Displaying drugs 3301 - 3325 of 3854 in total
OXI-4503
OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). In addition, however, preclinical data demonstrates...
Investigational
Matched Name: … OXI-4503 …
Matched Iupac: … [3-methoxy-2-(phosphonooxy)-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]phosphonic acid …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. ... (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor infiltrates, to …
Matched Salts name: … OXI-4503 dipotassium …
Matched Categories: … Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids …
Matched Iupac: … [3-methoxy-2-(phosphonooxy)-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]phosphonic acid …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. ... (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor infiltrates, to …
Matched Salts name: … OXI-4503 dipotassium …
Matched Categories: … Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids …
METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-ISOPROPYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE
Experimental
Matched Name: … METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-ISOPROPYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE …
Secobarbital
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Synonyms: … 5-allyl-5-(1-methylbutyl)barbituric acid …
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate ... derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. …
Matched Categories: … Hypnotics and Sedatives …
Enalapril
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Synonyms: … (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and ... Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the …
Matched Mixtures name: … ENALADIL-DUO ... ENALADIL DUO COMPRIMIDO ... Enalapril Maleate and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... enalapril and diuretics ... enalapril and nitrendipine …
Matched Products: … Dom-enalapril ... ENALAPRIL DOC …
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and ... Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the …
Matched Mixtures name: … ENALADIL-DUO ... ENALADIL DUO COMPRIMIDO ... Enalapril Maleate and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... enalapril and diuretics ... enalapril and nitrendipine …
Matched Products: … Dom-enalapril ... ENALAPRIL DOC …
Peginterferon alfa-2a
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Synonyms: … Pegylated interferon alpha-2a …
Matched Description: … development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Interferon alpha ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Interferon alpha ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE
Experimental
Matched Name: … METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE …
Simurosertib
Simurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors).
Investigational
Matched Synonyms: … 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one …
Matched Iupac: … 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one …
Matched Description: … is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and ... Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and …
Matched Iupac: … 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one …
Matched Description: … is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and ... Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and …
N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE
Experimental
Matched Name: … N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Matched Iupac: … N3-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Lirafugratinib
Investigational
Matched Synonyms: … Propenamide, N-[4-[4-amino-5-[3-fluoro-4-[(4-methyl-2-pyrimidinyl)oxy]phenyl]-7-methyl-7H-pyrrolo[2,3-d] ... N-(4-(4-amino-5-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- ... N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2- yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin …
Matched Iupac: … N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- …
Matched Salts name: … Lirafugratinib hydrochloride …
Matched Iupac: … N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- …
Matched Salts name: … Lirafugratinib hydrochloride …
Triciribine phosphate
Investigational
Matched Synonyms: … -D-RIBOFURANOSYL-1,4,5,6,8-PENTAAZAACENAPHTHYLENE 5'-(DIHYDROGEN PHOSPHATE) …
Matched Iupac: … pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10-pentaen-2-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … pentaazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,5,8,10-pentaen-2-yl}-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … domain) (synthetic human clone l19 scfv fragment) fusion protein with human tumor necrosis factor .alpha …
2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium
Experimental
Matched Name: … 2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium …
Matched Iupac: … 2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium …
Matched Iupac: … 2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium …
PF-04447943
PF-04447943 has been investigated for the treatment of Alzheimer's Disease.
Investigational
Matched Synonyms: … 4H-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-6-((3S,4S)-4-methyl-1-(2-pyrimidinylmethyl)-3-pyrrolidinyl ... Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d) …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-1-(oxan-4-yl)-1H,4H,5H-pyrazolo[3,4-d] …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-1-(oxan-4-yl)-1H,4H,5H-pyrazolo[3,4-d] …
Pregabalin
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Iupac: … (3S)-3-(aminomethyl)-5-methylhexanoic acid …
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended ... Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter …
Matched Mixtures name: … PRIKUL DUO …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Acyclic ... Amino Acids ... Carboxylic Acids …
Matched Products: … Dom-pregabalin ... PREGABALIN ACINO 25MG ... PREGABALIN ACINO 50MG …
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended ... Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter …
Matched Mixtures name: … PRIKUL DUO …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Acyclic ... Amino Acids ... Carboxylic Acids …
Matched Products: … Dom-pregabalin ... PREGABALIN ACINO 25MG ... PREGABALIN ACINO 50MG …
Edralbrutinib
Edralbrutinib is an orally available small molecule inhibitor of Bruton's tyrosine kinase.
Investigational
Matched Synonyms: … 2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1-oxo-2-butyn-1-yl)-3-pyrrolidinyl)-7h-pyrrolo(2,3-d) ... 7h-pyrrolo(2,3-d)pyridazin-7-one, 4-amino-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-1-((3r)-1-(1- …
Matched Iupac: … amino-1-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-3-[4-(2,6-difluorophenoxy)phenyl]-1H,6H,7H-pyrrolo[2,3-d] …
Matched Iupac: … amino-1-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-3-[4-(2,6-difluorophenoxy)phenyl]-1H,6H,7H-pyrrolo[2,3-d] …
Etoricoxib
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Synonyms: … 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine …
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and ... of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid …
Matched Salts name: … Etoricoxib hydrochloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORICOXIB DOC GENERICI …
Matched Description: … of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and ... of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid …
Matched Salts name: … Etoricoxib hydrochloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ETORICOXIB DOC GENERICI …
2-(3,4-Dihydro-3-Oxo-2h-Benzo[B][1,4]Thiazin-2-Yl)-N-Hydroxyacetamide
Experimental
Matched Name: … 2-(3,4-Dihydro-3-Oxo-2h-Benzo[B][1,4]Thiazin-2-Yl)-N-Hydroxyacetamide …
Elinzanetant
Elinzanetant is under investigation in clinical trial NCT05099159 (A Study to Learn More About How Well Elinzanetant Works and How Safe It Is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 26 Weeks in Women Who Have Been Through the Menopause (OASIS-2)).
Investigational
Matched Synonyms: … .,.alpha. ... methylphenyl)-6-((7s,9as)-hexahydro-7-(hydroxymethyl)pyrazino(2,1-c)(1,4)oxazin-8(1h)-yl)-3-pyridinyl)-n,.alpha …
Matched Description: … investigation in clinical trial NCT05099159 (A Study to Learn More About How Well Elinzanetant Works and …
Matched Description: … investigation in clinical trial NCT05099159 (A Study to Learn More About How Well Elinzanetant Works and …
Ibrutinib
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Synonyms: … 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... [A32299] Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in November 2013 ... [L45894] Ibrutinib was approved by the EMA in October 2014 [L45884] and by Health Canada in November …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
2'-deoxythioguanosine
Investigational
Matched Synonyms: … -d-erythro-pentofuranosyl)-6-mercaptopurine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
S-55746
Investigational
Matched Synonyms: … (S)-N-(4-hydroxyphenyl)-3-(6-(3-(morpholinomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)benzo(d) …
2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Thiopyran-3-Carboxylic Acid
Experimental
Matched Name: … 2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Thiopyran-3-Carboxylic Acid …
Matched Iupac: … 2-(carboxyformamido)-4H,5H,7H-thieno[2,3-c]thiopyran-3-carboxylic acid …
Matched Iupac: … 2-(carboxyformamido)-4H,5H,7H-thieno[2,3-c]thiopyran-3-carboxylic acid …
4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid
Experimental
Matched Name: … 4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid …
Matched Iupac: … 4-{[1-benzyl-3-(carbamoylmethyl)-2-methyl-1H-indol-5-yl]oxy}butanoic acid …
Matched Iupac: … 4-{[1-benzyl-3-(carbamoylmethyl)-2-methyl-1H-indol-5-yl]oxy}butanoic acid …
2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid
Experimental
Matched Name: … 2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid …
Matched Iupac: … 2-(carboxyformamido)-4H,5H,7H-thieno[2,3-c]pyran-3-carboxylic acid …
Matched Iupac: … 2-(carboxyformamido)-4H,5H,7H-thieno[2,3-c]pyran-3-carboxylic acid …
(2s)-2-[(2,4-Dichloro-Benzoyl)-(3-Trifluoromethyl-Benzyl)-Amino]-3-Phenyl-Propionic Acid
Experimental
Matched Name: … (2s)-2-[(2,4-Dichloro-Benzoyl)-(3-Trifluoromethyl-Benzyl)-Amino]-3-Phenyl-Propionic Acid …
Matched Iupac: … (2S)-2-[1-(2,4-dichlorophenyl)-N-{[3-(trifluoromethyl)phenyl]methyl}formamido]-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-[1-(2,4-dichlorophenyl)-N-{[3-(trifluoromethyl)phenyl]methyl}formamido]-3-phenylpropanoic acid …
Displaying drugs 3301 - 3325 of 3854 in total