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Displaying drugs 3551 - 3575 of 9809 in total

(5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE

Experimental
Matched Name: … (5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE …
Matched Iupac: … (5E)-14-chloro-15,17-dihydroxy-1,3,4,7,8,9,10,11,12,13-decahydro-2-benzoxacyclopentadecine-1,12-dione …

Ezeprogind

Investigational
Matched Synonyms: … N-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1h-benzo(d)imidazol-2-amine ... 1,4-piperazinedipropanamine, n'-1h-benzimidazol-2-yl-n,n-bis(2-methylpropyl)- ... 1,4-piperazinedipropanamine, n4-1h-benzimidazol-2-yl-n1,n1-bis(2-methylpropyl)- …
Matched Iupac: … N-[3-(4-{3-[bis(2-methylpropyl)amino]propyl}piperazin-1-yl)propyl]-1H-1,3-benzodiazol-2-amine …

(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE

Experimental
Matched Name: … (5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE …
Matched Iupac: … (5E)-12-chloro-13,15-dihydroxy-1,3,4,7,8,9,10,11-octahydro-2-benzoxacyclotridecine-1,10-dione …

Epicatechin

Epicatechin has been used in trials studying the treatment of Pre-diabetes.
Investigational
Matched Iupac: … (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

TT-232

Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma).
Investigational
Matched Synonyms: … D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2 (disulfide bridge: 2-6) …
Matched Iupac: … (2S,3R)-2-{[(4R,7S,10R,13S,16R)-16-[(2R)-2-amino-3-phenylpropanamido]-7-(4-aminobutyl)-13-[(4-hydroxyphenyl ... )methyl]-10-[(1H-indol-3-yl)methyl]-6,9,12,15-tetraoxo-1,2-dithia-5,8,11,14-tetraazacycloheptadecan-4 …
Matched Salts name: … D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2 (disulfide bridge: 2-6) acetate …

Dimethylphthalate

Experimental
Matched Iupac: … 1,2-dimethyl benzene-1,2-dicarboxylate …

Dibutylphthalate

Experimental
Matched Iupac: … 1,2-dibutyl benzene-1,2-dicarboxylate …

(6,7-Difluoro-Quinazolin-4-Yl)-(1-Methyl-2,2-Diphenyl-Ethyl)-Amine

Experimental
Matched Name: … (6,7-Difluoro-Quinazolin-4-Yl)-(1-Methyl-2,2-Diphenyl-Ethyl)-Amine …
Matched Iupac: … N-[(2S)-1,1-diphenylpropan-2-yl]-6,7-difluoroquinazolin-4-amine …

N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide

Experimental
Matched Name: … N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide …
Matched Iupac: … N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-fluorobenzamide …

Apigenin

Experimental
Matched Iupac: … 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL

Experimental
Matched Name: … CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL …
Matched Iupac: … (1R,2S)-2-amino-1,2,3,4-tetrahydronaphthalen-1-ol …

Mardepodect

Investigational
Matched Synonyms: … 2-[4-(1-Methyl-4-pyridin-4-yl-lH-pyrazol-3-yl)-phenoxymethyl]-quinoline succinic acid …
Matched Iupac: … 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline …
Matched Salts cas: … 1037309-45-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

XL281

XL281 is a novel anticancer compound designed to potently inhibit the RAS/RAF/MEK/ERK signaling pathway. Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer. XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which...
Investigational
Matched Description: … XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which is activated in 60 …

6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

Experimental

1alpha,24S-Dihydroxyvitamin D2

LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol. It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol,...
Investigational
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-5-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro …

M-701

M-701 is a recombinant anti-EpCAM/CD3 bispecific antibody.
Investigational

Birabresib

Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).
Investigational
Matched Synonyms: … 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thienol[3,2,-f]-[1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl …
Matched Iupac: … 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 …

BQ-123

BQ-123 has been investigated for the basic science and treatment of Coronary Artery Disease, Aorto-coronary Bypass Grafting, and ST-Elevation Myocardial Infarction.
Investigational
Matched Iupac: … yl)-hexadecahydro-1H-pyrrolo[1,2-a]1,4,7,10,13-pentaazacyclopentadecan-12-yl]acetic acid ... 2-[(3R,6S,9R,12R,17aS)-9-[(1H-indol-3-yl)methyl]-6-(2-methylpropyl)-1,4,7,10,13-pentaoxo-3-(propan-2- …
Matched Salts cas: … 136655-57-7 …

rAAV9-rsATP7A

A recombinant adeno-associated viral vector gene therapy under investigation for the treatment of Menkes disease.
Investigational

Saprisartan

Saprisartan is an AT1 receptor antagonist. It is based on medications of losartan's prototypical chemical structure. The mode of (functional) AT1 receptor antagonism has been characterized as insurmountable/noncompetitive for saprisartan. It is very likely that slow dissociation kinetics from the AT1 receptor underlie insurmountable antagonism .
Experimental
Matched Iupac: … 1-({3-bromo-2-[2-(trifluoromethanesulfonamido)phenyl]-1-benzofuran-5-yl}methyl)-4-cyclopropyl-2-ethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 1 Receptor Blockers …

AAV9/MFSD8

AAV9/MFSD8 is a gene therapy developed by Neurogene Inc. It is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human CLN7/MFSD8 gene for expression of active human major facilitator superfamily domain containing 8. It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7.
Investigational
Matched Description: … It was investigated for the treatment of neuronal ceroid lipofuscinosis type 7. …

Dimefline

Experimental
Matched Iupac: … 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …

(1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE

Experimental
Matched Name: … (1S)-1-CYCLOPROPYL-2-[(2S)-4-(2,5-DIFLUOROPHENYL)-2-PHENYL-2,5-DIHYDRO-1H-PYRROL-1-YL]-2-OXOETHANAMINE …
Matched Iupac: … (2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]ethan-1 …

TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL

Experimental
Matched Name: … TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL …
Matched Iupac: … (1S,2S)-2-amino-1,2,3,4-tetrahydronaphthalen-1-ol …

SUCCINIC ACID MONO-(13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL) ESTER

Experimental
Matched Iupac: … [a]phenanthren-1-yl]oxy}-4-oxobutanoic acid ... 4-{[(1R,3aS,3bR,9aR,9bS,11aS)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Displaying drugs 3551 - 3575 of 9809 in total