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Displaying drugs 226 - 250 of 419 in total
Glibornuride
Glibornuride is a sulfonylurea-type anti-diabetic drug.
Investigational
Withdrawn
Matched Iupac: … 3-[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl]-1-(4-methylbenzenesulfonyl)urea …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Dihydrouracil
Experimental
Volixibat
Volixibat, also known as SHP626 or LUM002, is an investigational drug that will potentially be used for the treatment of Non-Alcoholic Steatohepatitis (NASH). If approved for use, it will be the first available agent for the treatment of NASH.
Volixibat is a selective inhibitor of the apical sodium-dependent bile acid...
Experimental
Investigational
Matched Iupac: … tetrahydro-1lambda6-benzothiepin-5-yl]phenyl}carbamoyl)amino]-3,5-dihydroxyoxan-2-yl]methoxy}sulfonic acid …
Matched Description: … Also known as the ileal bile acid transporter (IBAT), ASBT is primarily responsible for the enterohepatic ... Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane ... recirculation of bile acids and ultimately for hepatic lipid and glucose metabolism [A32120]. …
Matched Description: … Also known as the ileal bile acid transporter (IBAT), ASBT is primarily responsible for the enterohepatic ... Volixibat is a selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT), a transmembrane ... recirculation of bile acids and ultimately for hepatic lipid and glucose metabolism [A32120]. …
N-Acetyl-L-Citrulline
Experimental
Matched Iupac: … (2S)-5-(carbamoylamino)-2-acetamidopentanoic acid …
Carbazochrome
Carbazochrome is a hemostatic agent that promotes clotting, preventing blood loss from open wounds. It is an oxidation product of adrenaline which enhances the microcirculatory tone . In the future this may prevent excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on effectiveness and severity...
Experimental
Withdrawn
Matched Iupac: … {[(5Z)-3-hydroxy-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indol-5-ylidene]amino}urea …
Matched Description: … , but research on effectiveness and severity of side effects remains inconclusive. ... for use in the treatment of non-surgical acute uncomplicated hemorrhoids in a mixture with [DB13124], and ... this combination therapy demonstrated efficacy and safe tolerability either at a local or systemic level …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … , but research on effectiveness and severity of side effects remains inconclusive. ... for use in the treatment of non-surgical acute uncomplicated hemorrhoids in a mixture with [DB13124], and ... this combination therapy demonstrated efficacy and safe tolerability either at a local or systemic level …
Matched Categories: … Blood and Blood Forming Organs …
CAP-1
Experimental
Matched Iupac: … 1-(3-chloro-4-methylphenyl)-3-{2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}urea …
Imidapril
Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Investigational
Matched Iupac: … -{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid …
6-oxouridine 5'-phosphate
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2,4,6-trioxo-1,3-diazinan-1-yl)oxolan-2-yl]methoxy}phosphonic acid …
2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide
Experimental
Matched Iupac: … 1-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-3-[2-(4-fluorophenyl)acetyl]urea …
DCFBC
Experimental
Matched Iupac: … (2S)-2-({[(1R)-1-carboxy-2-{[(4-fluorophenyl)methyl]sulfanyl}ethyl]carbamoyl}amino)pentanedioic acid …
Gedatolisib
Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer, Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others.
Investigational
Matched Iupac: … -bis(morpholin-4-yl)-1,3,5-triazin-2-yl]phenyl}-3-{4-[4-(dimethylamino)piperidine-1-carbonyl]phenyl}urea …
Matched Description: … , Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others. ... Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer …
Matched Description: … , Breast Cancer, Advanced Cancer, and Endometrial Cancer, among others. ... Gedatolisib has been used in trials studying the basic science and treatment of Neoplasm, Ovary Cancer …
Tenidap
Experimental
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Iprazochrome
Experimental
Matched Iupac: … {[(5Z)-3-hydroxy-6-oxo-1-(propan-2-yl)-2,3,5,6-tetrahydro-1H-indol-5-ylidene]amino}urea …
N-Carbamoylphenylalanine
Experimental
Matched Iupac: … (2S)-2-(carbamoylamino)-3-phenylpropanoic acid …
K-134
K-134 has been used in trials studying the treatment of Intermittent Claudication.
Investigational
Matched Iupac: … 1-cyclopropyl-1-[(1R,2R)-2-hydroxycyclohexyl]-3-{3-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]propyl}urea …
Iofolastat I-123
Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).
Investigational
Matched Iupac: … (2S)-2-({[(1S)-1-carboxy-5-({[4-(¹²³I)iodophenyl]methyl}amino)pentyl]carbamoyl}amino)pentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
(S,R)-fidarestat
Experimental
Allantoate
Experimental
N-Carbamyl-D-Methionine
Experimental
Matched Iupac: … (2R)-2-(carbamoylamino)-4-(methylsulfanyl)butanoic acid …
Rebimastat
Investigational
Displaying drugs 226 - 250 of 419 in total