum (Chili pepper) allergenic extract is used in allergenic testing.
Approved
Matched Products: … Therapeutic Herbal Muscle Calm Capsicum …
Displaying drugs 576 - 600 of 1588 in total