Displaying drugs 3601 - 3625 of 3952 in total
Ebvaciclib
Ebvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).
Investigational
Matched Synonyms: … )-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- (methylsulfonyl)piperidin-4-yl) amino)pyrido(2,3-d) ... Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- …
AR-42
AR-42 has been used in trials studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and Vestibular Schwannoma, among others.
Investigational
Matched Synonyms: … BENZENEACETAMIDE, N-(4-((HYDROXYAMINO)CARBONYL)PHENYL)-.ALPHA.-(1-METHYLETHYL)-, (.ALPHA.S)- …
Matched Description: … studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and …
Matched Description: … studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and …
Entacapone
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Synonyms: … (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … LEVO C/E BETA50/12.5/200 ... LEVO C/E BETA50/12.5/200 ... LEVO C/E BETA50/12.5/200 …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … LEVO C/E BETA50/12.5/200 ... LEVO C/E BETA50/12.5/200 ... LEVO C/E BETA50/12.5/200 …
2-(3,4-Dihydro-3-Oxo-2h-Benzo[B][1,4]Thiazin-2-Yl)-N-Hydroxyacetamide
Experimental
Matched Name: … 2-(3,4-Dihydro-3-Oxo-2h-Benzo[B][1,4]Thiazin-2-Yl)-N-Hydroxyacetamide …
METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE
Experimental
Matched Name: … METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-METHYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE …
Clervonafusp alfa
Investigational
Matched Synonyms: … fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human lysosomal .alpha ... Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952-lysosomal .alpha …
METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-ISOPROPYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE
Experimental
Matched Name: … METHYL N-[(2S,3R)-3-AMINO-2-HYDROXY-3-(4-ISOPROPYLPHENYL)PROPANOYL]-D-ALANYL-D-LEUCINATE …
N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE
Experimental
Matched Name: … N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Matched Iupac: … N3-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine …
Doxifluridine
Doxifluridine has been investigated for the treatment of Stomach Cancer.
Investigational
Matched Synonyms: … 1-(β-D-5-desoxyribofuranoxyl)-5-fluoruracil …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Fluorouracil and prodrugs …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Fluorouracil and prodrugs …
Xenon Xe-129
Hyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance imaging (MRI). Lung MRIs are challenging due to the low proton density of this tissue, as well as the presence of artifacts due to respiration and cardiovascular pulsation movement and air–tissue interfaces.[A255178,A255183] The use of hyperpolarized...
Approved
Matched Synonyms: … Xenon, isotope of mass 129m(8.88 d) …
Matched Description: … due to respiration and cardiovascular pulsation movement and air–tissue interfaces. ... [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile ... [A255178] Xe-129 has a lower cost, and adverse effects are normally resolved shortly after administration …
Matched Description: … due to respiration and cardiovascular pulsation movement and air–tissue interfaces. ... [Helium-3] (He-3) is the one most commonly used due to its strong signal and favorable safety profile ... [A255178] Xe-129 has a lower cost, and adverse effects are normally resolved shortly after administration …
BR101801
Experimental
Matched Synonyms: … 4-[[(1S)-1-(4,8-dichloro-1-oxo-2-phenylisoquinolin-3-yl)ethyl]amino]-8H-pyrido[2,3-d]pyrimidin-5-one …
BCX9250
Investigational
Matched Synonyms: … (S)-1-(4-(1-(3,4,5-trimethyloxyphenyl)-1H-imidazol-4-ylamino)thieno[2,3-d]pyrimidin-2-yl)pyrrolidine- …
4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-Fluoro-Phenyl)-3-(3-Chloro-2-Fluoro-Phenyl)-4-Cyano-5-(2,2-Dimethyl-Propyl)-Pyrrolidine-2-Carbonyl]-Amino}-3-Methoxy-Benzoic Acid
Experimental
Matched Name: … Chloro-2-Fluoro-Phenyl)-4-Cyano-5-(2,2-Dimethyl-Propyl)-Pyrrolidine-2-Carbonyl]-Amino}-3-Methoxy-Benzoic Acid …
Phenoxyethanol
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Synonyms: … beta-Hydroxyethyl phenyl ether …
Matched Description: … It is produced by reacting phenol (EU) and ethylene oxide (EU) at a high temperature and pressure. ... is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and ... It is both naturally found and manufactured synthetically. …
Matched Mixtures name: … Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, Lösung …
Matched Description: … It is produced by reacting phenol (EU) and ethylene oxide (EU) at a high temperature and pressure. ... is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and ... It is both naturally found and manufactured synthetically. …
Matched Mixtures name: … Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, Lösung …
Ochromycinone
Ochromycinone is under investigation in clinical trial NCT01047943 (STA-21 Topical Efficacy on Psoriasis).
Investigational
Matched Synonyms: … (3s)-3.beta.-methyl-8-hydroxy-1,2,3,4,7,12-hexahydrobenzo(a)anthracene-1,7,12-trione …
Cemdomespib
Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)).
Investigational
Matched Synonyms: … Acetamide, n-(2-(5-((6-deoxy-5-c-methyl-4-o-methyl-.alpha. …
Olanzapine
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility ... and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Olanzapine hydrochloride …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines ... Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … MARATHON D ... Dom-olanzapine ... OLANZAPINA DOC …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Olanzapine hydrochloride …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines ... Dopamine D2 Receptor Antagonists ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … MARATHON D ... Dom-olanzapine ... OLANZAPINA DOC …
Fimepinostat
Fimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Investigational
Matched Synonyms: … 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin ... N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Matched Iupac: … N-hydroxy-2-({[2-(6-methoxypyridin-3-yl)-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}(methyl …
Matched Description: … been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and …
Futibatinib
Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and survival. FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed...
Approved
Investigational
Matched Synonyms: … 1-((3S)-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo(3, 4-d) pyrimidin-1-yl)-1-pyrrolidinyl) ... 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl] …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and ... FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated ... FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and ... FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated ... FGFR signalling pathways are observed in some cancers such as cholangiocarcinoma and urothelial malignancies …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
H3B-8800
H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no such preferential targeting . H3B-8800 was granted orphan drug status by the FDA in August 2017 and...
Investigational
Matched Synonyms: … 1-PIPERAZINECARBOXYLIC ACID, 4-METHYL-, (2S,3S,4E,6S,7R,10R)-7,10-DIHYDROXY-3,7-DIMETHYL-2-((1E,3E,5R …
Matched Description: … of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551]. ... H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment …
Matched Description: … of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551]. ... H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment …
Rasagiline
Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Approved
Matched Description: … Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's …
Matched Categories: … Monoamine Oxidase Inhibitors ... Monoamine Oxidase B Inhibitors …
Matched Products: … RASAGILIN BETA 1 MG ... RASAGILINA DOC GENERICI …
Matched Categories: … Monoamine Oxidase Inhibitors ... Monoamine Oxidase B Inhibitors …
Matched Products: … RASAGILIN BETA 1 MG ... RASAGILINA DOC GENERICI …
Dexpropranolol
Experimental
Matched Synonyms: … D-Propranolol …
Matched Categories: … Adrenergic beta-Antagonists …
Matched Categories: … Adrenergic beta-Antagonists …
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mirvetuximab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Cinrebafusp alfa
Investigational
Matched Synonyms: … ) (HUMAN-MUS MUSCULUS MONOCLONAL PRS-343 .GAMMA.4-CHAIN) FUSION PROTEIN PEPTIDE (SYNTHETIC 15-AMINO ACID …
Displaying drugs 3601 - 3625 of 3952 in total