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Displaying drugs 4001 - 4025 of 4208 in total
ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Synonyms: … ST-101 (D-AMINO ACID PEPTIDE) ... D-valyl-D-alanyl-D-α-glutamyl-D-alanyl-D-arginyl-D-α-glutamyl-D-α-glutamyl-D-leucyl-D-α-glutamyl-D-arginyl-D-leucyl-D-α-glutamyl-D-alanyl-D-arginyl-D-leucylglycyl-D-glutaminyl-D-alanyl-D-arginylglycyl-D-α-glutamyl-D-leucyl-D-lysyl-D-lys
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Experimental
Matched Name: … 1-Deoxy-6-O-Phosphono-1-[(Phosphonomethyl)Amino]-L-Threo-Hexitol …
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-[(phosphonomethyl)amino]hexyl]oxy}phosphonic acid
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. This compound belongs to the n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. It is known to target cathepsin K.
Experimental
Matched Name: … N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide …
Matched Description: … This compound belongs to the n-acyl-alpha amino acids and derivatives. ... These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group ... N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. …
Experimental
Matched Name: … S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE …
Matched Iupac: … (2R)-2-amino-3-[(2-{[4-(phenylamino)quinazolin-6-yl]carbamoyl}ethyl)sulfanyl]propanoic acid
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … carbamoyl}-3-[(2R)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid
Matched Description: … and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant ... [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs that are Mainly Renally Excreted …
Matched Products: … CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...
Approved
Investigational
Matched Description: … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications ... than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. ... safer and more effective alternatives for patients with type 2 diabetes mellitus. …
Matched Mixtures name: … Pioglitazone Hydrochloride and Metformin Hydrochloride ... Pioglitazone Hydrochloride and Metformin Hydrochloride ... Pioglitazone and Metformin Hydrochloride
Matched Salts name: … Pioglitazone hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... metformin and pioglitazone ... pioglitazone and alogliptin ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Matched Products: … PIO - LN 15 ... PIO - LN 30 ... Pioglitazone Hydrochloride
Investigational
Matched Synonyms: … Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human monoclonal bi754091 …
Investigational
Matched Synonyms: … Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Experimental
Matched Name: … (3R)-4-(p-toluenesulfonyl)-1,4-thiazane-3-carboxylicacid-L-phenylalanine ethyl ester …
Experimental
Matched Name: … N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine …
Experimental
Matched Name: … N2-({[(4-Bromophenyl)Methyl]Oxy}Carbonyl)-N1-[(1s)-1-Formylpentyl]-L-Leucinamide …
Experimental
Matched Name: … (3s,8ar)-3-(4-Hydroxybenzyl)Hexahydropyrrolo[1,2-a]Pyrazine-1,4-Dione …
Matched Iupac: … (3S,8aS)-3-[(4-hydroxyphenyl)methyl]-octahydropyrrolo[1,2-a]pyrazine-1,4-dione …
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human ... Immunoglobulin g1, anti-(human respiratory syncytial virus fusion protein)(human monoclonal med18897 …
Matched Description: … membrane fusion step of the viral entry process, and neutralizes several RSV A and B strains. ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants ... [L44146] Nirsevimab was also approved by Health Canada on April 19, 2023 and by the FDA in July 17, 2023 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Proteins ... Blood Proteins ... Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody …
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... amino acid position 125. ... This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Drugs that are Mainly Renally Excreted …
Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Five-flavoured Seed
Matched Description: … It is not an approved drug. ... Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. …
Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(multiple sclerosis-associated retrovirus viral envelope protein) (human-mus …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins ... Recombinant Humanized IgG4 Monoclonal Antibody Against pHERV-W Envelope Protein
Experimental
Matched Name: … 3'-O-N-Octanoyl-a-D-Glucopyranosyl-B-D-Fructofuranoside …
Experimental
Matched Name: … 1,3-DI(N-Propyloxy-A-mannopyranosyl)-carbomyl 5-methyazido-benzene …
Experimental
Matched Name: … 1,3,4-TRIHYDROXY-5-(3-PHENOXYPROPYL)-CYCLOHEXANE-1-CARBOXYLIC A CID …
Matched Iupac: … (1S,3R,4R,5S)-1,3,4-trihydroxy-5-(3-phenoxypropyl)cyclohexane-1-carboxylic acid
Experimental
Matched Name: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Matched Iupac: … N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine …
Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Synonyms: … pathway inhibitor (tfpi, extrinsic pathway inhibitor, epi, lipoprotein-associated coagulation inhibitor, laci
Matched Description: … being developed by Pfizer for the treatment of hemophilia A and hemophilia B. ... Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Onfekafusp alfa is under investigation in clinical trial NCT02938299 (Neoadjuvant L19IL2/L19TNF- Pivotal Study).
Investigational
Matched Synonyms: … protein with human tumor necrosis factor .alpha., trimer ... Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion …
Experimental
Matched Name: … DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE ... 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2- …
Matched Iupac: … 3.2.1]octan-3-yl]oxy}propanamido]propanamido]butanamido]-6-{[(1R)-1-carboxyethyl]carbamoyl}hexanoic acid
Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Description: … [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy ... product was FDA approved in 1986, while the combination product of ipratropium and [albuterol] was approved ... Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Salts name: … Ipratropium bromide anhydrous
Matched Categories: … fenoterol and ipratropium bromide ... salbutamol and ipratropium bromide ... Aza Compounds …
Matched Products: … Novo-ipramide - Liq 0.25mg/ml ... Aa-ipravent ... A-TROFINSA …
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Iupac: … phenanthren-1-yl]-2-oxoethoxy}-4-oxobutanoic acid ... )-1,10-dihydroxy-5,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Compounds used in a research, industrial, or household setting …
Matched Products: … A-methapred …
Displaying drugs 4001 - 4025 of 4208 in total