Displaying drugs 851 - 875 of 1351 in total
NB-124 sulfate
Investigational
Matched Synonyms: … -d-allofuranosyl-(1->5)-o-(2-amino-2,7-dideoxy-d-glycero-.alpha. ... D-streptamine, o-5-amino-5,6-dideoxy-.beta. ... -d-gluco-heptopyranosyl-(1->4))-2-deoxy-, sulfate …
Forodesine
Forodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic leukemia and cutaneous T-cell lymphoma. Additional preliminary findings support its use for the management of some B-cell malignancies.
Investigational
Matched Synonyms: … (1S)-1,4-dideoxy-4-imino-(9-deazahypoxanthin-9-yl)-D-ribitol ... 1,4-Dideoxy-4-aza-1-(S)-(9-deazahypoxanthin-9-yl)-D-ribitol …
Matched Iupac: … 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Description: … rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and ... clinical utility against T-cell acute lymphoblastic leukemia and cutaneous T-cell lymphoma. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Description: … rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and ... clinical utility against T-cell acute lymphoblastic leukemia and cutaneous T-cell lymphoma. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Chloramphenicol
An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Synonyms: … D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol ... D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamide …
Matched Description: … It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. ... It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. ... Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Ophthalmological and Otological Preparations …
Matched Products: … Chloroptic Dps 0.5% …
Matched Description: … It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. ... It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. ... Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Ophthalmological and Otological Preparations …
Matched Products: … Chloroptic Dps 0.5% …
Cassia fistula fruit
Experimental
Matched Synonyms: … Golden shower fruit ... Golden shower tree fruit ... Golden shower cassia fruit …
Immucillin-G
Experimental
Matched Synonyms: … (1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-D-ribitol …
Matched Iupac: … 2-amino-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin …
Matched Iupac: … 2-amino-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin …
2-Iminobiotin
Experimental
Investigational
Matched Synonyms: … Hexahydro-2-imino-1h-thieno(3,4-d)imidazole-4-pentanoic acid …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-amino-1H,3aH,4H,6H,6aH-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Categories: … Enzymes and Coenzymes …
Matched Iupac: … 5-[(3aS,4S,6aR)-2-amino-1H,3aH,4H,6H,6aH-thieno[3,4-d]imidazol-4-yl]pentanoic acid …
Matched Categories: … Enzymes and Coenzymes …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA. ... -D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. ... -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- …
Matched Description: … of breath and the coughing up of blood. ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. ... that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and …
Matched Categories: … cefepime and amikacin …
Matched Description: … of breath and the coughing up of blood. ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. ... that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and …
Matched Categories: … cefepime and amikacin …
Dideoxyadenosine
Investigational
Matched Synonyms: … -d-glycero-pentofuranosyl)purine ... -d-glycero-pentofuranosyl)-9h-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide
Experimental
Matched Synonyms: … D-Gluconamide, N,N'-((((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propanediyl ... N,N'-((((3alpha,5beta,12alpha)-3,12-Dihydroxy-24-oxocholan-24-yl)imino)di-3,1-propandiyl)bis-D-gluconamide ... N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide …
Matched Name: … N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide …
Matched Name: … N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide …
Amuvatinib
Amuvatinib has been used in trials studying the treatment of Solid Tumors and Small Cell Lung Carcinoma. Amuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA...
Investigational
Matched Synonyms: … 1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-d)pyrimidin-4-yl- ... 4-[1]Benzofuro[3,2-D]Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-Carbothioamide ... N-(1,3-Benzodioxol-5-ylmethyl)-4-(benzofuro(3,2-d)pyrimidin-4-yl)piperazine-1- carbothioamide …
Matched Description: … the mutant forms of c-KIT, PDGFR and FLT3. ... Amuvatinib has been used in trials studying the treatment of Solid Tumors and Small Cell Lung Carcinoma ... Amuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and …
Matched Description: … the mutant forms of c-KIT, PDGFR and FLT3. ... Amuvatinib has been used in trials studying the treatment of Solid Tumors and Small Cell Lung Carcinoma ... Amuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and …
Nerofe
Nerofe is under investigation in clinical trial NCT03059615 (A Phase 2a, Open-Label, Two Stage Study of Nerofe or Nerofe With Doxorubicin in Subjects With AML or MDS).
Investigational
Matched Synonyms: … WWTFFLPSTLWERK, (ALL D)- ... TRP-TRP-THR-PHE-PHE-LEU-PRO-SER-THR-LEU-TRP-GLU-ARG-LYS, (ALL D)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
2-deoxy-2-fluoro-α-D-glucose
Experimental
Matched Synonyms: … 2-deoxy-2-fluoro-alpha-D-glucose …
Matched Name: … 2-deoxy-2-fluoro-α-D-glucose …
Matched Name: … 2-deoxy-2-fluoro-α-D-glucose …
SP-876
Experimental
Matched Synonyms: … 1-[(4-{[(1S)-1,3-Dicarboxypropyl]carbamoyl}phenyl)sulfonyl]-D-prolyl-β-alanine …
DDP-225 free base anhydrous
Investigational
Matched Synonyms: … Thieno(2,3-d)pyrimidine, 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)- …
Matched Name: … DDP-225 free base anhydrous …
Matched Iupac: … 1-[4-(2-fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-2-yl]piperazine …
Matched Name: … DDP-225 free base anhydrous …
Matched Iupac: … 1-[4-(2-fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-2-yl]piperazine …
Piroxicam
A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … ARANTIL TOPIC ... VERAN-D ... Dom-piroxicam …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … ARANTIL TOPIC ... VERAN-D ... Dom-piroxicam …
Nitroglycerin
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Nitrates and Nitrites …
Matched Products: … TOP-NITRO ... Nitro-dur ... NITRO-DUR …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Nitrates and Nitrites …
Matched Products: … TOP-NITRO ... Nitro-dur ... NITRO-DUR …
Lysergic acid diethylamide
Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a manifestation of post-traumatic stress disorder, not related to the direct action of LSD...
Illicit
Investigational
Withdrawn
Matched Synonyms: … D-lysergic acid diethylamide ... N,N-diethyl-D-lysergamide …
Matched Description: … Debate continues over the nature and causes of chronic flashbacks. ... manifestation of post-traumatic stress disorder, not related to the direct action of LSD on brain chemistry, and …
Matched Categories: … Ergot Alkaloids and Derivatives …
Matched Description: … Debate continues over the nature and causes of chronic flashbacks. ... manifestation of post-traumatic stress disorder, not related to the direct action of LSD on brain chemistry, and …
Matched Categories: … Ergot Alkaloids and Derivatives …
alpha-Tocopherol succinate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … d-alpha-Tocopherol acid succinate ... Tocopheryl acid succinate,D-alpha …
Matched Description: … is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability ... esters using acetic or succinic acid, making a compound such as alpha-tocopherol succinate more stable and ... At the moment, however, there exists a lack of formal data and evidence to support any such additional …
Matched Mixtures name: … Formula Ma-vitamin E & Zinc Tab ... Vitamin E + 3 Extra Strength With Zinc ... Multi-Vitamin Fluoride and Iron Drops …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Webber Vitamin E Succ Cap 400unit(dri Caps) …
Matched Description: … is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability ... esters using acetic or succinic acid, making a compound such as alpha-tocopherol succinate more stable and ... At the moment, however, there exists a lack of formal data and evidence to support any such additional …
Matched Mixtures name: … Formula Ma-vitamin E & Zinc Tab ... Vitamin E + 3 Extra Strength With Zinc ... Multi-Vitamin Fluoride and Iron Drops …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Webber Vitamin E Succ Cap 400unit(dri Caps) …
Zanamivir
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... 5-(acetylamino)-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic acid …
3,4-Epoxybutyl-Alpha-D-Glucopyranoside
Experimental
Matched Name: … 3,4-Epoxybutyl-Alpha-D-Glucopyranoside …
Displaying drugs 851 - 875 of 1351 in total