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Displaying drugs 2501 - 2525 of 2962 in total
Experimental
Matched Synonyms: … beta-D-Glucose 6-phosphic acid
Matched Iupac: … {[(2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Synonyms: … (L)-2-Amino-3-(carboxymethylthio)propionic acid
Matched Iupac: … (2R)-2-amino-3-[(carboxymethyl)sulfanyl]propanoic acid
Matched Description: … Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD)[A231169] and other ... by physicians in France and Italy. ... viruses and bacteria in thick bronchial mucus. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... and mantle cell lymphoma. ... ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids ... Boronic Acids ... Acids, Noncarboxylic …
INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).
Investigational
Matched Synonyms: … 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN …
Experimental
Matched Synonyms: … 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid
Matched Iupac: … ,3S,5R)-5-(6,8-dihydroxy-2-imino-3,9-dihydro-2H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Technetium Tc 99m diisopropyl-iminodiacetic acid
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid technetium …
Matched Description: … uptake and fast biliary excretion, resulting in improved hepatic imaging. ... More specifically, mebrofenin is taken up into hepatocytes through the action of OATP1B1 and OATP1B3 ... Liver and gallbladder imaging is enabled through attachment to mebrofenin as this molecule has high hepatic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Indicators and Reagents ... Hepatic and Reticulo Endothelial System ... Amino Acids
Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)).
Investigational
Matched Synonyms: … Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-(3-CARBOXYPROPYL)-.OMEGA. …
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And
Matched Categories: … Enzymes and Coenzymes …
Investigational
Matched Synonyms: … L-leucine, l-tryptophyl-l-alanyl-l-prolyl-l-valyl-l-leucyl-l-.alpha. …
Experimental
Matched Name: … 5-(Hydroxy-Methyl-Amino)-3-Methyl-Pyrrolidine-2-Carboxylic Acid
Matched Iupac: … (2R,3R,5R)-5-[hydroxy(methyl)amino]-3-methylpyrrolidine-2-carboxylic acid
Experimental
Matched Name: … 2-Benzo[1,3]Dioxol-5-Ylmethyl-3-Benzyl-Succinic Acid
Matched Iupac: … (2S,3S)-2-[(2H-1,3-benzodioxol-5-yl)methyl]-3-benzylbutanedioic acid
Experimental
Matched Name: … 2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
Matched Iupac: … (3R)-2-{[1,1'-biphenyl]-4-sulfonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Experimental
Matched Name: … L-2-amino-4-methoxy-cis-but-3-enoic acid
Matched Iupac: … (2S,3Z)-2-amino-4-methoxybut-3-enoic acid
Experimental
Matched Name: … 3-[Isopropyl(4-Methylbenzoyl)Amino]-5-Phenylthiophene-2-Carboxylic Acid
Matched Iupac: … 5-phenyl-3-[N-(propan-2-yl)4-methylbenzamido]thiophene-2-carboxylic acid
Experimental
Matched Name: … 3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid
Matched Iupac: … 3-{[(E)-{[2-(trifluoromethyl)phenyl]methylidene}amino]oxy}propanoic acid
Experimental
Matched Name: … (3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acid
Matched Iupac: … (2R,3S)-2-ethyl-3-(4-methylbenzenesulfonamido)butanedioic acid
Experimental
Matched Name: … (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID
Matched Iupac: … 2-(5-chloro-2-{[(3-nitrophenyl)methyl]carbamoyl}phenoxy)acetic acid
Experimental
Matched Name: … 2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID
Matched Iupac: … 2',4'-dichloro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Experimental
Matched Name: … (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
Matched Iupac: … (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
Experimental
Matched Name: … (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
Matched Iupac: … (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
Experimental
Matched Name: … 5-Amino-6-cyclohexyl-4-hydroxy-2-isobutyl-hexanoic acid
Matched Iupac: … (2R,4S,5S)-5-amino-6-cyclohexyl-4-hydroxy-2-(2-methylpropyl)hexanoic acid
Experimental
Matched Name: … (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID
Matched Iupac: … 2-[2-(carbamoylmethyl)-5-propyl-1H-indol-7-yl]acetic acid
Experimental
Matched Name: … N-{[6-(PENTYLOXY)NAPHTHALEN-2-YL]SULFONYL}-D-GLUTAMIC ACID
Matched Iupac: … (2R)-2-[6-(pentyloxy)naphthalene-2-sulfonamido]pentanedioic acid
Experimental
Matched Name: … [4-R-(4-ALPHA,6-BETA,7-BETA]-HEXAHYDRO-5,6-DI(HYDROXY)-1,3-DI(ALLYL)-4,7-BISPHENYLMETHYL)-2H-1,3-DIAZEPINONE …
Investigational
Matched Synonyms: … human) fusion protein with peptide linker (gsgggs) fusion protein with 1-165-interleukin 2 receptor .alpha ... comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain of IL-2 receptor alpha
Displaying drugs 2501 - 2525 of 2962 in total