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Displaying drugs 3601 - 3625 of 9026 in total
Peptimmune’s lead product GT 389-255, is a novel lipase inhibitor and fat binding hydrogel polymer conjugate for the treatment of obesity which has completed single and multiple ascending dose (SAD and MAD) Phase I trials. It is expected to block fat absorption with fewer side effects than currently marketed lipase...
Investigational
TORL-2307 is a humanized immunoglobulin G1 (IgG1) monoclonal antibody (mAb) directed against claudin 18.2 (CLDN18.2) being investigated for the treatment of gastric and pancreatic cancer.
Investigational
Matched Name: … TORL-2-307 …
Sulopenem is under investigation in clinical trial NCT03357614 (Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults).
Investigational
Matched Iupac: … (1R,3S)-3-{[(5R,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-en-3-yl] …
Investigational
Somatropin pegol is under investigation in clinical trial NCT00715689 (Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083).
Investigational
Experimental
Matched Iupac: … iron(3+) ion trihydroxide …
Matched Products: … FERIFER 100 MG/5 ML ORAL COZELTI ICEREN KAŞIK, 20 ADET …
Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20)-positive DLBCL Patients).
Investigational
Matched Description: … Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated Cd20(cluster of Differentiation Antigen 20
Investigational
Matched Synonyms: … (2-thienyl)-L-alanylglycyl-L-leucyl-2-amino-4-(methylsulfonyl)-, (2S)- ... tetraazacyclododec-1-yl]acetyl]-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-3- …
Matched Iupac: … (225Ac)actinium(3+) 2-[4-({[(2S)-1-[(2S)-2-{[(2S)-6-amino-1-[(2S)-2-{[(1S)-3-carbamoyl-1-{[(1S)-3-carbamoyl ... -1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-{[(1S)-1-carbamoyl-3-methanesulfonylpropyl]carbamoyl}-3-methylbutyl]carbamoyl ... }methyl)carbamoyl]-2-(thiophen-2-yl)ethyl]carbamoyl}-2-phenylethyl]carbamoyl}propyl]carbamoyl}propyl] ... carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}pyrrolidin-1-yl]-5-carbamimidamido-1-oxopentan-2
ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of chronic hepatitis C virus (HCV) infection. ANA971 is a prodrug designed to improve the oral bioavailability of isatoribine. ANA971 resulted in higher levels of isatoribine in the blood than were present after...
Investigational
Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Investigational
Matched Synonyms: … BENZOIC ACID, 3,4,5-TRIHYDROXY-, (2R,3R)-3,4-DIHYDRO-5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-2H-1-BENZOPYRAN ... -3-YL ESTER ... (-)-Epigallocatechin 3-gallate …
Matched Iupac: … (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Investigational
Investigational
Matched Synonyms: … 1-piperazinecarboxamide, 4-methyl-n-((1s)-2-oxo-2-(((1s)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen ... 1-piperazinecarboxamide, 4-methyl-n-((1s)-2-oxo-2-(((1s)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propenyl ... 4-methylpiperazine-1-carboxylic acid [1-(3-benzenesufonyl-1-phenethylallyl-carbamoyl)-2-phenylethyl] …
Matched Iupac: … (2S)-N-[(1E,3S)-1-(benzenesulfonyl)-5-phenylpent-1-en-3-yl]-2-{[(E)-4-methylpiperazine-1-carbonyl]amino ... }-3-phenylpropanamide …
MB07803 is a second generation gluconeogenesis inhibitor for the treatment of type 2 diabetes. It is designed to block the metabolic pathway in the liver that is responsible for producing glucose.
Investigational
Matched Iupac: … ethyl 2-[({5-[2-amino-5-(2,2-dimethylpropanoyl)-1,3-thiazol-4-yl]furan-2-yl}[(1-ethoxy-2-methyl-1-oxopropan ... -2-yl)amino]phosphoryl)amino]-2-methylpropanoate …
Matched Description: … MB07803 is a second generation gluconeogenesis inhibitor for the treatment of type 2 diabetes. …
MediGene's newly acquired drug candidates MBT-0312 aim at a novel method of cancer therapy by "starving out" tumors.
Investigational
AZD0424 has been used in trials studying the treatment of Advanced Solid Tumours.
Investigational
Matched Iupac: … 1-[4-(2-{[4-({6-chloro-2H-[1,3]dioxolo[4,5-b]pyridin-7-yl}amino)-5-(propan-2-yloxy)quinazolin-7-yl]oxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GDC-0927 is under investigation in clinical trial NCT02316509 (A Study of GDC-0927 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer).
Investigational
Matched Iupac: … (2S)-2-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6- …
VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).
Investigational
Matched Iupac: … (2S)-3-[4-(2-fluoroethoxy)phenyl]-2-[(2S)-3-methyl-2-(4-{[(2-sulfamoyl-1,3-benzothiazol-6-yl)oxy]methyl …
SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients).
Investigational
YS-ON-001 is a combination of an inactivated purified rabies virus (IPRV) and the PIKA adjuvant (Poly I:C, kanamycin and calcium).
Investigational
TASO-001 is a transforming growth factor (TGF)-beta 2 specific antisense oligodeoxynucleotide.
Investigational
Matched Description: … TASO-001 is a transforming growth factor (TGF)-beta 2 specific antisense oligodeoxynucleotide. …
Investigational
EXOB-001 consists of extracellular vesicles derived from cultured human umbilical cord mesenchymal stromal cells.
Investigational
CALY-002 is a humanized monoclonal antibody targeting interleukin-15.
Investigational
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Displaying drugs 3601 - 3625 of 9026 in total