Displaying drugs 4001 - 4025 of 9631 in total
Lirentelimab
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … HEAVY CHAIN (1-450) (VH (HOMO SAPIENS IGHV3-66*01 (79%) (IGHD)-IGHJ5*01 (91%)/MUS ... LECTIN 8 (SIALOADHESIN FAMILY MEMBER 2, SIGLEC-8, SAF-2))HUMANIZED MOUSE MONOCLONAL ANTIBODY.GAMMA.1 ... G1, ANTI-(HUMAN SIALIC ACID-BINDINGE IG-LIKE LECTIN 8) (HUMAN-MUS MUSCULUS MONOCLONAL AK002 .GAMMA.1- …
PIK3CA
PIK3CA is under investigation in clinical trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy).
Investigational
Matched Synonyms: … Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform …
Pegvorhyaluronidase alfa
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … .-(3-CARBOXYPROPYL)-.OMEGA.-METHOXY-, AMIDE WITH HYALURONOGLUCOSAMINIDASE (HUMAN ISOENZYME PH20) ... -(36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ... HUMAN HYALURONIDASE PH-20 (HYALURONOGLUCOSAMINIDASE PH-20, SPERM ADHESION MOLECULE 1, EC 3.2.1.35) PRECURSOR …
6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine
Experimental
Matched Name: … 6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine …
Matched Iupac: … 6-carbamimidoyl-N-[(1S)-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]naphthalene-2-carboxamide …
Matched Iupac: … 6-carbamimidoyl-N-[(1S)-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]naphthalene-2-carboxamide …
3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL
Experimental
Matched Name: … 3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL …
Matched Iupac: … 3-({4-amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl}methyl)phenol …
Matched Iupac: … 3-({4-amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl}methyl)phenol …
3-(1H-tetrazol-5-ylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
Experimental
Matched Name: … 3-(1H-tetrazol-5-ylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one …
Matched Iupac: … -3-one ... 4-[(1H-1,2,3,4-tetrazol-5-yl)methyl]-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien …
Matched Iupac: … -3-one ... 4-[(1H-1,2,3,4-tetrazol-5-yl)methyl]-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien …
Acoramidis
Investigational
Matched Synonyms: … 3-(3-(3,5-dimethyl-1h-pyrazol-4-yl)propoxy)-4-fluorobenzoic acid …
Matched Iupac: … 3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Profadol
Investigational
Matched Synonyms: … Phenol, 3-(1-methyl-3-propyl-3-pyrrolidinyl)- ... M-(1-methyl-3-propyl-3-pyrrolidinyl)phenol ... Phenol, m-(1-methyl-3-propyl-3-pyrrolidinyl)- …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-(1-methyl-3-propylpyrrolidin-3-yl)phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Goflikicept
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 …
Onvansertib
Onvansertib is under investigation in clinical trial NCT03303339 (Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML).).
Investigational
Matched Synonyms: … [4,3-h]quinazoline-3-carboxamide ... 1-(2-Hydroxyethyl)-8-((5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl)amino)-4,5-dihydro-1H-pyrazolo …
Matched Iupac: … [4,3-h]quinazoline-3-carboxamide ... 1-(2-hydroxyethyl)-8-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}-1H,4H,5H-pyrazolo …
Matched Salts cas: … 1263293-37-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … [4,3-h]quinazoline-3-carboxamide ... 1-(2-hydroxyethyl)-8-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}-1H,4H,5H-pyrazolo …
Matched Salts cas: … 1263293-37-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Nisevokitug
Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Description: … transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/ …
Dexpropranolol
Experimental
Matched Synonyms: … (+)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol …
Matched Iupac: … (2R)-1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Iupac: … (2R)-1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE
Experimental
Matched Name: … N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE …
Matched Iupac: … N-methyl-N-[(1S,4r)-4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl]acetamide …
Matched Iupac: … N-methyl-N-[(1S,4r)-4-[(2S,3S)-3-amino-4-[(3S)-3-fluoropyrrolidin-1-yl]-4-oxobutan-2-yl]cyclohexyl]acetamide …
Lorukafusp alfa
Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma).
Investigational
6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole
Investigational
Vonlerolizumab
Vonlerolizumab is under investigation in clinical trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-based Therapy).
Investigational
Matched Synonyms: … heavy chain (1-447) (humanized mouse vh (homo sapiens ighv1-46*01 (81%) ... member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody: .gamma.1 …
Iratumumab
Immunoglobulin G1, anti-(human CD30 (antigen)) (human monoclonal MDX-060 heavy chain), disulfide with human monoclonal MDX-060 light chain, dimer. Molecular weight is approximately 170,000 daltons. In phase I/II clinical trials for treatment of CD30+ lymphomas.
Investigational
Matched Description: … In phase I/II clinical trials for treatment of CD30+ lymphomas. …
Snubh-nm-333 F-18
Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)).
Investigational
Matched Iupac: … 4-[6-(¹⁸F)fluoro-1,3-benzothiazol-2-yl]-N-methylaniline …
Matched Description: … Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical …
Matched Description: … Snubh-nm-333 F-18 is under investigation in clinical trial NCT02149017 (Phase 1 and Phase 2 Clinical …
AAV1-FS344
AAV1-FS344 is an investigational gene therapy developed by Milo Biotechnology to deliver follistatin, a potent myostatin inhibitor. It is being investigated for the treatment of Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and inclusion body myositis.[L46742, L46747, L46752]
Investigational
(1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose
Experimental
Matched Synonyms: … 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYDROXY-7-(SEC-BUTYL)-ANTHRACENE …
Matched Name: … (1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose …
Matched Iupac: … (3R)-7-[(2R)-butan-2-yl]-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-8,9-dihydroxy-1,2,3,4-tetrahydroanthracen ... -1-one …
Matched Name: … (1S)-1-C-{(2R)-6-[(2R)-2-Butanyl]-5,10-dihydroxy-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl}-5-deoxy-1-O-methyl-D-xylulose …
Matched Iupac: … (3R)-7-[(2R)-butan-2-yl]-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-8,9-dihydroxy-1,2,3,4-tetrahydroanthracen ... -1-one …
AGT-182
AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.
Investigational
QXL138AM
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Trazpiroben
Investigational
Matched Synonyms: … (3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8 triazaspiro(4.5) decan-3-yl)methyl)benzoic acid ... Benzoic acid, 3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro(4.5)dec-3-yl)methyl)- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 4001 - 4025 of 9631 in total