Displaying drugs 3301 - 3325 of 4067 in total
(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione
Experimental
Matched Name: … (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione …
Matched Iupac: … (3S)-3-hydroxy-1-methyl-2,3,5,6-tetrahydro-1H-indole-5,6-dione …
Matched Iupac: … (3S)-3-hydroxy-1-methyl-2,3,5,6-tetrahydro-1H-indole-5,6-dione …
5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine
Experimental
Matched Name: … 5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine …
Matched Iupac: … 5-({1-[(2,3-dichlorophenyl)methyl]piperidin-4-yl}methoxy)quinazoline-2,4-diamine …
Matched Iupac: … 5-({1-[(2,3-dichlorophenyl)methyl]piperidin-4-yl}methoxy)quinazoline-2,4-diamine …
N-[1-(5-bromo-2,3-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide
Experimental
Matched Name: … N-[1-(5-bromo-2,3-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide …
Matched Iupac: … N-{1-[(5-bromo-2,3-dimethoxyphenyl)methyl]piperidin-4-yl}-4-sulfanylbutanamide …
Matched Iupac: … N-{1-[(5-bromo-2,3-dimethoxyphenyl)methyl]piperidin-4-yl}-4-sulfanylbutanamide …
1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID
Experimental
Matched Name: … 1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID …
Matched Iupac: … 1-(3,5-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylic acid …
Matched Iupac: … 1-(3,5-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylic acid …
(RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE
Experimental
Matched Name: … (RP,SP)-O-(2R)-(1-PHENOXYBUT-2-YL)-METHYLPHOSPHONIC ACID CHLORIDE …
Matched Iupac: … (R)-((2R)-1-phenoxybutan-2-yl methylphosphonochloridate) …
Matched Iupac: … (R)-((2R)-1-phenoxybutan-2-yl methylphosphonochloridate) …
1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA
Experimental
Matched Name: … 1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA …
Matched Iupac: … 1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea …
4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE
Experimental
Matched Name: … 4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE …
3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL
Experimental
Matched Name: … 3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL …
Matched Iupac: … 3-{3-[(dimethylamino)methyl]-1H-indol-7-yl}propan-1-ol …
Matched Iupac: … 3-{3-[(dimethylamino)methyl]-1H-indol-7-yl}propan-1-ol …
1-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-2-(METHYLAMINO)ETHANONE
Experimental
Matched Name: … 1-(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)-2-(METHYLAMINO)ETHANONE …
Matched Iupac: … 1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-2-(methylamino)ethan-1-one …
Matched Iupac: … 1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-2-(methylamino)ethan-1-one …
1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
Experimental
Matched Name: … 1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl …
Matched Iupac: … 3-{5-[2-({1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)ethyl]-1,3-thiazol-2-yl}-1-[3-(trifluoromethyl …
Matched Iupac: … 3-{5-[2-({1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)ethyl]-1,3-thiazol-2-yl}-1-[3-(trifluoromethyl …
Mupirocin
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Description: … [A178531,A178591] Mupirocin is commonly marketed under the brand name Bactroban. ... and traumatic skin lesions due to secondary skin infections caused by _S. aureus_ and _S. pyogenes_. ... termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique chemical structure and …
Matched Mixtures name: … Pre and Post Sx Pouch ... Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... MUPOBEL %2 KREM , 15 GRAM ... BACODERM %2 15 GR KREM …
Matched Mixtures name: … Pre and Post Sx Pouch ... Metronidazole 1% / Mupirocin 2% / ... Metronidazole 1% / Mupirocin 2% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … MUPIGEN %2 POMAD , 15 G'LIK 1 TÜP ... MUPOBEL %2 KREM , 15 GRAM ... BACODERM %2 15 GR KREM …
Cysteamine
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … 2-amino-1-ethanethiol …
Matched Iupac: … 2-aminoethane-1-thiol …
Matched Description: … in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and ... preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and ... L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and …
Matched Salts cas: … 156-57-0 ... 27761-19-9 …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives …
Matched Products: … CYSTAGON ® 150 MG …
Matched Iupac: … 2-aminoethane-1-thiol …
Matched Description: … in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and ... preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and ... L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and …
Matched Salts cas: … 156-57-0 ... 27761-19-9 …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives …
Matched Products: … CYSTAGON ® 150 MG …
Apremilast
Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Matched Synonyms: … N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4- …
Matched Iupac: … N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl …
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and …
Matched Mixtures name: … OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Matched Products: … OTEZLA FILM-COATED TABLETS 10 MG …
Matched Iupac: … N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl …
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and …
Matched Mixtures name: … OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) ... OTEZLA (10 MG 20 MG 30 MG) …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Matched Products: … OTEZLA FILM-COATED TABLETS 10 MG …
Alectinib
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting ... Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ALECENSA (150 MG HARD CAPSULE) ... ALECENSA 150 MG SERT KAPSÜL, 224 ADET …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting ... Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ALECENSA (150 MG HARD CAPSULE) ... ALECENSA 150 MG SERT KAPSÜL, 224 ADET …
Enasidenib
Enasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with specific mutations in the isocitrate dehydrogenase 2 (IDH2) gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345]. Patients eligible for this treatment...
Approved
Investigational
Matched Synonyms: … 2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin …
Matched Iupac: … 2-methyl-1-({4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin …
Matched Description: … Food and Drug Administration on August 1, 2017. ... This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and ... First developed by Agios Pharmaceuticals and licensed to Celgene, enasidenib was approved by U.S. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-methyl-1-({4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin …
Matched Description: … Food and Drug Administration on August 1, 2017. ... This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and ... First developed by Agios Pharmaceuticals and licensed to Celgene, enasidenib was approved by U.S. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Triciribine phosphate
Investigational
Matched Synonyms: … 3-AMINO-1,5-DIHYDRO-5-METHYL-1-.BETA. …
Matched Iupac: … {[(2R,3S,4R,5R)-5-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … {[(2R,3S,4R,5R)-5-{5-amino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10- …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Morin
Experimental
Matched Synonyms: … 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-one …
Matched Categories: … Indicators and Reagents ... Heterocyclic Compounds, 1-Ring …
Matched Categories: … Indicators and Reagents ... Heterocyclic Compounds, 1-Ring …
Befiradol
Befiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia).
Investigational
Matched Synonyms: … (3-chloro-4-fluorophenyl)(4-fluoro-4-((((5-methylpyridin-2-yl)methyl)amino)methyl)piperidin-1-yl)methanone …
Matched Description: … Befiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and ... Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Befiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and ... Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia). …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
4-Carbamoyl-1-Beta-D-Ribofuranosyl-Imidazolium-5-Olate-5'-Phosphate
Experimental
Matched Name: … 4-Carbamoyl-1-Beta-D-Ribofuranosyl-Imidazolium-5-Olate-5'-Phosphate …
Matched Iupac: … 4-carbamoyl-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1H-imidazol …
Matched Iupac: … 4-carbamoyl-1-[(2R,3R,4S,5R)-5-[(hydrogen phosphonatooxy)methyl]-3,4-dihydroxyoxolan-2-yl]-1H-imidazol …
6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine
Experimental
Matched Name: … 6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine …
Matched Iupac: … 6-carbamimidoyl-N-[(1S)-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]naphthalene-2-carboxamide …
Matched Iupac: … 6-carbamimidoyl-N-[(1S)-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]naphthalene-2-carboxamide …
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. This compound belongs to the n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. It is known to target cathepsin K.
Experimental
Matched Name: … N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide …
Matched Iupac: … benzyl N-[(1S)-1-{[(3R)-1-cyanopyrrolidin-3-yl]carbamoyl}-3-methylbutyl]carbamate …
Matched Description: … This compound belongs to the n-acyl-alpha amino acids and derivatives. ... N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. …
Matched Iupac: … benzyl N-[(1S)-1-{[(3R)-1-cyanopyrrolidin-3-yl]carbamoyl}-3-methylbutyl]carbamate …
Matched Description: … This compound belongs to the n-acyl-alpha amino acids and derivatives. ... N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. …
(6,7-Difluoro-Quinazolin-4-Yl)-(1-Methyl-2,2-Diphenyl-Ethyl)-Amine
Experimental
Matched Name: … (6,7-Difluoro-Quinazolin-4-Yl)-(1-Methyl-2,2-Diphenyl-Ethyl)-Amine …
Matched Iupac: … N-[(2S)-1,1-diphenylpropan-2-yl]-6,7-difluoroquinazolin-4-amine …
Matched Iupac: … N-[(2S)-1,1-diphenylpropan-2-yl]-6,7-difluoroquinazolin-4-amine …
2'-(4-Dimethylaminophenyl)-5-(4-Methyl-1-Piperazinyl)-2,5'-Bi-Benzimidazole
Experimental
Matched Name: … 2'-(4-Dimethylaminophenyl)-5-(4-Methyl-1-Piperazinyl)-2,5'-Bi-Benzimidazole …
Matched Iupac: … N,N-dimethyl-4-{5-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1H-1,3-benzodiazol-2-yl}aniline …
Matched Iupac: … N,N-dimethyl-4-{5-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1H-1,3-benzodiazol-2-yl}aniline …
3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER
Experimental
Matched Name: … 3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER …
Matched Iupac: … 4-(ethoxycarbonyl)-3,5-dimethyl-1-phenyl-1H-pyrazol-2-ium …
Matched Iupac: … 4-(ethoxycarbonyl)-3,5-dimethyl-1-phenyl-1H-pyrazol-2-ium …
(R)-1-(4-(4-(Hydroxymethyl)-1,3,2-dioxaborolan-2-YL)phenyl)guanidine
Experimental
Matched Name: … (R)-1-(4-(4-(Hydroxymethyl)-1,3,2-dioxaborolan-2-YL)phenyl)guanidine …
Displaying drugs 3301 - 3325 of 4067 in total