Displaying drugs 3826 - 3850 of 9781 in total
AZD 3355
AZD 3355 is a reflux inhibitor used for the treatment of Gastroesophageal Reflux Disease. It is developed by AstraZeneca and is currently in phase I/II trials.
Investigational
Matched Description: … It is developed by AstraZeneca and is currently in phase I/II trials. …
LSZ-102
LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
Investigational
Matched Iupac: … (2E)-3-[4-({2-[2-(1,1-difluoroethyl)-4-fluorophenyl]-6-hydroxy-1-benzothiophen-3-yl}oxy)phenyl]prop-2 …
Matched Description: … LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
3-Indolebutyric Acid
Experimental
Matched Name: … 3-Indolebutyric Acid …
Matched Iupac: … 4-(1H-indol-3-yl)butanoic acid …
Matched Iupac: … 4-(1H-indol-3-yl)butanoic acid …
3-Iodo-Benzyl Alcohol
Experimental
Matched Name: … 3-Iodo-Benzyl Alcohol …
Matched Iupac: … (3-iodophenyl)methanol …
Matched Iupac: … (3-iodophenyl)methanol …
Itepekimab
Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Gondoic acid
Experimental
Tenalisib
Tenalisib is under investigation in clinical trial NCT03711604 (Compassionate Use Study of Tenalisib (RP6530)).
Investigational
Matched Synonyms: … 3-(3-FLUOROPHENYL)-2-((1S)-1-((7H-PURIN-6-YL)AMINO)PROPYL)-4H-1-BENZOPYRAN-4-ONE ... 4H-1-BENZOPYRAN-4-ONE, 3-(3-FLUOROPHENYL)-2-((1S)-1-(9H-PURIN-6-YLAMINO)PROPYL)- ... (S)-2-(1-(9H-Purin-6-Ylamino)Propyl)-3-(3-Fluorophenyl)-4H-Chromen-4-One) …
Matched Iupac: … 3-(3-fluorophenyl)-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphoinositide-3 Kinase Inhibitors …
Matched Iupac: … 3-(3-fluorophenyl)-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphoinositide-3 Kinase Inhibitors …
CC-90001
Investigational
Matched Synonyms: … 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE ... 2-((1,1-DIMETHYLETHYL)AMINO)-4-(((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYL)AMINO)-5-PYRIMIDINECARBOXAMIDE ... 5-PYRIMIDINECARBOXAMIDE, 2-((1,1-DIMETHYLETHYL)AMINO)-4-(((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYL)AMINO …
Matched Iupac: … 2-(tert-butylamino)-4-{[(1R,3R,4R)-3-hydroxy-4-methylcyclohexyl]amino}pyrimidine-5-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-(tert-butylamino)-4-{[(1R,3R,4R)-3-hydroxy-4-methylcyclohexyl]amino}pyrimidine-5-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
3-(5-Amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid
3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid is a solid. This compound belongs to the aminobenzoic acid derivatives. These are benzoic acids (or derivatives thereof) containing an amine group attached to the benzene moiety. 3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid targets the protein methionine aminopeptidase.
Experimental
Matched Name: … 3-(5-Amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid …
Matched Iupac: … 3-[2-(3,5-diimino-4,5-dihydro-3H-pyrazol-4-ylidene)hydrazin-1-yl]benzoic acid …
Matched Description: … 3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid is a solid. ... (5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid targets the protein methionine aminopeptidase. ... are benzoic acids (or derivatives thereof) containing an amine group attached to the benzene moiety. 3- …
Matched Iupac: … 3-[2-(3,5-diimino-4,5-dihydro-3H-pyrazol-4-ylidene)hydrazin-1-yl]benzoic acid …
Matched Description: … 3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid is a solid. ... (5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid targets the protein methionine aminopeptidase. ... are benzoic acids (or derivatives thereof) containing an amine group attached to the benzene moiety. 3- …
Rodatristat
Investigational
Matched Synonyms: … 2,8-diazaspiro(4.5)decane-3-carboxylic acid, 8-(2-amino-6-((1r)-1-(5-chloro(1,1'-biphenyl)-2-yl)-2,2,2 ... (4.5)decane-3-carboxylic acid ... (4.5)decane-3-carboxylic acid …
Matched Iupac: … [4.5]decane-3-carboxylic acid ... (3S)-8-{2-amino-6-[(1R)-1-{5-chloro-[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … [4.5]decane-3-carboxylic acid ... (3S)-8-{2-amino-6-[(1R)-1-{5-chloro-[1,1'-biphenyl]-2-yl}-2,2,2-trifluoroethoxy]pyrimidin-4-yl}-2,8-diazaspiro …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Muplestim
Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia).
Investigational
Matched Synonyms: … Interleukin 3 ... Interleukin-3 ... Interleukin 3 (human) …
Matched Description: … the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3 ... Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate …
Matched Categories: … Interleukin-3 …
Matched Description: … the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3 ... Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate …
Matched Categories: … Interleukin-3 …
(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE
Experimental
Matched Name: … (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE …
Matched Iupac: … (1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate …
Matched Iupac: … (1R,3R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate …
Hydroquinidine
Hydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).
Investigational
Matched Iupac: … (S)-[(1S,2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Categories: … Antiarrhythmics, Class I …
Matched Categories: … Antiarrhythmics, Class I …
Etynodiol
Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see DB00823), not etynodiol.
Experimental
Etavopivat
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … -c)pyrrol-2(1h)-yl)-3-hydroxy-2-phenyl-, (2s)- ... 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 …
Matched Iupac: … -3-hydroxy-2-phenylpropan-1-one ... (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …
Matched Iupac: … -3-hydroxy-2-phenylpropan-1-one ... (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …
2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol
Experimental
Matched Synonyms: … 1,4:3,6-Dianhydro-2,5-bis-O-(3-carbamimidoylphenyl)-D-glucitol …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
Matched Name: … 2,5-bis-O-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-D-glucitol …
Matched Iupac: … 3-{[(3R,3aR,6S,6aR)-6-(3-carbamimidoylphenoxy)-hexahydrofuro[3,2-b]furan-3-yl]oxy}benzene-1-carboximidamide …
LJP 1082
LJP 1082 is a Toleragen that is designed to shut down the B cells that produce antibodies to ß2 GP1. LJP 1082 is undergoing trial for for the treatment of stroke, deep-vein thrombosis and other conditions associated with antibody-mediated thrombosis. Antibody-mediated thrombosis, also called antiphospholipid syndrome (APS), is a blood...
Investigational
Matched Iupac: … 2-amino-4-({1-[(carboxymethyl)carbamoyl]-2-[(hydroxymethyl)sulfanyl]ethyl}carbamoyl)butanoic acid …
Matched Description: … 1082's clot-promoting antibodies is a small region on a key blood protein called beta 2-glycoprotein I. …
Matched Description: … 1082's clot-promoting antibodies is a small region on a key blood protein called beta 2-glycoprotein I. …
(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL
Experimental
Matched Name: … (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL …
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-8-[(1Z)-but-1-en-1-yl]-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta …
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-8-[(1Z)-but-1-en-1-yl]-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta …
L-377202
L-377202 is under investigation in clinical trial NCT00987753 (Study Evaluating the Safety and Tolerability of L-377202).
Investigational
Matched Synonyms: … 5,12-NAPHTHACENEDIONE, 10-((3-(((4R)-1-(4-CARBOXY-1-OXOBUTYL)-4-HYDROXY-L-PROLYL-L-ALANYL-L-SERYL-(2S ... ,4s,6r)-3-hydroxy-2-methyl-6-(((1s,3s)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4 ... 5-((2s,4r)-2-(((1s)-2-(((1s)-2-(((1s)-2-(((1s)-4-amino-1-(((1s)-1-(hydroxymethyl)-2-(((1s)-1-(((2s,3s …
ASC-JM-17
Investigational
(S)-DES-ME-AMPA
Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-isoxazol-4-yl)propionic acid …
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid …
3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one
Experimental
Matched Name: … 3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2(1H)-one …
Matched Iupac: … 3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-3-yl]-4H-1lambda6,2,4-benzothiadiazine-1,1-dione …
Matched Iupac: … 3-[4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-3-yl]-4H-1lambda6,2,4-benzothiadiazine-1,1-dione …
Quabodepistat
Investigational
Matched Synonyms: … 2(1H)-QUINOLINONE, 5-(((3R,4R)-1-(4-CHLORO-2,6-DIFLUOROPHENYL)-3,4-DIHYDROXY-4-PIPERIDINYL)METHOXY)-8 ... 5-(((3r,4r)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl)methoxy)-8-fluoro-3,4-dihydroquinolin ... 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-3,4-dihydroquinolin …
Matched Iupac: … 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-1,2,3,4-tetrahydroquinolin …
Matched Iupac: … 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-1,2,3,4-tetrahydroquinolin …
Displaying drugs 3826 - 3850 of 9781 in total