Displaying drugs 3151 - 3175 of 3890 in total
CB-5083
Investigational
Matched Synonyms: … 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide ... 1-(7,8-Dihydro-4-((phenylmethyl)amino)-5H-pyrano(4,3-d)pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide …
Matched Iupac: … 1-[4-(benzylamino)-5H,7H,8H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide …
Matched Iupac: … 1-[4-(benzylamino)-5H,7H,8H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide …
N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine
Experimental
Matched Name: … N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine …
Matched Iupac: … (2S)-2-{[(1S)-1-{[(1S)-1-carbamoyl-2-carboxyethyl]carbamoyl}-2-phenylethyl]amino}-4-phenylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-{[(1S)-1-{[(1S)-1-carbamoyl-2-carboxyethyl]carbamoyl}-2-phenylethyl]amino}-4-phenylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine
Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …
Matched Iupac: … )-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy]phosphinic acid …
Matched Iupac: … )-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy]phosphinic acid …
Gemcitabine elaidate
Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Investigational
Matched Synonyms: … -D-2'DEOXY-2',2'-DIFLUOROCYTIDINE ... 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidine …
Matched Description: … been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Oxypurinol
Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Investigational
Matched Synonyms: … 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione …
Matched Iupac: … 1H,2H,4H,5H,6H-pyrazolo[3,4-d]pyrimidine-4,6-dione …
Matched Iupac: … 1H,2H,4H,5H,6H-pyrazolo[3,4-d]pyrimidine-4,6-dione …
Selpercatinib
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … 6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ulodesine
Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.
Investigational
Matched Synonyms: … 4H-PYRROLO(3,2-D)PYRIMIDIN-4-ONE, 1,5-DIHYDRO-7-(((3R,4R)-3-HYDROXY-4-(HYDROXYMETHYL)-1-PYRROLIDINYL) ... 7-(((3R,4R)-3-HYDROXY-4-(HYDROXYMETHYL)PYRROLIDIN-1-YL)METHYL(-1,5-DIHYDRO-4H-PYRROLO(3,2-D)PYRIMIDIN ... 7-(((3R,4R)-3-HYDROXY-4-(HYDROXYMETHYL)PYRROLIDIN-1-YL)METHYL)-3,5-DIHYDRO-4H-PYRROLO(3,2-D)PYRIMIDIN …
Matched Iupac: … 7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Description: … Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint …
Matched Salts name: … Ulodesine Hydrochloride …
Matched Iupac: … 7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Description: … Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint …
Matched Salts name: … Ulodesine Hydrochloride …
1-(5-phospho-D-ribosyl)-ATP
Experimental
Matched Name: … 1-(5-phospho-D-ribosyl)-ATP …
Matched Iupac: … 1H-purin-9-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 1H-purin-9-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Cytidine-5'-diphospho-beta-D-xylose
Experimental
Matched Name: … Cytidine-5'-diphospho-beta-D-xylose …
Matched Iupac: … dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
Matched Iupac: … dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid …
5-Thio-a/B-D-Mannopyranosylamine
Experimental
Matched Name: … 5-Thio-a/B-D-Mannopyranosylamine …
Matched Iupac: … (2S,3S,4S,5S,6R)-2-amino-6-(hydroxymethyl)thiane-3,4,5-triol …
Matched Iupac: … (2S,3S,4S,5S,6R)-2-amino-6-(hydroxymethyl)thiane-3,4,5-triol …
1,6-DI-O-PHOSPHONO-D-MANNITOL
Experimental
Matched Name: … 1,6-DI-O-PHOSPHONO-D-MANNITOL …
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-(phosphonooxy)hexyl]oxy}phosphonic acid …
D-phenylalanyl-N-benzyl-L-prolinamide
Experimental
Matched Name: … D-phenylalanyl-N-benzyl-L-prolinamide …
N-(biphenyl-4-ylsulfonyl)-D-leucine
Experimental
Matched Name: … N-(biphenyl-4-ylsulfonyl)-D-leucine …
Matched Iupac: … (2R)-2-{[1,1'-biphenyl]-4-sulfonamido}-4-methylpentanoic acid …
Matched Iupac: … (2R)-2-{[1,1'-biphenyl]-4-sulfonamido}-4-methylpentanoic acid …
AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH
Experimental
Matched Name: … AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH …
Matched Iupac: … (1R)-4-amino-1-{[(2S)-1-[(2R)-2-acetamido-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}butyl]boronic acid …
Matched Iupac: … (1R)-4-amino-1-{[(2S)-1-[(2R)-2-acetamido-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}butyl]boronic acid …
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone ... L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-Nim-benzyl-histidyl-L-leucyl-L-arginyl-L-proline ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid …
Matched Description: … to their capacity to reduce LH levels and the concentration of sex steroids. ... GnRH agonists are the first line of treatment for children with central precocious puberty (CPP) due …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid …
Matched Description: … to their capacity to reduce LH levels and the concentration of sex steroids. ... GnRH agonists are the first line of treatment for children with central precocious puberty (CPP) due …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
5-beta-D-ribofuranosylnicotinamide adenine dinucleotide
Experimental
Matched Name: … 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide …
N-[Tosyl-D-Prolinyl]Amino-Ethanethiol
Experimental
Matched Name: … N-[Tosyl-D-Prolinyl]Amino-Ethanethiol …
AC-(D)Phe-pro-borolys-OH
Experimental
Matched Name: … AC-(D)Phe-pro-borolys-OH …
Matched Iupac: … 1R)-5-amino-1-{[(2S)-1-[(2R)-2-acetamido-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}pentyl]boronic acid …
Matched Iupac: … 1R)-5-amino-1-{[(2S)-1-[(2R)-2-acetamido-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}pentyl]boronic acid …
N-[(4-methoxyphenyl)sulfonyl]-D-alanine
Experimental
Matched Name: … N-[(4-methoxyphenyl)sulfonyl]-D-alanine …
Matched Iupac: … (2R)-2-(4-methoxybenzenesulfonamido)propanoic acid …
Matched Iupac: … (2R)-2-(4-methoxybenzenesulfonamido)propanoic acid …
Quinestrol
The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Synonyms: … 17-alpha-Ethinylestradiol 3-cyclopentyl ether …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Quisovalimab
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside
Experimental
Matched Synonyms: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside ... diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-β-D-ribofuranosyl …
Matched Name: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... {[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl …
Matched Name: … ]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside ... {[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(piperidin-3-ylmethyl)amino]ethyl}-beta-D-ribofuranosyl …
Dasabuvir
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6 [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 …
Matched Description: … categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852]. ... Dasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational …
Matched Salts name: … Dasabuvir sodium monohydrate ... Dasabuvir sodium …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir …
Matched Description: … categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852]. ... Dasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational …
Matched Salts name: … Dasabuvir sodium monohydrate ... Dasabuvir sodium …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir …
AVR-48
Investigational
Matched Synonyms: … 4-nitrophenyl-n-acetyl-beta-d-glucosaminide ... -d-glucopyranoside, 4-nitrophenyl 2-(acetylamino)-2-deoxy- ... 4-nitrophenyl 2-acetamido-2-deoxy-beta-d-glucopyranoside …
Displaying drugs 3151 - 3175 of 3890 in total