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Displaying drugs 2726 - 2750 of 2933 in total
Experimental
Matched Name: … 4-(3-ethylthiophen-2-yl)benzene-1,2-diol …
Matched Iupac: … 4-(3-ethylthiophen-2-yl)benzene-1,2-diol …
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Synonyms: … cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methylindole-5-carbamate
Matched Iupac: … cyclopentyl N-[3-({2-methoxy-4-[(2-methylbenzenesulfonyl)carbamoyl]phenyl}methyl)-1-methyl-1H-indol-5-yl]carbamate
Matched Description: … It is available as a tablet and is usually dosed twice daily. ... antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and ... and inflammation of the breathing passages. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Acids, Acyclic ... Carboxylic Acids
Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Synonyms: … (2-hydroxypropyl)trimethylammonium carbamate
Matched Iupac: … 1-(trimethylazaniumyl)propan-2-yl carbamate
Matched Description: … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function ... to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … (1s,3r)-3-(acetylamino)-n-(5-chloro-4-(5,6-dihydro-5,5-dimethyl-4h-pyrrolo(1,2-b)pyrazol-3-yl)-2-pyridinyl …
Gandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Investigational
Matched Synonyms: … 3-(4-CHLORO-2-FLUOROBENZYL)-2-METHYL-N-(5-METHYL-1H-PYRAZOL-3-YL)-8- (MORPHOLINOMETHYL)IMIDAZO(1,2-B) ... IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, 3-((4-CHLORO-2-FLUOROPHENYL)METHYL)-2-METHYL-N-(5- METHYL-1H-PYRAZOL …
Matched Iupac: … N-{3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-8-[(morpholin-4-yl)methyl]imidazo[1,2-b]pyridazin-6-yl …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and
Investigational
Matched Synonyms: … 6-{[(1r,2s)-2-Aminocyclohexyl]amino}-7-Fluoro-4-(1-Methyl-1h-Pyrazol-4-Yl)-1,2-Dihydro-3h-Pyrrolo[3,4 …
Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Matched Name: … Col-Treg …
Matched Description: … Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type …
Experimental
Matched Name: … 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione …
Matched Iupac: … 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)-4,7-dihydro-1H-indole-4,7-dione …
Investigational
Matched Synonyms: … N-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro ... PYRIDINECARBOXAMIDE, N-(3-FLUORO-4-((1-METHYL-6-(1H-PYRAZOL-4-YL)-1H-INDAZOL-5-YL)OXY)PHENYL)-1-(4-FLUOROPHENYL)-1,2
Matched Iupac: … -methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-2-oxo-6-(propan-2-yloxy)-1,2
Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy . In 2005,...
Approved
Experimental
Matched Synonyms: … 1,2-Dibromo-2,4-dicyanobutane …
Matched Description: … Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and ... It is also a known allergen and dermatological irritant that has been banned in many EU countries due …
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Bupivacaine Hydrochloride and Epinephrine ... Bupivacaine Hci and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … BUPIVACAINE HCL MONOHYDRATE
Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … 6-(1-methyl-1h-pyrazol-4-yl)-1-((6-(1-methyl-1h-pyrazol-4-yl)imidazo(1,2-a)pyridin-3-yl)sulfonyl)-1h-pyrazolo …
Matched Iupac: … 1-methyl-4-(3-{[6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[4,3-b]pyridin-1-yl]sulfonyl}imidazo[1,2-a]pyridin …
Matched Description: … Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety ... of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer). …
Investigational
Matched Synonyms: … 1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione, 4-ethyl-4-hydroxy-12-(2-hydroxyethoxy …
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances …
Experimental
Matched Name: … 2-(Pyrido[1,2-E]Purin-4-Yl)Amino-Ethanol …
Experimental
Matched Name: … S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea …
Experimental
Matched Synonyms: … (3S,8aS)-3-(1H-Imidazol-4-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Iupac: … (3S,8aS)-3-[(1H-imidazol-5-yl)methyl]-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … Sheep-rot leaf …
Experimental
Matched Synonyms: … Iodopropynyl butyl carbamate
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Experimental
Matched Name: … S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea …
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
Approved
Vet approved
Matched Description: … relaxants such as gallamine and tubocurarine. ... A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … NEOSTIGMINE INJECTION 2.5 MG/ML "CHI SHENG" …
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Synonyms: … (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane …
Matched Description: … [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the ... prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. …
Experimental
Matched Name: … N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine …
Matched Iupac: … (2S)-2-[(2S)-3-{[(1R)-1-aminoethyl](hydroxy)phosphoryl}-2-benzylpropanamido]-3-phenylpropanoic acid
Experimental
Matched Name: … N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE …
Matched Iupac: … (2S)-1-[(8aR)-octahydropyrrolo[1,2-a]pyrimidin-1-yl]-4-methylpentan-2-amine …
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … pyrrolidine-2,5-diyl]bis{(4,1-phenylene)carbamoyl(2S)pyrrolidine-2,1-diyl[(2S)-3-methyl-1-oxobutane-1,2
Matched Iupac: … pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
Matched Description: … categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... FDA- and Health Canada-approved product Technivie. ... Ombitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ombitasvir, paritaprevir and ritonavir ... dasabuvir, ombitasvir, paritaprevir and ritonavir ... Amino Acids ... Amino Acids, Cyclic …
Displaying drugs 2726 - 2750 of 2933 in total