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Displaying drugs 3951 - 3975 of 4281 in total
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Victoria/210/2009 X-187 (H3N2) hemagglutinin antigen (UV, formaldehyde inactivated …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …
Matched Iupac: … )-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy]phosphinic acid
Experimental
Matched Name: … S-[3-(3,4-DICHLOROPHENYL)-3-OXOPROPYL]-L-CYSTEINE …
Matched Iupac: … (2R)-2-amino-3-{[3-(3,4-dichlorophenyl)-3-oxopropyl]sulfanyl}propanoic acid
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Synonyms: … bosentan anhydrous
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and ... Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Sulfur Compounds …
Matched Products: … N/A ... Act Bosentan ... Apo-bosentan …
Experimental
Illicit
Matched Synonyms: … D,L-p-methoxyamphetamine …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Investigational
Matched Synonyms: … methoxycarbonyl)-7-methyl-3-oxo-8-(3-(trifluoromethyl)phenyl)-2,3,5,8-tetrahydro-(1,2,4)triazolo(4,3-a) ... methoxycarbonyl)-7-methyl-3-oxo-8-(3-(trifluoromethyl)phenyl)-2,3,5,8-tetrahydro-(1,2,4)triazolo(4,3-a) ... 2,3,5,8-tetrahydro-6-(methoxycarbonyl)-7-methyl-3-oxo-8-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,3-a) …
Matched Iupac: … 5R)-6-(methoxycarbonyl)-7-methyl-3-oxo-8-[3-(trifluoromethyl)phenyl]-2H,3H,5H,8H-[1,2,4]triazolo[4,3-a] …
Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(candida heat-shock protein hsp 90) (human monoclonal hsp90mab fragment) …
Matched Description: … Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... HSP90 Heat-Shock Proteins
Investigational
Matched Synonyms: … chimeric antigen receptor (CAR) directed against the target protein CD5 …
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein
Matched Description: … vascular adhesion protein-1 (VAP-1). ... Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Approved
Experimental
Matched Synonyms: … Rudbeckia purpurea l. ... Brauneria purpurea (l.) britton ... Echinacea purpurea (l.) moench …
Matched Categories: … Herbs and Natural Products …
As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational
Matched Synonyms: … AP-TP-V ... COVID-19 AP TP Vaccine ... COVID-19 Therapeutic Vaccine - Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection …
Matched Name: … COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection …
Matched Description: … vaccine efficacy through prolongation of humoral and cell immunity. ... As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for ... the COVID-19 AP TP Vaccine for ‘proof of concept.’ …
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Cough and Cold Preparations ... Proteins
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/gp1908/2015 IVR-180 (H1N1) hemagglutinin antigen (MDCK cell derived, propiolactone …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy …
Equus caballus skin allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Equus przewalskii forma caballus skin …
Matched Mixtures name: … Horse Hair and Dander …
Experimental
Matched Synonyms: … PLASMINOGEN ACTIVATOR, PRO- (HUMAN LIVER UROKINASE-TYPE PROTEIN MOIETY REDUCED) ... KINASE (ENZYME-ACTIVATING), PROURO- (HUMAN CLONE PUK4/PUK18 PROTEIN MOIETY REDUCED) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Proteins ... Blood Proteins
Experimental
Matched Name: … Methoxy-(3-((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Oxa-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous ... [L40719] It has a number of therapeutic uses, including the management and prevention of infections and ... G-CSF and has an N-terminal methionine added in the sequence for expression in _E. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins
Matched Products: … ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML ... ACCOFIL 48 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 48 MU/0.5 ML …
Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … See toxicity section below for a complete listing of side effects. ... Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). ... as amitriptyline and clomipramine. …
Matched Salts name: … Desipramine hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Drugs that are Mainly Renally Excreted ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … Desipramine Hydrochloride
AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting, effector function null, humanized IgG1 antibody (AV01mAb) conjugated to one small interfering RNA (siRNA).
Investigational
Matched Synonyms: … an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 (TfR1) targeting …
Matched Name: … AOC 1001 …
Matched Description: … AOC 1001 is an antibody oligonucleotide conjugate (AOC), comprised of a human transferrin receptor 1 …
Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)).
Investigational
Matched Synonyms: … -l-lyxo-hexopyranosyl)oxy)-3'-fluoro(1,1'-biphenyl)-2-yl)ethyl)- …
Matched Description: … Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients …
Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Synonyms: … Recombinant human endostatin protein
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins ... Angiogenic Proteins ... Angiostatic Proteins
OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Investigational
Matched Synonyms: … Humanized immunoglobulin G4 monoclonal antibody directed against mannan-binding lectin-associated serine protease
Matched Description: … OMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease
Experimental
Matched Synonyms: … Sambucus nigra l. flower …
Investigational
Matched Synonyms: … L-NDDP …
Methylene blue is an oxidation-reduction agent. The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia. Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered...
Approved
Investigational
Matched Synonyms: … Methylene blue anhydrous
Matched Description: … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult ... Historically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and ... drug being developed by the University of Aberdeen and TauRx Therapeutics that has been shown in early …
Matched Mixtures name: … Uro-L
Matched Categories: … Sulfur Compounds ... Drugs that are Mainly Renally Excreted …
Matched Products: … Methylene Bleu Liq 1% ... Methylene Bleu Liq 2% …
Displaying drugs 3951 - 3975 of 4281 in total