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Displaying drugs 3701 - 3725 of 4205 in total
Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Synonyms: … 4-OH-A
Matched Iupac: … 9bS,11aS)-6-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … It is not US FDA approved, and the intramuscular injection form of formestane (Lentaron) which was approved ... and mild aromatase inhibitor activity. ... and less expensive than formestane, formestane lost popularity. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Drugs that are Mainly Renally Excreted …
Investigational
Matched Synonyms: … cells loaded with antigen from self-renewing, proliferating autologous irradiated tumour cells, in a
ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).
Investigational
Matched Synonyms: … autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) …
Matched Description: … ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a
Experimental
Matched Name: … Nicotinamide-adenine-dinucleotide-5-hydroxy-4-oxonorvaline …
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … NAGLU-IGF2 fusion protein ... Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein
Matched Description: … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human ... It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins ... Proteins ... Blood Proteins
A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid ... A narcotic used as a pain medication. ... Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States. …
Matched Salts name: … Nalbuphine hydrochloride
Matched Products: … Nalbuphine Hydrochloride
Ganaplacide is under investigation in clinical trial NCT03167242 (Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria).
Investigational
Matched Synonyms: … 2-Amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-5,6-dihydro-8,8-dimethylimidazo[1,2-a]pyrazin …
Matched Iupac: … 2-amino-1-[2-(4-fluorophenyl)-3-[(4-fluorophenyl)amino]-8,8-dimethyl-5H,6H,7H,8H-imidazo[1,2-a]pyrazin …
Matched Description: … With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum Malaria). ... Ganaplacide is under investigation in clinical trial NCT03167242 (Efficacy and Safety of KAF156 in Combination …
Experimental
Matched Name: … acid ... -3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic …
Matched Iupac: … -5-[(phosphonooxy)methyl]oxolan-2-yl]-1H-imidazol-5-yl}prop-2-enamido]phenyl}formamido)pentanedioic acid
Investigational
Matched Synonyms: … ALT-803 COMPONENT IL-15R.ALPHA.SU/FC FUSION PROTEIN ... CHAIN (HUMAN SUSHI DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT ... INTERLEUKIN 15 RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Recombinant Proteins
Experimental
Matched Name: … BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE …
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Approved
Investigational
Matched Description: … An antineoplastic agent. It has significant activity against melanomas. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Drugs that are Mainly Renally Excreted ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … AL QUIBAZINA® ... TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Approved
Matched Description: … It is active as an alkylating agent and an immunosuppressive agent. ... Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Drugs that are Mainly Renally Excreted ... Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index …
Matched Products: … IFOSFAMIDA 1G POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE. …
Investigational
Matched Synonyms: … EXOENZYME C3 TRANSFERASE (CLOSTRIDIUM BOTULINUM VARIANT VX-210) FUSION PROTEIN WITH TRANSPORT PEPTIDE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Proteins ... Bacterial Proteins
Investigational
Matched Synonyms: … Heat shock protein-peptide complex-96 vaccine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins
Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Synonyms: … di-(4-hydroxy-3-coumarinyl)methane …
Matched Description: … In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases ... Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. …
Matched Categories: … Blood and Blood Forming Organs ... Coumarins ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Experimental
Matched Name: … Uridine-5'-Diphosphate-N-Acetylmuramoyl-L-Alanine …
Matched Iupac: … (hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}propanamido]propanoic acid
Experimental
Matched Name: … N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Experimental
Matched Name: … D-leucyl-N-(3-chlorobenzyl)-L-prolinamide …
Experimental
Matched Name: … D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Experimental
Matched Name: … D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (UV, formaldehyde inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009 X-179A (H1N1) hemagglutinin antigen (formaldehyde inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/California/7/2009 X-181 (H1N1) hemagglutinin antigen (formaldehyde inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Christchurch/16/2010 NIB-74XP (H1N1) hemagglutinin antigen (formaldehyde inactivated …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen (MDCK cell derived, propiolactone inactivated …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
Displaying drugs 3701 - 3725 of 4205 in total