Displaying drugs 2476 - 2500 of 7247 in total
4,7-Dioxosebacic Acid
Experimental
3,3',5,5'-tetrachlorobiphenyl-4,4'-diol
Experimental
Oxolinic acid
Experimental
Matched Iupac: … 5-ethyl-8-oxo-2H,5H,8H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid …
Matched Categories: … 4-Quinolones …
Matched Categories: … 4-Quinolones …
CX157
CX157,3-fluoro-7-(2,2,2,-trifluoroethoxy)phenoxathiin-10,10-dioxide, is a reversible, selective inhibitor of MAO-A designed to have improved oral bioavailability and reduced clearance compared to previous MAO-A inhibitors of this class.
Investigational
Matched Description: … CX157,3-fluoro-7-(2,2,2,-trifluoroethoxy)phenoxathiin-10,10-dioxide, is a reversible, selective inhibitor …
Tenalisib
Tenalisib is under investigation in clinical trial NCT03711604 (Compassionate Use Study of Tenalisib (RP6530)).
Investigational
Matched Synonyms: … (S)-2-(1-(9H-Purin-6-Ylamino)Propyl)-3-(3-Fluorophenyl)-4H-Chromen-4-One) ... 3-(3-FLUOROPHENYL)-2-((1S)-1-((7H-PURIN-6-YL)AMINO)PROPYL)-4H-1-BENZOPYRAN-4-ONE ... 4H-1-BENZOPYRAN-4-ONE, 3-(3-FLUOROPHENYL)-2-((1S)-1-(9H-PURIN-6-YLAMINO)PROPYL)- …
Matched Iupac: … 3-(3-fluorophenyl)-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-4H-chromen-4-one …
Matched Iupac: … 3-(3-fluorophenyl)-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-4H-chromen-4-one …
2-methyl-5-methylidenepyrimidin-4-imine
Experimental
Matched Synonyms: … 4-Imino-5-Methidyl-2-Methylpyrimidine ... 2-Methyl-5-methylene-4(5H)-pyrimidinimine …
Matched Name: … 2-methyl-5-methylidenepyrimidin-4-imine …
Matched Iupac: … 2-methyl-5-methylidene-4,5-dihydropyrimidin-4-imine …
Matched Name: … 2-methyl-5-methylidenepyrimidin-4-imine …
Matched Iupac: … 2-methyl-5-methylidene-4,5-dihydropyrimidin-4-imine …
Aldumastat
Investigational
Matched Synonyms: … (5s)-5-cyclopropyl-5-(3-((3s)-4-(3,5-difluorophenyl)-3-methylpiperazin-1-yl)-3- oxopropyl)imidazolidine ... (s)-5-cyclopropyl-5-(3-((s)-4-(3,5-difluorophenyl)-3methylpiperazin-1-yl)-3-oxopropyl)imidazolidine-2,4 ... 2,4-imidazolidinedione, 5-cyclopropyl-5-(3-((3s)-4-(3,5-difluorophenyl)-3-methyl-1-piperazinyl)-3-oxopropyl …
TAS-106
TAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours .
Investigational
Matched Synonyms: … 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2 …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2 …
(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE
Experimental
Matched Name: … (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE …
Matched Iupac: … (4R,5R)-5-amino-1-[2-(2H-1,3-benzodioxol-5-yl)ethyl]-4-(2,4,5-trifluorophenyl)piperidin-2-one …
Matched Iupac: … (4R,5R)-5-amino-1-[2-(2H-1,3-benzodioxol-5-yl)ethyl]-4-(2,4,5-trifluorophenyl)piperidin-2-one …
Tomivosertib
Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine ... ]-1',5'-dione …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine ... ]-1',5'-dione …
AZD2066
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Receptor, Metabotropic Glutamate 5, antagonists & inhibitors …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Categories: … Receptor, Metabotropic Glutamate 5, antagonists & inhibitors …
Alferminogene tadenovec
Alferminogene tadenovec, Cardium’s lead product candidate, is being developed for the potential treatment of myocardial ischemia that gives rise to angina symptoms associated with coronary heart disease. Alferminogene tadenovec represents a new therapeutic class of biologics designed to promote angiogenesis and thereby improve blood flow following a one-time intracoronary administration...
Investigational
Matched Synonyms: … Ad5FGF-4 …
YK-4-279
Investigational
Matched Synonyms: … (S)-YK-4-279 ... 4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one …
Matched Name: … YK-4-279 …
Matched Name: … YK-4-279 …
4'-Thio-fac
4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With Advanced Solid Tumors and Lymphomas).
Investigational
Matched Synonyms: … 4-Amino-1-[(2R,3S,4S,5R)-3-Fluoro-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrothiophen-2-Yl] Pyrimidin-2(1H) …
Matched Name: … 4'-Thio-fac …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … 4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With …
Matched Name: … 4'-Thio-fac …
Matched Iupac: … 4-amino-1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … 4'-Thio-fac is under investigation in clinical trial NCT02661542 (Study of FF-10502-01 in Patients With …
Idrevloride
Investigational
Matched Synonyms: … 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl((2S,3R,4R, 5R)-2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl ... 3,5-diamino-6-chloro-n-(n-(4-(4-(2-(hexyl((2s,3r,4r,5r)-2,3,4,5,6-pentahydroxylhexyl)amino)ethoxy)phenyl ... D-glucitol, 1-deoxy-1-((2-(4-(4-(((((3,5-diamino-6-chloro-2-pyrazinyl)carbonyl)amino)iminomethyl)amino …
Matched Iupac: … 3,5-diamino-6-chloro-N-(N-{4-[4-(2-{hexyl[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]amino}ethoxy)phenyl …
Matched Iupac: … 3,5-diamino-6-chloro-N-(N-{4-[4-(2-{hexyl[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]amino}ethoxy)phenyl …
L-377202
L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).
Investigational
Matched Synonyms: … 5-((2s,4r)-2-(((1s)-2-(((1s)-2-(((1s)-2-(((1s)-4-amino-1-(((1s)-1-(hydroxymethyl)-2-(((1s)-1-(((2s,3s ... 5,12-NAPHTHACENEDIONE, 10-((3-(((4R)-1-(4-CARBOXY-1-OXOBUTYL)-4-HYDROXY-L-PROLYL-L-ALANYL-L-SERYL-(2S ... trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1h-tetracen-1-yl)oxy)tetrahydropyran-4- …
TAK-448
TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Investigational
Matched Iupac: … hydroxyphenyl)propanoyl]-4-hydroxypyrrolidin-2-yl]formamido}butanediamide ... (2S)-N-[(1S,2R)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-4- ... carbamoyl}amino)carbamoyl]-2-phenylethyl]carbamoyl}-2-hydroxypropyl]-2-{[(2S,4R)-1-[(2R)-2-acetamido-3-(4- …
KF-1601
Investigational
Matched Synonyms: … Benzamide, N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-[2-[ ... N-(3-(2-cyanopropan-2-yl)-5-(4-methyl-1H-imidazol-1-yl)phenyl)-2-fluoro-4-methyl-5-((8-((1-methyl-1H-pyrazol ... -4-yl)amino)imidazo[1,2-a]pyridin-3-yl)ethynyl)benzamide …
Matched Iupac: … N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl ... -1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl}ethynyl)benzamide …
Matched Iupac: … N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl ... -1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl}ethynyl)benzamide …
Saroglitazar
Saroglitazar has been investigated for the treatment of Fatty Liver.
Investigational
Matched Iupac: … (2S)-2-ethoxy-3-[4-(2-{2-methyl-5-[4-(methylsulfanyl)phenyl]-1H-pyrrol-1-yl}ethoxy)phenyl]propanoic acid …
Bimiralisib
Bimiralisib is under investigation in clinical trial NCT02723877 (PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)).
Investigational
Matched Synonyms: … 2-Pyridinamine, 5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)- ... 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine …
Matched Iupac: … 5-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)pyridin-2-amine …
Matched Iupac: … 5-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-4-(trifluoromethyl)pyridin-2-amine …
SB-269970
SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]
Investigational
Matched Iupac: … 3-{[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonyl}phenol …
Matched Description: … (5-HT7). ... suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 …
Matched Description: … (5-HT7). ... suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 …
Displaying drugs 2476 - 2500 of 7247 in total