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Displaying drugs 3876 - 3900 of 9975 in total
Ukrain cation
Investigational
Matched Iupac: … (1S,12S,13R)-24-(2-{[bis({2-[(1S,12S,13R)-12-hydroxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0 …
NSI-189
NSI-189 is under investigation in clinical trial NCT02695472 (Study of NSI-189 for Major Depressive Disorder).
Investigational
Matched Iupac: … 3-(4-benzylpiperazine-1-carbonyl)-N-(3-methylbutyl)pyridin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dimefline
Experimental
Matched Iupac: … 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
Experimental
Matched Name: … 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE …
Matched Iupac: … 2-[2-(quinolin-3-yl)pyridin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one …
Matched Iupac: … 2-[2-(quinolin-3-yl)pyridin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one …
(2S)-2-(1H-indol-3-yl)pentanoic acid
Experimental
Matched Name: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
Matched Iupac: … (2S)-2-(1H-indol-3-yl)pentanoic acid …
(2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid
Experimental
Matched Name: … (2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene …
Matched Iupac: … (2R)-2-[(1R)-1-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene …
Matched Iupac: … (2R)-2-[(1R)-1-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene …
10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine
Experimental
Matched Iupac: … 15,16-dimethoxy-6-methyl-8,12-diazatetracyclo[8.8.0.0^{2,7}.0^{13,18}]octadeca-1(18),2,4,6,8,10,12,14,16 …
CGS-27023
Experimental
Matched Iupac: … (2R)-N-hydroxy-3-methyl-2-{N-[(pyridin-3-yl)methyl]4-methoxybenzenesulfonamido}butanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ORG-25935
Org 25935 has been used in trials studying the treatment of Alcoholism, Schizophrenia, and Panic Disorder.
Investigational
Matched Iupac: … 2-({[(1R,2S)-6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl]methyl}(methyl)amino)acetic acid …
SB-218078
SB-218078 is a specific inhibitor of CHK1.
Investigational
Matched Synonyms: … 9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3 ... 9,12-epoxy-1h-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-1,3(2h)-dione, 9,10,11,12 …
Matched Iupac: … 26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-3,5-dione ... oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1( …
Matched Iupac: … 26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-3,5-dione ... oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1( …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … (1-445) (HOMO SAPIENS VH (IGHV2-26*01 (94%) (IGHD)-I ... MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 …
Matched Description: … [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as …
Matched Description: … [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as …
Eltanolone
Eltanolone is under investigation in clinical trial NCT02603926 (Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone).
Investigational
Matched Iupac: … ]ethan-1-one ... 1-[(1S,2S,5R,7R,10R,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl …
Sepranolone
Sepranolone has been investigated for the treatment of Premenstrual Dysphoric Disorder.
Investigational
Matched Iupac: … 1-[(1S,3aS,3bR,5aS,7S,9aS,9bS,11aS)-7-hydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren ... -1-yl]ethan-1-one …
VX-702
VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor. In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Investigational
Matched Iupac: … 2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide …
VX-765
VX-765 is the orally available prodrug of a potent and selective competitive inhibitor of ICE/caspase-1 (VRT-043198). VX-765 is currently under clinical development for the treatment of inflammatory and autoimmune conditions, as it blocks the hypersensitive response to an inflammatory stimulus.
Investigational
Matched Description: … -765 is the orally available prodrug of a potent and selective competitive inhibitor of ICE/caspase-1 …
PG-701
Hydroxytriptolide has been investigated for the treatment of Rheumatoid Arthritis.
Investigational
Matched Iupac: … (1S,2S,4S,5S,7R,8R,9S,11S,13R)-8,13-dihydroxy-1-methyl-7-(propan-2-yl)-3,6,10,16-tetraoxaheptacyclo[11.7.0.0 …
E-7820
E7820 has been investigated for the treatment of Colon Cancer and Rectal Cancer.
Investigational
Matched Iupac: … 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
OT-730
OT-730 is under investigation in clinical trial NCT00753168 (Phase 1-2 Evaluation of OT-730 Eye Drops in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucoma).
Investigational
Matched Iupac: … (2S)-3-({2-methyl-1-[(oxolan-3-yl)formamido]propan-2-yl}amino)-2-(1-methylcyclopropanecarbonyloxy)propyl ... 4,5-dihydroxy-2-methylbenzoate …
Matched Description: … OT-730 is under investigation in clinical trial NCT00753168 (Phase 1-2 Evaluation of OT-730 Eye Drops …
Matched Description: … OT-730 is under investigation in clinical trial NCT00753168 (Phase 1-2 Evaluation of OT-730 Eye Drops …
LH-708
Investigational
Matched Synonyms: … 1-propanone, 3,3'-dithiobis(2-amino-1-(4-methyl-1-piperazinyl)-, (2r,2'r)- …
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-3-(4-methylpiperazin-1-yl)-3-oxopropyl]disulfanyl}-1-(4-methylpiperazin ... -1-yl)propan-1-one …
Matched Iupac: … (2R)-2-amino-3-{[(2R)-2-amino-3-(4-methylpiperazin-1-yl)-3-oxopropyl]disulfanyl}-1-(4-methylpiperazin ... -1-yl)propan-1-one …
N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE
Experimental
Matched Name: … N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE …
Matched Iupac: … 9,10,11,12-tetrabromo-5-methyl-2,5,7-triazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),6,8,10-tetraene …
Matched Iupac: … 9,10,11,12-tetrabromo-5-methyl-2,5,7-triazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),6,8,10-tetraene …
Octyl triazone
Experimental
Matched Iupac: … 2-ethylhexyl 4-({4,6-bis[(4-{[(2-ethylhexyl)oxy]carbonyl}phenyl)amino]-1,3,5-triazin-2-yl}amino)benzoate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
[(3R,4S,5S,7R)-4,8-DIHYDROXY-3,5,7-TRIMETHYL-2-OXOOCTYL]PHOSPHONIC ACID
Experimental
Matched Name: … [(3R,4S,5S,7R)-4,8-DIHYDROXY-3,5,7-TRIMETHYL-2-OXOOCTYL]PHOSPHONIC ACID …
Matched Iupac: … [(3R,4S,5S,7R)-4,8-dihydroxy-3,5,7-trimethyl-2-oxooctyl]phosphinic acid …
Matched Iupac: … [(3R,4S,5S,7R)-4,8-dihydroxy-3,5,7-trimethyl-2-oxooctyl]phosphinic acid …
Displaying drugs 3876 - 3900 of 9975 in total