Displaying drugs 3576 - 3600 of 4147 in total
4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
Experimental
Matched Name: … 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE …
Matched Iupac: … 4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine …
Matched Iupac: … 4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine …
3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine)
Investigational
Matched Synonyms: … 3-(4-(8-fluoroquinoline)imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Matched Name: … 3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Matched Name: … 3-(4-(8-Fluoroquinoline) imidazole(1,2-a)pyridine-7-(1-phenyl-4-(1-(4-methyl piperazine) …
Decitabine
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … DAC ... 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one …
Matched Description: … integrate into cellular DNA and inhibit the action of DNA methyltransferases, leading to global hypomethylation ... presentation, including neutropenia and thrombocytopenia. ... syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Description: … integrate into cellular DNA and inhibit the action of DNA methyltransferases, leading to global hypomethylation ... presentation, including neutropenia and thrombocytopenia. ... syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
4-Methoxyamphetamine
Experimental
Illicit
Matched Synonyms: … D,L-p-methoxyamphetamine …
Matched Categories: … Adrenergic alpha-Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Adrenergic alpha-1 Receptor Agonists …
Matched Categories: … Adrenergic alpha-Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Adrenergic alpha-1 Receptor Agonists …
Palbociclib
Palbociclib is a piperazine pyridopyrimidine that acts in the cell cycle machinery. It is a second generation cyclin-dependent kinase inhibitor selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as...
Approved
Investigational
Matched Synonyms: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H) …
Matched Iupac: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin …
Matched Description: … to its favorable physical and pharmaceutical properties. ... electronic health records demonstrating safety and clinical efficacy. ... on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin …
Matched Description: … to its favorable physical and pharmaceutical properties. ... electronic health records demonstrating safety and clinical efficacy. ... on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Simurosertib
Simurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumors).
Investigational
Matched Synonyms: … 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one …
Matched Iupac: … 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one …
Matched Description: … is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and ... Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and …
Matched Iupac: … 2-[(2S)-1-azabicyclo[2.2.2]octan-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)-3H,4H-thieno[3,2-d]pyrimidin-4-one …
Matched Description: … is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and ... Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and …
Leukotriene C4
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and...
Experimental
Investigational
Matched Synonyms: … ,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine …
Matched Iupac: … -carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid …
Matched Description: … It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized ... The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular …
Matched Categories: … Fatty Acids ... Arachidonic Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Iupac: … -carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]sulfanyl}-5-hydroxyicosa-7,9,11,14-tetraenoic acid …
Matched Description: … It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized ... The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular …
Matched Categories: … Fatty Acids ... Arachidonic Acids ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Enalapril
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Synonyms: … (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … renal reabsorption of sodium ions in the kidneys. ... fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and …
Matched Mixtures name: … ENALADIL-DUO ... ENALADIL DUO COMPRIMIDO ... Enalapril Maleate and Hydrochlorothiazide …
Matched Salts name: … Enalapril sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... enalapril and diuretics ... enalapril and nitrendipine …
Matched Products: … Dom-enalapril ... ENALAPRIL DOC …
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … renal reabsorption of sodium ions in the kidneys. ... fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and …
Matched Mixtures name: … ENALADIL-DUO ... ENALADIL DUO COMPRIMIDO ... Enalapril Maleate and Hydrochlorothiazide …
Matched Salts name: … Enalapril sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... enalapril and diuretics ... enalapril and nitrendipine …
Matched Products: … Dom-enalapril ... ENALAPRIL DOC …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Acetan HCT Tablet 50/12.5mg ... Acetan HCT Tablet 100mg/25mg ... Hyzaar DS …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … Acetan Tablet 50mg ... Acetan Tablet 100mg ... DUP 753 …
Matched Mixtures name: … Acetan HCT Tablet 50/12.5mg ... Acetan HCT Tablet 100mg/25mg ... Hyzaar DS …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … Acetan Tablet 50mg ... Acetan Tablet 100mg ... DUP 753 …
Betula populifolia pollen
Betula populifolia pollen is the pollen of the Betula populifolia plant. Betula populifolia pollen is mainly used in allergenic testing.
Approved
Matched Name: … Betula populifolia pollen …
Matched Description: … Betula populifolia pollen is the pollen of the Betula populifolia plant. ... Betula populifolia pollen is mainly used in allergenic testing. …
Matched Description: … Betula populifolia pollen is the pollen of the Betula populifolia plant. ... Betula populifolia pollen is mainly used in allergenic testing. …
Betula papyrifera pollen
Betula papyrifera pollen is the pollen of the Betula papyrifera plant. Betula papyrifera pollen is mainly used in allergenic testing.
Approved
Matched Name: … Betula papyrifera pollen …
Matched Description: … Betula papyrifera pollen is the pollen of the Betula papyrifera plant. ... Betula papyrifera pollen is mainly used in allergenic testing. …
Matched Description: … Betula papyrifera pollen is the pollen of the Betula papyrifera plant. ... Betula papyrifera pollen is mainly used in allergenic testing. …
Betula alleghaniensis pollen
Betula alleghaniensis pollen is the pollen of the Betula alleghaniensis plant. Betula alleghaniensis pollen is mainly used in allergenic testing.
Approved
Matched Name: … Betula alleghaniensis pollen …
Matched Description: … Betula alleghaniensis pollen is the pollen of the Betula alleghaniensis plant. ... Betula alleghaniensis pollen is mainly used in allergenic testing. …
Matched Description: … Betula alleghaniensis pollen is the pollen of the Betula alleghaniensis plant. ... Betula alleghaniensis pollen is mainly used in allergenic testing. …
Dimethylaminomicheliolide
Investigational
Matched Synonyms: … 11.BETA.,13-DIHYDRO-13-(DIMETHYLAMINO)MICHELIOLIDE …
Peginterferon alfa-2a
Peginterferon alfa-2a is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Investigational
Matched Synonyms: … Pegylated interferon alpha-2a …
Matched Description: … development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Interferon alpha ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … development of endocrine and autoimmune disorders, retinopathies, cardiovascular and neuropsychiatric ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... the janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Interferon alpha ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
OXI-4503
OXI-4503 is investigated in clinical trials for treating cancer/tumors. OXI-4503 is a solid. OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular disrupting agent (VDA). In addition, however, preclinical data demonstrates...
Investigational
Matched Name: … OXI-4503 …
Matched Iupac: … [3-methoxy-2-(phosphonooxy)-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]phosphonic acid …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. ... (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor infiltrates, to …
Matched Salts name: … OXI-4503 dipotassium …
Matched Categories: … Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids …
Matched Iupac: … [3-methoxy-2-(phosphonooxy)-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]phosphonic acid …
Matched Description: … OXI-4503 (combretastatin A1 di-phosphate / CA1P) is a unique and highly potent, dual-mechanism vascular ... OXI-4503 blocks and destroys tumor vasculature, resulting in extensive tumor cell death and necrosis. ... (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor infiltrates, to …
Matched Salts name: … OXI-4503 dipotassium …
Matched Categories: … Acids ... Acids, Noncarboxylic ... Phosphoric Acids ... Phosphorus Acids …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Lirafugratinib
Investigational
Matched Synonyms: … Propenamide, N-[4-[4-amino-5-[3-fluoro-4-[(4-methyl-2-pyrimidinyl)oxy]phenyl]-7-methyl-7H-pyrrolo[2,3-d] ... N-(4-(4-amino-5-(3-fluoro-4-((4-methylpyrimidin-2-yl)oxy)phenyl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- ... N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2- yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin …
Matched Iupac: … N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- …
Matched Salts name: … Lirafugratinib hydrochloride …
Matched Iupac: … N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- …
Matched Salts name: … Lirafugratinib hydrochloride …
Onfekafusp alfa
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … domain) (synthetic human clone l19 scfv fragment) fusion protein with human tumor necrosis factor .alpha …
Tenofovir disoproxil
Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Mixtures name: … INMUNOVIR DUO ... EMTRICITABINA/TENOFOVIR DISOPROXIL KRKA D.D. ... EMTRICITABINA/TENOFOVIR DISOPROXIL KRKA D.D. …
Matched Categories: … Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... tenofovir disoproxil and emtricitabine ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … TENOFOVIR DIS BETA 245MG ... TENOFOVIR DISOPROXIL DR. REDDY'S ... TENOFOVIR DISOPROXIL DOC GENERICI …
Matched Categories: … Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors ... tenofovir disoproxil and emtricitabine ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … TENOFOVIR DIS BETA 245MG ... TENOFOVIR DISOPROXIL DR. REDDY'S ... TENOFOVIR DISOPROXIL DOC GENERICI …
3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
Experimental
Matched Name: … 3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester …
(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
Experimental
Matched Name: … (1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid …
Matched Iupac: … 2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid …
Matched Iupac: … 2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid …
3-[(1-Amino-2-Carboxy-Ethyl)-Hydroxy-Phosphinoyl]-2-Methyl-Propionic Acid
Experimental
Matched Name: … 3-[(1-Amino-2-Carboxy-Ethyl)-Hydroxy-Phosphinoyl]-2-Methyl-Propionic Acid …
Matched Iupac: … (2S)-3-{[(1R)-1-amino-2-carboxyethyl](hydroxy)phosphoryl}-2-methylpropanoic acid …
Matched Iupac: … (2S)-3-{[(1R)-1-amino-2-carboxyethyl](hydroxy)phosphoryl}-2-methylpropanoic acid …
(3,4,5-Trihydroxy-6-Hydroxymethyl-Tetrahydro-Pyran-2-Yl)-Phosphoramidic Acid Dimethyl Ester
Experimental
Matched Name: … (3,4,5-Trihydroxy-6-Hydroxymethyl-Tetrahydro-Pyran-2-Yl)-Phosphoramidic Acid Dimethyl Ester …
1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester
Experimental
Matched Name: … 1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester …
7-{2,6-DICHLORO-4-[3-(2-CHLORO-BENZOYL)-UREIDO]-PHENOXY}-HEPTANOIC ACID
Experimental
Matched Name: … 7-{2,6-DICHLORO-4-[3-(2-CHLORO-BENZOYL)-UREIDO]-PHENOXY}-HEPTANOIC ACID …
Matched Iupac: … 7-[2,6-dichloro-4-({[(2-chlorophenyl)formamido]carbonyl}amino)phenoxy]heptanoic acid …
Matched Iupac: … 7-[2,6-dichloro-4-({[(2-chlorophenyl)formamido]carbonyl}amino)phenoxy]heptanoic acid …
Displaying drugs 3576 - 3600 of 4147 in total