Displaying drugs 3901 - 3925 of 5185 in total
CLZ-2002
CLZ-2002 consists of allogeneic mesenchymal stem cells derived neuronal regeneration-promoting cells.
Investigational
MBX-2109
MBX-2109 is a long-acting parathyroid hormone peptide prodrug under investigation for the treatment of hyperparathyroidism.
Investigational
CTCE-9908
Investigational
Matched Synonyms: … SDF-1 (108) Lysine Dlmer …
Matched Iupac: … ]acetamido}-3-methylbutanamido]-3-hydroxypropanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(4 ... (2S)-2,6-bis[(2S)-5-carbamimidamido-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2,6-diaminohexanamido …
Matched Iupac: … ]acetamido}-3-methylbutanamido]-3-hydroxypropanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(4 ... (2S)-2,6-bis[(2S)-5-carbamimidamido-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2,6-diaminohexanamido …
GTI-2501
GTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial. The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer. Initial testing has demonstrated strong antitumor...
Investigational
VB2-011
VB2-011 is an antibody developed as an anti-cancer treatment. According to some preclinical studies, it has a potential to inhibit tumour growth in various cancers including lymphoma and melanoma. This drug includes the parent IgM (H11 IgM) and a recombinant IgG version (H11 IgG).
Investigational
IPH 2101
IPH-2101 (NN-1975), a fully human monoclonal antibody developed for patients with acute myeloid leukemia.
Investigational
MBX-2982
MBX-2982 has been used in trials studying the treatment of Diabetes.
Investigational
Matched Iupac: … 5-ethyl-2-[4-(4-{[4-(1H-1,2,3,4-tetrazol-1-yl)phenoxy]methyl}-1,3-thiazol-2-yl)piperidin-1-yl]pyrimidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CMX-2043
CMX-2043 has been used in trials studying the treatment and prevention of Non STEMI, Unstable Angina, Stable Coronary Artery Disease, and Percutaneous Coronary Intervention.
Investigational
Matched Iupac: … (4S)-4-{[(1S)-1-carboxyethyl]carbamoyl}-4-{5-[(3R)-1,2-dithiolan-3-yl]pentanamido}butanoic acid …
SCB-2019
SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. This vaccine candidate resembles the native trimeric viral spike and is produced through mammalian cell-culture.
The vaccine was developed and tested by Clover Biopharmaceuticals AUS Pty Ltd.. As of June 2020, the company is pursuing a...
Investigational
KITE-222
Investigational
Matched Synonyms: … (CLL-1) ... express an antibody-derived single-chain variable fragment that recognizes C-type lectin-like molecule-1 …
DYNE-251
DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1). It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping.
Investigational
Matched Description: … morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 …
XMT-2056
XMT-2056 is a HER2-targeted antibody-drug conjugate (ADC) consisting of a HER2-targeted antibody conjugated with a stimulator of interferon genes (STING) agonist payload.
Investigational
ASP-2138
ASP-2138 is a bispecific antibody directed against CLDN18.2 and T cell receptor complex CD3
Investigational
Fepixnebart
Fepixnebart is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis).
Investigational
Matched Synonyms: … (HUMAN-MUS MUSCULUS MONOCLONAL LY3016859 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL …
Bunamiodyl
Withdrawn from the Canadian, US, and UK markets in 1963 due to nephropathy.
Withdrawn
Matched Synonyms: … 2-(3-Butyramido-3,4,6-triiodophenylmethylene)butyric acid …
Matched Iupac: … (2E)-2-[(3-butanamido-2,4,6-triiodophenyl)methylidene]butanoic acid …
Matched Iupac: … (2E)-2-[(3-butanamido-2,4,6-triiodophenyl)methylidene]butanoic acid …
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … SIGLEC-8, SAF-2))HUMANIZED MOUSE MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (VH (HOMO SAPIENS IGHV3 ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY MEMBER 2, ... G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL AK002 .GAMMA.1- …
Rifalazil
Rifalazil is a derivative of the antibiotic rifamycin. It is being investigated by ActivBiotics for the treatment of various bacterial infections.
Investigational
Matched Synonyms: … 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin …
Matched Iupac: … (2-methylpropyl)piperazin-1-yl]-6,23,37-trioxo-8,27,38-trioxa-24,34-diazahexacyclo[23.11.1.1^{4,7}.0^ ... ,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30-[4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Iupac: … (2-methylpropyl)piperazin-1-yl]-6,23,37-trioxo-8,27,38-trioxa-24,34-diazahexacyclo[23.11.1.1^{4,7}.0^ ... ,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-30-[4- …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Divozilimab
Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cd20 antigen) (human-mus musculus monoclonal bcd-132 .gamma.1-chain), …
Thymosin beta-4
Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, and Dry Eye Syndrome, among others.
Investigational
Matched Synonyms: … Thymosin beta 4 …
Matched Name: … Thymosin beta-4 …
Matched Description: … Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, …
Matched Name: … Thymosin beta-4 …
Matched Description: … Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, …
EDIT-301
EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Basic Fibroblast Growth Factor
Basic Fibroblast Growth Factor (bFGF) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of physiologic angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative...
Investigational
Matched Synonyms: … FGF 2 ... Heparin-binding growth factor 2 ... KCB-1 …
Matched Description: … protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... chemical properties and to distinguish it from acidic fibroblast growth factor (Fibroblast Growth Factor 1) …
Matched Categories: … Fibroblast Growth Factor 2, antagonists & inhibitors …
Matched Description: … protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 ... It has a 55 percent amino acid residue identity to Fibroblast Growth Factor 1 and has potent heparin-binding ... chemical properties and to distinguish it from acidic fibroblast growth factor (Fibroblast Growth Factor 1) …
Matched Categories: … Fibroblast Growth Factor 2, antagonists & inhibitors …
Timbetasin
Timbetasin is under investigation in clinical trial NCT05555589 (Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2).
Investigational
Matched Synonyms: … 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)thymosin .beta.4(human) ... Thymosin .beta.(4), 3,11,25,31,38-pentakis(de-n6-acetyl)-1,22,30,33-tetrakis(de-o3-phosphono)- …
Matched Description: … Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2) …
Matched Description: … Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2) …
SD118
SD118 was previously under investigation in Japan for a different indication and now, following re-profiling and evaluation in experimental animal models, has demonstrated its potential as a new oral therapy for neuropathic pain.
Investigational
Displaying drugs 3901 - 3925 of 5185 in total