Displaying drugs 5051 - 5075 of 5902 in total
ABT-510
ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and slows tumor growth. It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.
Investigational
Matched Iupac: … ]-3-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide ... -2-[(2S)-3-methyl-2-{2-[2-(N-methylacetamido)acetamido]acetamido}butanamido]pentanamido]butanamido]pentanamido ... (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S,3S)-2-[(2S)-2-[(2S,3R)-3-hydroxy-2-[(2R,3S)-3-methyl …
Golotimod
SCV-07 (g -D-glutamyl-L-tryptophan) is a novel synthetic dipeptide that acts broadly on the Toll-like receptor pathway. It has been shown to stimulate T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 and INF-g production. Due to this preferential activation of Th1 cytokine production, SCV-07 may show utility in...
Investigational
Matched Iupac: … (2R)-2-amino-4-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}butanoic acid …
Matched Description: … T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 …
Matched Description: … T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 …
Selepressin
Selepressin has been used in trials studying the treatment of Septic Shock.
Investigational
Matched Iupac: … pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(propan-2-yl)amino]pentanamide ... 10-(3-carbamoylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl] ... (2S)-2-{[(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-16-benzyl-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)- …
Guanosine
Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate) which are factors in signal transduction pathways.
Experimental
Investigational
Matched Synonyms: … 2(3H)-imino-9-β-D-ribofuranosyl-9H-purin-6(1H)-one ... 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one …
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Anti-SARS-CoV-2 equine immunoglobulin fragments
Anti-SARS-CoV-2 equine immunoglobulin fragments, also known as INOSARS, is a polyvalent passive immunization being tested in the clinical trial NCT04514302 (Safety and Efficacy of Anti-SARS-CoV-2 Equine Antibody Fragments (INOSARS) for Hospitalized Patients With COVID-19). INOSARS is composed of F(ab’)2 fragments extracted from hyperimmune equine serum.
Investigational
Matched Synonyms: … Anti-SARS-CoV-2 equine immunoglobulin fragments F(ab')2 …
Matched Name: … Anti-SARS-CoV-2 equine immunoglobulin fragments …
Matched Description: … [L27796] INOSARS is composed of F(ab’)2 fragments extracted from hyperimmune equine serum. ... Anti-SARS-CoV-2 equine immunoglobulin fragments, also known as INOSARS, is a polyvalent passive immunization ... being tested in the clinical trial NCT04514302 (Safety and Efficacy of Anti-SARS-CoV-2 Equine Antibody …
Matched Name: … Anti-SARS-CoV-2 equine immunoglobulin fragments …
Matched Description: … [L27796] INOSARS is composed of F(ab’)2 fragments extracted from hyperimmune equine serum. ... Anti-SARS-CoV-2 equine immunoglobulin fragments, also known as INOSARS, is a polyvalent passive immunization ... being tested in the clinical trial NCT04514302 (Safety and Efficacy of Anti-SARS-CoV-2 Equine Antibody …
Lucatumumab
Investigational
TALL-104
Investigational
CHF5633
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
HCV-086
HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.
Investigational
Matched Iupac: … 2-(4-fluorophenyl)-6-methanesulfonamido-N-methyl-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide …
Oclacitinib
Investigational
Vet approved
Matched Iupac: … N-methyl-1-{4-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]cyclohexyl}methanesulfonamide …
Piromelatine
Piromelatine has been used in trials studying the treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxo-4H-pyran-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Resminostat
Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others.
Investigational
Matched Iupac: … (2E)-3-(1-{4-[(dimethylamino)methyl]benzenesulfonyl}-1H-pyrrol-3-yl)-N-hydroxyprop-2-enamide …
Denibulin
Denibulin is a novel small molecule Vascular Disrupting Agent under development by MediciNova for treatment of solid tumor cancers.
Investigational
Matched Iupac: … methyl N-[5-({4-[(2S)-2-aminopropanamido]phenyl}sulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Darexaban
Darexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
Investigational
Matched Iupac: … N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4-(4-methyl-1,4-diazepan-1-yl)benzamide …
Matched Salts cas: … 365462-24-4 …
Matched Salts cas: … 365462-24-4 …
Edasalonexent
Edasalonexent is under investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 Diabetes).
Investigational
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-N-{2-[(2-hydroxyphenyl)formamido]ethyl}docosa-4,7,10,13,16,19-hexaenamide …
Matched Description: … investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 …
Matched Description: … investigation in clinical trial NCT01511900 (A Multiple Ascending Dose Study of CAT-1004 in Patients With Type 2 …
PF-05105679
PF-05105679 is under investigation in clinical trial NCT01393652 (Single Dose, Dose Escalation Healthy Volunteers Study Of PF-05105679).
Investigational
Matched Iupac: … 3-({N-[(1R)-1-(4-fluorophenyl)ethyl]-1-(quinolin-3-yl)formamido}methyl)benzoic acid …
Revaprazan
Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)).
Investigational
Matched Iupac: … N-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidin-2-amine …
Matched Description: … Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Menaquinone 6
Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
Investigational
Matched Iupac: … 2-[(2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl]-3-methyl-1,4- …
Matched Categories: … Vitamin K 2 …
Matched Categories: … Vitamin K 2 …
Cannabidivarin
Cannabidivarin, also known as cannabidivarol or CBDV, is a non-psychoactive cannabinoid found within DB14009. It is one of over 100 cannabinoids identified from the Cannabis plant that can modulate the physiological activity of cannabis, or marijuana . Compared to its homolog, DB09061, CBDV is shortened by two methyl (CH2) groups...
Investigational
Matched Synonyms: … 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol …
Matched Description: … arachidonoylglycerol (2-AG) [A33296, A33347]. ... many of their physiological effects through their binding to the cannabinoid-1 (CB1R) and cannabinoid-2 ... diacylglycerol (DAG) lipase-α, the primary enzyme responsible for the synthesis of the endocannabinoid, 2- …
Matched Iupac: … 2-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol …
Matched Description: … arachidonoylglycerol (2-AG) [A33296, A33347]. ... many of their physiological effects through their binding to the cannabinoid-1 (CB1R) and cannabinoid-2 ... diacylglycerol (DAG) lipase-α, the primary enzyme responsible for the synthesis of the endocannabinoid, 2- …
Furfural
Investigational
Matched Synonyms: … 2-Formylofuran ... 2-Furil-metanale ... 2-Furankarbaldehyd …
Matched Iupac: … furan-2-carbaldehyde …
Matched Iupac: … furan-2-carbaldehyde …
Canfosfamide
Canfosfamide is an active agent in chemotherapy-resistant ovarian cancer.
Investigational
Matched Iupac: … (2S)-2-amino-4-{[(1R)-2-[2-({bis[bis(2-chloroethyl)amino]phosphoryl}oxy)ethanesulfonyl]-1-{[(R)-carboxy …
L-Cycloserine
Investigational
Matched Synonyms: … (s)-4-amino-3-isoxazolidinone …
Matched Iupac: … (4S)-4-amino-1,2-oxazolidin-3-one …
Matched Iupac: … (4S)-4-amino-1,2-oxazolidin-3-one …
VAC-52150
Investigational
Neoantigen specific TCR-T cell therapy
Investigational
Apomorphine palmitate
Investigational
Matched Iupac: … (9R)-4-(hexadecanoyloxy)-10-methyl-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,13,15 …
Displaying drugs 5051 - 5075 of 5902 in total