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Displaying drugs 4226 - 4250 of 10288 in total
1D-myo-inositol 1,3,4-trisphosphate
Experimental
Onvansertib
Onvansertib is under investigation in clinical trial NCT03303339 (Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML).).
Investigational
Matched Synonyms: … [4,3-h]quinazoline-3-carboxamide ... 1-(2-Hydroxyethyl)-8-((5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl)amino)-4,5-dihydro-1H-pyrazolo …
Matched Iupac: … [4,3-h]quinazoline-3-carboxamide ... 1-(2-hydroxyethyl)-8-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}-1H,4H,5H-pyrazolo …
Matched Salts cas: … 1263293-37-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … [4,3-h]quinazoline-3-carboxamide ... 1-(2-hydroxyethyl)-8-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}-1H,4H,5H-pyrazolo …
Matched Salts cas: … 1263293-37-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
N-[2-Hydroxy-2-(8-Isopropyl-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-11-Yl)-Ethyl]-N-(3-Methyl-Butyl)-Benzenesulfonamide,Inhibitor 3
Experimental
Matched Name: … -11-Yl)-Ethyl]-N-(3-Methyl-Butyl)-Benzenesulfonamide,Inhibitor 3 ... N-[2-Hydroxy-2-(8-Isopropyl-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien …
Matched Iupac: … -11-yl]-2-hydroxyethyl]-N-(3-methylbutyl)benzenesulfonamide ... N-[(2R)-2-[(8S,11S)-6,9-dioxo-8-(propan-2-yl)-2-oxa-7,10-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien …
Matched Iupac: … -11-yl]-2-hydroxyethyl]-N-(3-methylbutyl)benzenesulfonamide ... N-[(2R)-2-[(8S,11S)-6,9-dioxo-8-(propan-2-yl)-2-oxa-7,10-diazabicyclo[11.2.2]heptadeca-1(15),13,16-trien …
2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
Experimental
Matched Name: … 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Matched Iupac: … 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Matched Iupac: … 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Coronavirus-Like Particle COVID-19 Vaccine
The Coronavirus-Like Particle COVID-19 Vaccine is in development and testing through Meidcago in Quebec City, Canada. The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure of the virus without carrying the genetic components required for infection. VLPs are thought to have multiple mechanisms involving the...
Investigational
Matched Description: … of this vaccine candidate with or without either Cpg 1018 or AS03 (NCT04450004) in adults aged 18-55 ... A Phase 1 clinical trial was launched in July 2020 evaluating the safety, tolerability, and immunogenicity …
2-Methyl-3-(2-Aminothiazolo)Propanal
Experimental
Matched Name: … 2-Methyl-3-(2-Aminothiazolo)Propanal …
Matched Iupac: … (2S)-3-(2-amino-1,3-thiazol-4-yl)-2-methylpropanal …
Matched Iupac: … (2S)-3-(2-amino-1,3-thiazol-4-yl)-2-methylpropanal …
4-METHYL-PENTANOIC ACID {1-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYLCARBAMOYL]-2-METHYL-PROPYL}-AMIDE
Experimental
Matched Name: … 4-METHYL-PENTANOIC ACID {1-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYLCARBAMOYL]-2-METHYL-PROPYL}-AMIDE …
Matched Iupac: … N-[(1S)-1-{[(2S)-5-[(diaminomethyl)amino]-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]carbamoyl}-2-methylpropyl …
Matched Iupac: … N-[(1S)-1-{[(2S)-5-[(diaminomethyl)amino]-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]carbamoyl}-2-methylpropyl …
N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE
Experimental
Matched Iupac: … N4-[4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-yl]-N1,N1-dimethylbenzene-1,4-diamine …
4-{(1E)-3-OXO-3-[(2-PHENYLETHYL)AMINO]PROP-1-EN-1-YL}-1,2-PHENYLENE DIACETATE
Experimental
Matched Name: … 4-{(1E)-3-OXO-3-[(2-PHENYLETHYL)AMINO]PROP-1-EN-1-YL}-1,2-PHENYLENE DIACETATE …
Matched Iupac: … 2-(acetyloxy)-5-[(1E)-2-[(2-phenylethyl)carbamoyl]eth-1-en-1-yl]phenyl acetate …
Matched Iupac: … 2-(acetyloxy)-5-[(1E)-2-[(2-phenylethyl)carbamoyl]eth-1-en-1-yl]phenyl acetate …
(3S)-Tetrahydro-3-furanyl {(2S,3S)-4-[(2S,4R)-4-{(1S,2R)-2-[(S)-amino(hydroxy)methoxy]-2,3-dihydro-1H-inden-1-yl}-2-benzyl-3-oxo-2-pyrrolidinyl]-3-hydroxy-1-phenyl-2-butanyl}carbamate
Experimental
Matched Name: … -1-yl}-2-benzyl-3-oxo-2-pyrrolidinyl]-3-hydroxy-1-phenyl-2-butanyl}carbamate ... (3S)-Tetrahydro-3-furanyl {(2S,3S)-4-[(2S,4R)-4-{(1S,2R)-2-[(S)-amino(hydroxy)methoxy]-2,3-dihydro-1H-inden …
Matched Iupac: … benzyl-3-oxopyrrolidin-2-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate ... (3S)-oxolan-3-yl N-{4-[(2S,4R)-4-[(1S,2R)-2-[(S)-amino(hydroxy)methoxy]-2,3-dihydro-1H-inden-1-yl]-2- …
Matched Iupac: … benzyl-3-oxopyrrolidin-2-yl]-3-hydroxy-1-phenylbutan-2-yl}carbamate ... (3S)-oxolan-3-yl N-{4-[(2S,4R)-4-[(1S,2R)-2-[(S)-amino(hydroxy)methoxy]-2,3-dihydro-1H-inden-1-yl]-2- …
Elsubrutinib
Elsubrutinib is under investigation in clinical trial NCT04451772 (A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State).
Investigational
Matched Synonyms: … 1h-indole-7-carboxamide, 4-((3s)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl)- ... (s)-4-(1-acryloylpiperidin-3-yl)-1h-indole-7-carboxamide ... 4-((3s)-1-(prop-2-enoyl)-piperidin-3-yl)-1h-indole-7-carboxamide …
1,2-Di-1-(3,7,11,15-Tetramethyl-Hexadecane)-Sn-Glycero-3-Phosphate
Experimental
Matched Name: … 1,2-Di-1-(3,7,11,15-Tetramethyl-Hexadecane)-Sn-Glycero-3-Phosphate …
3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid
Experimental
Matched Name: … 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid …
Matched Iupac: … 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid …
Matched Iupac: … 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid …
Z-160
Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy.
Investigational
Matched Synonyms: … 1-(4-Benzhydryl-piperazin-1-yl)-3,3-diphenylpropan-1-one ... 1-(4-Benzhydrylpiperazin-1-yl)-3,3-Diphenylpropan-1-one …
Matched Iupac: … 1-[4-(diphenylmethyl)piperazin-1-yl]-3,3-diphenylpropan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[4-(diphenylmethyl)piperazin-1-yl]-3,3-diphenylpropan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Elimusertib
Elimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors).
Investigational
Matched Synonyms: … 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)- …
Ilorasertib
Ilorasertib has been used in trials studying the treatment of Myelodysplasia, Solid Neoplasm, Advanced Cancers, Advanced Solid Tumors, and Acute Myelogenous Leukemia, among others.
Investigational
Matched Synonyms: … 1-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl ... 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridine-3-yl}phenyl)-3-(3-fluorophenyl ... Urea, N-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno(3,2-c)pyridin-3-yl)phenyl)-N'-(3-fluorophenyl …
Matched Iupac: … 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-3-(3-fluorophenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-3-(3-fluorophenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
1-(1-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)PYRROLIDINE-2,5-DIONE
Experimental
Matched Name: … 1-(1-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)PYRROLIDINE-2,5-DIONE …
Matched Iupac: … 1-(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)pyrrolidine-2,5-dione …
Matched Iupac: … 1-(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)pyrrolidine-2,5-dione …
Clervonafusp alfa
Investigational
Matched Synonyms: … Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952 …
Hexamethonium
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by...
Experimental
Matched Iupac: … trimethyl[6-(trimethylazaniumyl)hexyl]azanium …
Matched Salts cas: … 55-97-0 …
Matched Salts cas: … 55-97-0 …
Ioflupane F-18
Investigational
Matched Synonyms: … 8-azabicyclo(3.2.1)octane-2-carboxylic acid, 8-(3-(fluoro-18f)propyl)-3-(4-iodophenyl)-, methyl ester ... Methyl (1s,3s,4s,5r)-8-(3-fluoranylpropyl)-3-(4-iodophenyl)-8-azabicyclo(3.2.1)octane-4-carboxylate ... 18fluorine-n-3-fluoropropyl-2beta-carbomethoxy-3beta-(4-iodophenyl) nortropane …
Matched Iupac: … methyl (1R,2S,3S,5S)-8-[3-(¹⁸F)fluoropropyl]-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate …
Matched Iupac: … methyl (1R,2S,3S,5S)-8-[3-(¹⁸F)fluoropropyl]-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate …
Ceclazepide
Investigational
Matched Synonyms: … (r)-1-(1-(4-acetoxy-3,3-dimethyl-2-oxo-butyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1h-benzo(e)(1,4)diazepin ... -3-yl)-3-(3-methylamino-phenyl)-urea ... -3-yl)-n'-(3-(methylamino)phenyl)- …
Matched Iupac: … -1,4-benzodiazepin-1-yl]-3-oxobutyl acetate ... 2,2-dimethyl-4-[(3R)-3-({[3-(methylamino)phenyl]carbamoyl}amino)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H …
Matched Iupac: … -1,4-benzodiazepin-1-yl]-3-oxobutyl acetate ... 2,2-dimethyl-4-[(3R)-3-({[3-(methylamino)phenyl]carbamoyl}amino)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H …
1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one
Experimental
Matched Name: … 1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one …
Matched Iupac: … 1-{3-oxo-3-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propyl}-3-phenyl-1,2-dihydroquinoxalin-2-one …
Matched Iupac: … 1-{3-oxo-3-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propyl}-3-phenyl-1,2-dihydroquinoxalin-2-one …
Nebicapone
Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg).
Investigational
Matched Iupac: … 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethan-1-one …
Matched Description: … Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state …
Matched Description: … Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state …
2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[2-METHYL-4-ISOXAZOLYL]-PHENOL
Experimental
Matched Name: … 2,6-DIMETHYL-1-(3-[3-METHYL-5-ISOXAZOLYL]-PROPANYL)-4-[2-METHYL-4-ISOXAZOLYL]-PHENOL …
Matched Iupac: … 4-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-2-methyl-1,3-oxazole …
Matched Iupac: … 4-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-2-methyl-1,3-oxazole …
Displaying drugs 4226 - 4250 of 10288 in total