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Displaying drugs 3851 - 3875 of 8310 in total
4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one
Experimental
Matched Name: … 4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one …
Matched Iupac: … 4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one …
Matched Iupac: … 4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one …
2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE
Experimental
Matched Name: … 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE …
Matched Iupac: … 2-(ethoxymethyl)-4-(4-fluorophenyl)-3-[2-(2-hydroxyphenoxy)pyrimidin-4-yl]-2,5-dihydro-1,2-oxazol-5-one …
Matched Iupac: … 2-(ethoxymethyl)-4-(4-fluorophenyl)-3-[2-(2-hydroxyphenoxy)pyrimidin-4-yl]-2,5-dihydro-1,2-oxazol-5-one …
dATP
Experimental
Matched Synonyms: … 2'-Deoxyadenosine 5'-triphosphate ... Deoxyadenosine 5'-triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
INO-1001
Investigational
Matched Synonyms: … (9-(N-(3-Morpholinopropyl)-sulfonyl)-5,6-dihydro-5-oxo-11-H-indeno (1,2-C) isoquinoline methanesulfonic …
Matched Iupac: … N-[3-(morpholin-4-yl)propyl]-5-oxo-5H,6H,11H-indeno[1,2-c]isoquinoline-9-sulfonamide; methanesulfonic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-[3-(morpholin-4-yl)propyl]-5-oxo-5H,6H,11H-indeno[1,2-c]isoquinoline-9-sulfonamide; methanesulfonic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
SP2456
Experimental
Matched Synonyms: … (2R)-2-Cyclohexyl-2-(diaminomethylideneamino)-N-[2-[4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin ... -1-yl]-2-oxoethyl]acetamide …
Matched Iupac: … (2R)-2-cyclohexyl-2-[(diaminomethylidene)amino]-N-(2-{4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin ... -1-yl}-2-oxoethyl)acetamide …
Matched Iupac: … (2R)-2-cyclohexyl-2-[(diaminomethylidene)amino]-N-(2-{4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin ... -1-yl}-2-oxoethyl)acetamide …
Citrulline
Citrulline is an amino acid. It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. Its name is derived from citrullus, the Latin word for watermelon,...
Investigational
Nutraceutical
Matched Synonyms: … 2-Amino-5-ureidovaleric acid ... (S)-2-Amino-5-ureidopentanoic acid ... L-2-Amino-5-ureidovaleric acid …
Matched Iupac: … (2S)-2-amino-5-(carbamoylamino)pentanoic acid …
Matched Salts cas: … 70796-17-7 …
Matched Iupac: … (2S)-2-amino-5-(carbamoylamino)pentanoic acid …
Matched Salts cas: … 70796-17-7 …
Zilebesiran
Zilebesiran is under investigation in clinical trial NCT06272487 (Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3)).
Investigational
Matched Synonyms: … (2S,4R)-1-{1-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-16,16-bis({3-[(3-{5-[(2- acetamido-2-deoxy-β-D-galactopyranosyl …
ABX-002
Investigational
Matched Synonyms: … 2-(3,5-DICHLORO-4-((4-HYDROXY-3-(PROPAN-2-YL)PHENYL)METHYL)PHENOXY)-N-METHYLACETAMIDE …
Matched Iupac: … 2-(3,5-dichloro-4-{[4-hydroxy-3-(propan-2-yl)phenyl]methyl}phenoxy)-N-methylacetamide …
Matched Iupac: … 2-(3,5-dichloro-4-{[4-hydroxy-3-(propan-2-yl)phenyl]methyl}phenoxy)-N-methylacetamide …
N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide
Experimental
Matched Synonyms: … 2-[2-Chloro-5-(trifluoromethyl)phenyl]-1-(diaminomethylene)guanidine …
Matched Name: … N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
Matched Name: … N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
(2s)-2-[(5-Benzofuran-2-Yl-Thiophen-2-Ylmethyl)-(2,4-Dichloro-Benzoyl)-Amino]-3-Phenyl-Propionic Acid
Experimental
Matched Name: … (2s)-2-[(5-Benzofuran-2-Yl-Thiophen-2-Ylmethyl)-(2,4-Dichloro-Benzoyl)-Amino]-3-Phenyl-Propionic Acid …
Matched Iupac: … (2S)-2-(N-{[5-(1-benzofuran-2-yl)thiophen-2-yl]methyl}-1-(2,4-dichlorophenyl)formamido)-3-phenylpropanoic …
Matched Iupac: … (2S)-2-(N-{[5-(1-benzofuran-2-yl)thiophen-2-yl]methyl}-1-(2,4-dichlorophenyl)formamido)-3-phenylpropanoic …
Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Experimental
Matched Name: … Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate …
Matched Iupac: … benzyl N-[(1S)-4-[(diaminomethyl)amino]-1-{[(2S)-4-fluoro-3-oxobutan-2-yl]carbamoyl}butyl]carbamate …
Matched Iupac: … benzyl N-[(1S)-4-[(diaminomethyl)amino]-1-{[(2S)-4-fluoro-3-oxobutan-2-yl]carbamoyl}butyl]carbamate …
Plumbagin
Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.
Investigational
Matched Synonyms: … 5-hydroxy-2-methyl-1,4-naphthalenedione …
Matched Iupac: … 5-hydroxy-2-methyl-1,4-dihydronaphthalene-1,4-dione …
Matched Iupac: … 5-hydroxy-2-methyl-1,4-dihydronaphthalene-1,4-dione …
Plinabulin
Investigational
Matched Iupac: … (3Z,6Z)-3-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]-6-(phenylmethylidene)piperazine-2,5-dione …
1-[(4S)-4-amino-5-(1,3-benzothiazol-2-yl)-5-oxopentyl]guanidine
Experimental
Matched Name: … 1-[(4S)-4-amino-5-(1,3-benzothiazol-2-yl)-5-oxopentyl]guanidine …
Matched Iupac: … N-[(4S)-4-amino-5-(1,3-benzothiazol-2-yl)-5-oxopentyl]guanidine …
Matched Iupac: … N-[(4S)-4-amino-5-(1,3-benzothiazol-2-yl)-5-oxopentyl]guanidine …
Quabodepistat
Investigational
Matched Synonyms: … 2(1H)-QUINOLINONE, 5-(((3R,4R)-1-(4-CHLORO-2,6-DIFLUOROPHENYL)-3,4-DIHYDROXY-4-PIPERIDINYL)METHOXY)-8 ... -2(1h)-one ... -2(1H)-one …
Matched Iupac: … -2-one ... 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-1,2,3,4-tetrahydroquinolin …
Matched Iupac: … -2-one ... 5-{[(3R,4R)-1-(4-chloro-2,6-difluorophenyl)-3,4-dihydroxypiperidin-4-yl]methoxy}-8-fluoro-1,2,3,4-tetrahydroquinolin …
(4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone
Experimental
Matched Synonyms: … (4S)-5-Fluoro-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one …
Matched Name: … (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone …
Matched Iupac: … (4S)-5-fluoro-4-hydroxy-1,2,3,4-tetrahydropyrimidin-2-one …
Matched Name: … (4S)-5-Fluoro-4-hydroxy-3,4-dihydro-2(1H)-pyrimidinone …
Matched Iupac: … (4S)-5-fluoro-4-hydroxy-1,2,3,4-tetrahydropyrimidin-2-one …
Coprogen
Experimental
Matched Iupac: … -2-yl]propyl}(oxido)carbamoyl)-3-methylbut-3-en-1-yl (2S)-2-acetamido-5-[(2E)-5-hydroxy-3-methyl-N-oxidopent ... iron(3+) (3E)-4-({3-[(2S,5S)-5-{3-[(2E)-5-hydroxy-3-methyl-N-oxidopent-2-enamido]propyl}-3,6-dioxopiperazin ... -2-enamido]pentanoate …
Incadronic acid
Incadronate, or YM-175, is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy, it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427,A202769]
Incadronic acid was first described in the literature in 1991.
Experimental
NP-51
Investigational
Matched Synonyms: … (+/-)-o-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime ... 3-pyridinecarboximidamide, n-(2-hydroxy-3-(1-piperidinyl)propoxy)- …
Matched Iupac: … N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide …
Matched Iupac: … N-[2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide …
Suramin
A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties. Suramin...
Investigational
Matched Iupac: … 8-{4-methyl-3-[3-({[3-({2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)phenyl] …
Sparteine
Sparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents. Sparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one...
Experimental
Withdrawn
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tasadenoturev
Investigational
Matched Synonyms: … Tumor-selective delta-24 ,rgd modified adenovirus serotype 5 …
(3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,7(8H)-DIONE
Experimental
Matched Name: … (3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE …
Matched Iupac: … (3R,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,7,8,9,10-hexahydro-1H-2-benzoxacyclotetradecine …
Matched Iupac: … (3R,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,7,8,9,10-hexahydro-1H-2-benzoxacyclotetradecine …
WU-CART-007
WU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Investigational
(S)-famoxadone
Experimental
Matched Synonyms: … (S)-5-Methyl-5-(4-phenoxy-phenyl)-3-phenylamino-oxazolidine-2,4-dione …
Matched Iupac: … (5S)-5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione …
Matched Iupac: … (5S)-5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione …
Displaying drugs 3851 - 3875 of 8310 in total