Displaying drugs 3251 - 3275 of 9612 in total
TAK-603
Investigational
Matched Synonyms: … Ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate ... 3-quinolinecarboxylic acid, 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1h-1,2,4-triazol-1-ylmethyl)-, ethyl …
Matched Iupac: … ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-[(1H-1,2,4-triazol-1-yl)methyl]quinoline-3-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-[(1H-1,2,4-triazol-1-yl)methyl]quinoline-3-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Inbakicept
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … INTERLEUKIN 15 RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
PHA-767491
PHA-767491 is a Cdc7/CDK9 inhibitor.
Investigational
Matched Salts cas: … 845538-12-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Briquilimab
Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .GAMMA.1- …
Mosedipimod
Mosedipimod has been used in trials studying the supportive care and treatment of Chemotherapy-induced Neutropenia.
Investigational
Matched Synonyms: … 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol …
Matched Iupac: … 1-(acetyloxy)-3-(hexadecanoyloxy)propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Iupac: … 1-(acetyloxy)-3-(hexadecanoyloxy)propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Thymoquinone
Thymoquinone is a natural compound with widespread protective effects, including anti-oxidative, anti-inflammatory, immunomodulatory, anti-cancer, and anti-microbial.
Investigational
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Gimatecan
Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline ... (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline ... 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy …
Matched Iupac: … ]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione ... (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …
Matched Description: … Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative …
Matched Iupac: … ]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione ... (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …
Matched Description: … Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative …
Nemtabrutinib
Nemtabrutinib is under investigation in clinical trial NCT05624554 (A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)).
Investigational
Matched Synonyms: … (2-chloro-4-phenoxyphenyl)(4-(((3r,6s)-6-(hydroxymethyl)tetrahydro-2h-pyran-3-yl)amino)-7h-pyrrolo(2,3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
FN-1501
Investigational
Matched Synonyms: … 3-carboxamide ... 4-((7h-pyrrolo (2,3-d)pyrimidin-4-yl)amino)-n-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1h-pyrazole- …
Matched Iupac: … N-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}-4-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-1H-pyrazole-3 …
Matched Iupac: … N-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}-4-({7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-1H-pyrazole-3 …
Udifitimod
Udifitimod is under investigation in clinical trial NCT05014438 (A Study of BMS-986166 or Branebrutinib for the Treatment of Participants With Atopic Dermatitis).
Investigational
Matched Synonyms: … ((1R,3S)-1-amino-3-((S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol ... [(1R,3S)-1-amino-3-{(6S)-6-[2-(2-methoxyphenyl)ethyl]- 5,6,7,8-tetrahydronaphthalen-2-yl}cyclopentyl] ... Cyclopentanemethanol, 1-amino-3-((6s)-5,6,7,8-tetrahydro-6-(2-(2-methoxyphenyl)ethyl)-2-naphthalenyl) …
Opebacan
Investigational
Matched Synonyms: … 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN) ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN REDUCED) …
6-amino-1-methyl-7H-purin-1-ium
Experimental
Matched Synonyms: … 6-amino-1-methylpurine …
Matched Name: … 6-amino-1-methyl-7H-purin-1-ium …
Matched Iupac: … 6-amino-1-methyl-7H-purin-1-ium …
Matched Name: … 6-amino-1-methyl-7H-purin-1-ium …
Matched Iupac: … 6-amino-1-methyl-7H-purin-1-ium …
Elimusertib
Elimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors).
Investigational
Matched Synonyms: … 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)- …
Peruvoside
Experimental
Matched Iupac: … ,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-11-hydroxy-15-methyl-14-(5-oxo-2,5-dihydrofuran-3- …
BNT162c2 SARS-CoV-2 Vaccine
BNT162c2 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162c2 is a self-amplifying mRNA (saRNA) vaccine formulated in lipid nanoparticles for delivery via intramuscular injection.[L15002, L15007]
BNT162c2 is undergoing evaluation in clinical trials in both the USA (NCT04368728)...
Investigational
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Goflikicept
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 …
Matched Description: … Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Description: … Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Subasumstat
Subasumstat is under investigation in clinical trial NCT03648372 (A Study to Evaluate the Safety, Tolerability, Preliminary Efficacy and Pharmacokinetics (PK) of TAK-981 in Adult Participants With Advanced or Metastatic Solid Tumors or Relapsed/refractory Hematologic Malignancies and in a Subset With Coronavirus Disease 2019 (COVID-19)).
Investigational
Matched Iupac: … [(1R,2S,4R)-4-[(5-{4-[(1R)-7-chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl} …
Matched Description: … or Relapsed/refractory Hematologic Malignancies and in a Subset With Coronavirus Disease 2019 (COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Description: … or Relapsed/refractory Hematologic Malignancies and in a Subset With Coronavirus Disease 2019 (COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Sarconeos
Sarconeos is an activator of the MAS receptor.
Investigational
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Empasiprubart
Empasiprubart is a humanized sweeping antibody designed to bind to C2, a protein in the complement cascade that leads to cell destruction when activated.
Investigational
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
PLN-74809
PLN-74809 is a small-molecule that dually inhibits both αvβ6 and αvβ1 to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC) . The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in...
Investigational
Matched Description: … 74809 is a small-molecule that dually inhibits both αvβ6 and αvβ1< ... addition, the compound is also currently in Phase 2a trials (NCT04565249) for the treatment of COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 …
HE3286
Investigational
Matched Iupac: … (1R,3aS,3bR,4R,7S,9aR,9bS,11aS)-1-ethynyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H …
Exarafenib
Investigational
Matched Iupac: … (3S)-N-[3-(2-{[(2R)-1-hydroxypropan-2-yl]amino}-6-(morpholin-4-yl)pyridin-4-yl)-4-methylphenyl]-3-(2,2,2 ... -trifluoroethyl)pyrrolidine-1-carboxamide …
Irosustat
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Synonyms: … 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate …
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate …
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate …
1,2-Docosahexanoyl-sn-glycero-3-phosphoserine
Experimental
Matched Name: … 1,2-Docosahexanoyl-sn-glycero-3-phosphoserine …
Matched Iupac: … (2S)-2-amino-3-({[(2R)-3-[(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]-2-[(4Z,7Z,10Z,16Z, …
Matched Salts name: … 1,2-docosahexanoyl-sn-glycero-3-phosphoserine calcium …
Matched Iupac: … (2S)-2-amino-3-({[(2R)-3-[(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16,19-hexaenoyloxy]-2-[(4Z,7Z,10Z,16Z, …
Matched Salts name: … 1,2-docosahexanoyl-sn-glycero-3-phosphoserine calcium …
Displaying drugs 3251 - 3275 of 9612 in total