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Displaying drugs 4301 - 4325 of 8859 in total
Experimental
Matched Iupac: … 4-(7-benzyl-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperazin-1-ium …
Sunvozertinib is under investigation in clinical trial NCT03974022 (Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)).
Investigational
Matched Synonyms: … N-{5-[(4-{[5-chloro-4-fluoro-2-(1-hydroxy-1-methylethyl)phenyl]amino}pyrimidin-2-yl)amino]-2-[(3R)-3- ... (dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl}prop-2-enamide …
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-9H-purin-9-yl}oxolan-2-yl]methoxy}phosphonic …
Poziotinib has been used in trials studying the treatment of Breast Cancer, Metastatic Breast Cancer, Increased Drug Resistance, Adenocarcinoma of Lung Stage IV, and Adenocarcinoma of Lung Stage IIIB, among others.
Investigational
Matched Iupac: … 1-[4-({4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}oxy)piperidin-1-yl]prop-2-en-1 …
Laninamivir has been used in trials studying the treatment of Influenza.
Investigational
Matched Iupac: … (2R,3R,4S)-4-carbamimidamido-2-[(1R,2R)-2,3-dihydroxy-1-methoxypropyl]-3-acetamido-3,4-dihydro-2H-pyran ... -6-carboxylic acid …
Experimental
Matched Name: … 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine …
Matched Iupac: … 4-{1-[(2,6-dichlorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}pyrimidin-2-amine …
AAV-RPE65 is an adenovirus associated viral vector serotype 5 containing the human RPE65 gene
Investigational
Experimental
Matched Name: … (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE …
Matched Iupac: … (4R,5R)-5-amino-1-[2-(2H-1,3-benzodioxol-5-yl)ethyl]-4-(2,4,5-trifluorophenyl)piperidin-2-one …
Experimental
Matched Iupac: … (1R,8S,11S)-3-(trifluoromethyl)tricyclo[6.2.1.0^{2,7}]undeca-2,4,6-trien-11-amine …
Investigational
Matched Synonyms: … 4-iodo-3-nitrobenzamide …
Matched Iupac: … 4-iodo-3-nitrobenzamide …
Seladelpar (MBX-8025) has been used in trials studying the treatment of Hyperlipidemia.
Investigational
Matched Iupac: … 2-(4-{[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl}-2-methylphenoxy)acetic acid …
Matched Salts cas: … 928821-40-3
Experimental
Matched Name: … N-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide …
Matched Iupac: … N-[(2,6-difluorophenyl)methyl]-4-sulfamoylbenzamide …
Investigational
Matched Synonyms: … 2'-Iodo-3'-hydroxy-4'-epi-4-demethoxydoxorubicin …
Matched Iupac: … (7S,9S)-7-{[(2R,3R,4R,5R,6S)-4,5-dihydroxy-3-iodo-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-9-(2-hydroxyacetyl …
Experimental
Matched Name: … Selenazole-4-carboxyamide-adenine dinucleotide …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4R,5R)-5-(4-carbamoyl ... -1,3-selenazol-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphinic acid …
Epigallo Catechin Gallate is under investigation in clinical trial NCT00799890 (Sunphenon in Progressive Forms of Multiple Sclerosis).
Investigational
Matched Synonyms: … (+)-catechin 3-gallate …
Matched Iupac: … (2R,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate …
Experimental
Matched Name: … 4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid …
Matched Iupac: … 4-[2,4-bis(3-nitrobenzamido)phenoxy]benzene-1,2-dicarboxylic acid …
Experimental
Matched Name: … 4-oxo-4,5-dihydro-1,2,5-thiadiazole-3-carboxylic acid …
Matched Iupac: … 4-hydroxy-1,2,5-thiadiazole-3-carboxylic acid …
Investigational
Matched Name: … 4-(2-(3-Propyl-(1,2,4)oxadiazol-5-yl)-vinyl)-benzene-1,2-diol …
Matched Iupac: … 4-[(1E)-2-(3-propyl-1,2,4-oxadiazol-5-yl)ethenyl]benzene-1,2-diol …
CF 101 (known generically as IB-MECA) is an anti-inflammatory drug for rheumatoid arthritis patients. Its novel mechanism of action relies on antagonism of adenoside A3 receptors. CF101 is supplied as an oral drug and has an excellent safety profile. It is also being considered for the treatment of other autoimmune-inflammatory...
Investigational
Matched Iupac: … (2S,3S,4R,5R)-3,4-dihydroxy-5-(6-{[(3-iodophenyl)methyl]amino}-9H-purin-9-yl)-N-methyloxolane-2-carboxamide …
Experimental
Matched Iupac: … (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-({[2-(decylamino)ethyl]sulfanyl}methyl)oxolane-3,4-diol …
Experimental
Matched Synonyms: … (S)-2-amino-3-(3-hydroxy-isoxazol-4-yl)propionic acid …
Matched Iupac: … (2S)-2-amino-3-(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid …
Experimental
Matched Iupac: … (2S,3R,5R,6R)-6-methyloxane-2,3,5-triol …
SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.
Investigational
Matched Synonyms: … 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole …
Matched Iupac: … 1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl]-1H-imidazole …
In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Synonyms: … 3-(2-aminobutyl)indole …
Matched Iupac: … 1-(1H-indol-3-yl)butan-2-amine …
Matched Description: … Instead, the effects of αET, a tryptamine derivative, more closely resemble the amphetamine derived drug 3,4
Matched Salts cas: … 118-68-3
Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
Investigational
Displaying drugs 4301 - 4325 of 8859 in total