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Displaying drugs 3651 - 3675 of 4292 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Victoria/2570/2019 IVR-215 (H1N1) antigen (propiolactone inactivated) …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … identify and destroy the virus. ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Victoria/4897/2022 IVR-238 (H1N1) Antigen (propiolactone inactivated) …
Matched Description: … identify and destroy the virus. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A Virus A/California/122/2022 SAN-022 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … identify and destroy the virus. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring. It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Initially introduced in 1983...
Experimental
Matched Synonyms: … 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine …
Matched Description: … It is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative ... Initially introduced in 1983 in Japan as treatment for neurological conditions such as anxiety and sleep ... and skeletal muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
Investigational
Matched Synonyms: … Antineoplaston A 10 …
Matched Name: … Antineoplaston A10
Matched Description: … Liver Cancer, and Kidney Cancer, among others. ... Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, …
Approved
Matched Synonyms: … L-DPPG-Na …
Investigational
Matched Synonyms: … Recombinant human highly phosphorylated alpha-L-iduronidase …
Midecamycin is a naturally occurring 16-membered macrolide that fits under the category of acetoxy-substituted macrolide antibiotics. In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position 4 of the terminal sugar. Until 2017, midecamycin was still under the list of approved...
Experimental
Matched Synonyms: … Espinomycin A ... Medemycin A1 ... Medecamycin A1
Matched Description: … In this molecule, an acetoxy group is substituted on the position 9 of the 16-member ring and on position ... Midecamycin is a naturally occurring 16-membered macrolide[A33072] that fits under the category of acetoxy-substituted …
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … in a pH-dependent manner ... GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Experimental
Matched Name: … 1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid
Matched Iupac: … 4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Iupac: … (acetylsulfanyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydrospiro[cyclopenta[a] …
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ALDACTONE A ... SPIRONOLACTON AL 50 ... SPIRONOLACTON AL 100 …
Experimental
Matched Name: … 5-Thio-a/B-D-Mannopyranosylamine …
RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.
Investigational
Matched Synonyms: … recombinant adeno-associated virus vector encoding human CYP4V2 protein
Matched Description: … RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein. …
Experimental
Matched Name: … 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE …
A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin...
Approved
Investigational
Matched Synonyms: … DILACTONE ACTINOMYCIN D ACID ... ANA-conjugated dactinomycin nanoemulsion ... CARBONYLIMINOISOBUTYLIDENECARBONYL-1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE …
Matched Description: … It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than ... As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. ... A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances ... Nucleic Acid Synthesis Inhibitors ... Protein Synthesis Inhibitors …
Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Iupac: … 1-(2-methylphenyl)-4-(2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}ethyl)piperazine …
Matched Description: … Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. ... It is found in ophthalmic solutions used to reverse mydriasis after an eye examination. …
Matched Salts name: … Dapiprazole hydrochloride
Matched Categories: … Antiglaucoma Preparations and Miotics …
Experimental
Matched Synonyms: … Endo-1,4-beta-xylanase A
Matched Categories: … Enzymes and Coenzymes
Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor. Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).
Investigational
Matched Synonyms: … 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A) ... 6-[(3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3- tetrahydropyran-4-yl-7H-imidazo[1,5-a] ... 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin …
Matched Iupac: … 6-[(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl]-3-(oxan-4-yl)-7H,8H-imidazo[1,5-a]pyrazin …
Matched Description: … Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor ... Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With …
A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Synonyms: … Interleukin-2/diptheria toxin fusion protein
Matched Description: … A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin ... fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133 ... It is produced in an E. coli expression system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Intercellular Signaling Peptides and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins
Approved
Matched Synonyms: … Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b nhba fusion protein antigen …
Approved
Matched Synonyms: … Neisseria meningitidis serogroup B recombinant NADA fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b nada protein antigen …
Investigational
Matched Synonyms: … Protein cardiotrophin (human isoform 1) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Description: … exists as a racemic mixture of the active S(-) and R(+) forms. ... and toxicities. ... [A714, A228543] Thalidomide and its analogues, including lenalidomide, are referred to as immunomodulatory …
Matched Salts name: … Lenalidomide hydrochloride monohydrate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Acids, Carbocyclic ... Carboxylic Acids ... Phthalic Acids ... Drugs that are Mainly Renally Excreted …
Matched Products: … LENALIDOMIDE ACINO ... Apo-lenalidomide …
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY .GAMMA.4 HEAVY CHAIN ... IMMUNOGLOBULIN G4 (226-PROLINE), ANTI-(HUMAN MANNAN-BINDING LECTIN-ASSOCIATED SERINE PROTEASE 2) (HUMAN ... IMMUNOGLOBULIN G4-LAMBDA, ANTI-(HOMO SAPIENS MANNAN-BINDING LECTIN SERINE PROTEASE 2 (MANNOSE-BINDING …
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and IgA nephropathy ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Displaying drugs 3651 - 3675 of 4292 in total