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Displaying drugs 3551 - 3575 of 4257 in total
Experimental
Matched Name: … N-(2,3,4,5,6-Pentaflouro-Benzyl)-4-Sulfamoyl-Benzamide …
Matched Iupac: … N-[(2,3,4,5,6-pentafluorophenyl)methyl]-4-sulfamoylbenzamide …
Experimental
Matched Name: … S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea …
Matched Iupac: … (E)-N'-[4-(trifluoromethyl)phenyl](ethylsulfanyl)methanimidamide …
Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(2,5-Difluorophenyl)Methyl]-Benzamide …
Matched Iupac: … N-[(2,5-difluorophenyl)methyl]-4-sulfamoylbenzamide …
Experimental
Matched Name: … (3s)-3,4-Di-N-Hexanoyloxybutyl-1-Phosphocholine …
Experimental
Matched Name: … D-leucyl-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-4-methylpentanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Experimental
Matched Name: … D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-4-methylpentanoyl]-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide …
Experimental
Matched Name: … D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-fluorophenyl)methyl]pyrrolidine-2-carboxamide …
Experimental
Matched Name: … 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE …
Matched Iupac: … 4-phenoxy-N-[(pyridin-2-yl)methyl]benzamide …
Experimental
Matched Name: … N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide …
Matched Iupac: … N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide …
Experimental
Matched Name: … N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide …
Matched Iupac: … 2-{[1,1'-biphenyl]-4-sulfonamido}-N-oxoacetamide …
Experimental
Matched Name: … N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide …
Matched Iupac: … N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide …
Experimental
Matched Name: … N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE …
Matched Iupac: … N-[4-(phenylamino)quinazolin-6-yl]prop-2-enamide …
Experimental
Matched Name: … 4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE …
Experimental
Matched Name: … [N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE …
Matched Iupac: … [(R)-{[(benzyloxy)carbonyl]amino}(4-carbamimidoylphenyl)methyl]phosphonic acid
Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).
Investigational
Matched Synonyms: … 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin ... BENZAMIDE, 5-(4-CYCLOPROPYL-1H-IMIDAZOL-1-YL)-2-FLUORO-4-METHYL-N-(6-(4-(1-METHYLETHYL)-4H-1,2,4-TRIAZOL ... 5-(4-Cyclopropyl-1H-imidazol-l-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide …
Matched Iupac: … 5-(4-cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin …
Matched Description: … Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib ... in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis). …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Experimental
Matched Synonyms: … (2R)-2-Cyclohexyl-2-(diaminomethylideneamino)-N-[2-[4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin …
Matched Iupac: … (2R)-2-cyclohexyl-2-[(diaminomethylidene)amino]-N-(2-{4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin …
Adherex's biotechnology compound, ADH-1, targets N-cadherin, a protein present on certain tumor cells and established tumor blood vessels. ADH-1 is currently in clinical development in a combination program with a range of chemotherapeutic agents to investigate the synergistic effects noted in our preclinical models. At the end of 2006, the...
Investigational
Matched Synonyms: … l-cysteinamide, n-acetyl-l-cysteinyl-l-histidyl-l-alanyl-l-valyl-, cyclic (1-5)-disulfide …
Matched Description: … As many tumors become more aggressive, invasive, and malignant, researchers have found that N-cadherin ... As tumors progress to become higher grade, invasive and more metastatic, the frequency of N-cadherin ... and established tumor blood vessels. …
Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. In patients with Gaucher disease, the accumulation of glucosylceramide leads to...
Approved
Investigational
Matched Synonyms: … N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide …
Matched Iupac: … N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide …
Matched Description: … , an enzyme that converts glucosylceramide into glucose and ceramide. ... This leads to complications such as anemia and thrombocytopenia. ... glucosylceramide leads to the formation of Gaucher cells that infiltrate the liver, spleen, bone marrow and
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Investigational
Matched Synonyms: … N-[(1R,2R)-2-(3-chloro-4-cyclopropoxyphenyl)-2-hydroxy-1-(pyrrolidinylmethyl)ethyl]-2-(6-chloro(2-naphthyl …
Sulfamoxole is an antibacterial in the sulfonamide class.
Experimental
Matched Synonyms: … N1-(4,5-Dimethyl-2-oxazolyl)sulfanilamide ... N(sup 1)-(4,5-Dimethyl-2-oxazolyl)sulfanilamide ... 4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide …
Matched Iupac: … 4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzene-1-sulfonamide …
Matched Categories: … Sulfonamides and trimethoprim ... sulfamoxole and trimethoprim …
Edecesertib is under investigation in clinical trial NCT05629208 (Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)).
Investigational
Matched Synonyms: … 3-Pyridinecarboxamide, 4-[[(1R)-1-cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2 ... 4-{[(1R)-1-cyanoethyl]amino}-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3- methylbutyl …
Experimental
Matched Name: … 2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid
Matched Iupac: … -2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-5-phosphonopent-3-enoic acid
Experimental
Matched Name: … (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid
Matched Iupac: … (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid
Experimental
Matched Name: … Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid
Matched Iupac: … fluoro-4-[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetamido]benzoic acid
Experimental
Matched Name: … 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID
Matched Iupac: … 4-(5-{[(5Z)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid
Displaying drugs 3551 - 3575 of 4257 in total