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Displaying drugs 4326 - 4350 of 8265 in total

TRX-518

Investigational

RGX-501

RGX-501 is an adeno-associated virus vector 8 (AAV8)-mediated gene therapy that delivers a functional copy of the human low-density lipoprotein receptor (LDLR) gene to liver cells. It is being investigated for the treatment of homozygous familial hypercholesterolemia.
Investigational

LJP-539

Investigational

AMG-553

AMG-553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of autologous T-cells with a self-inactivating human immunodeficiency virus-1 based lentiviral vector.
Investigational

TC-5231

TC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder). TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than Inversine.
Investigational

HZT-501

HZT-501 is under investigation by Horizon Therapeutics, Inc., a privately held biopharmaceutical company. It has entered Phase 3 clinical trials in March 2007 for reduction of the risk of development of ibuprofen-associated upper gastrointestinal (i.e., gastric and/or duodenal) ulcers. HZT-501 is a combination product including ibuprofen and the acid reducing...
Investigational

ABT-510

ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and slows tumor growth. It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.
Investigational
Matched Iupac: … (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S,3S)-2-[(2S)-2-[(2S,3R)-3-hydroxy-2-[(2R,3S)-3-methyl …

CAN-508

Experimental
Matched Iupac: … 4-[(1E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol …

GS-5745

GS-5745 has been used in trials studying the treatment of Tumors, Breast Cancer, Crohn's Disease, Colorectal Cancer, and Pancreatic Cancer, among others.
Investigational

AGG-523

AGG-523 is under investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects with osteoarthritis).
Investigational
Matched Iupac: … (4S)-4-({[1,1'-biphenyl]-4-yl}formamido)-4-{[1-(4-fluorophenyl)-2-methylpropan-2-yl]carbamoyl}butanoic …

APR-548

APR-548 is an analog of eprenetapopt and a reactivator of mutant p53.
Investigational

GTP-506

GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational

Cordycepin Triphosphate

Experimental
Matched Iupac: … ({[({[(2S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …

dATP

Experimental
Matched Synonyms: … Deoxyadenosine 5'-triphosphate ... 2'-Deoxyadenosine 5'-triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy …

2-Amino-Adenosine

Experimental
Matched Iupac: … (2R,3S,4R,5R)-4-amino-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol …

5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine

Experimental
Matched Name: … 5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine …
Matched Iupac: … 5-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methoxy)quinazoline-2,4-diamine …

N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE

Experimental
Matched Name: … N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE …
Matched Iupac: … 3-({2',4'-difluoro-4-hydroxy-5-iodo-[1,1'-biphenyl]-3-yl}formamido)propanoic acid …

Triacetylchitotriose

Experimental
Matched Iupac: … -(hydroxymethyl)oxan-3-yl]oxy}-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl ... N-[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4R,5R,6S)-5-acetamido-6-{[(2R,3S,4R,5R,6R)-5-acetamido-4,6-dihydroxy-2 …

Cannabinol

Cannabinol (CBN) is a physiologically inactive constituent of Cannabis sativa.
Experimental
Investigational

2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile

Experimental
Matched Name: … 2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile …
Matched Iupac: … 2-[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile …

HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM

Experimental
Matched Name: … HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM …
Matched Iupac: … (2Z)-N-(3-nitrophenyl)-4-{3-[(1H-1,2,4-triazol-1-yl)methyl]phenyl}-2,5-dihydropyrimidin-2-imine …

Quilseconazole

Investigational
Matched Synonyms: … .-(1h-tetrazol-1-ylmethyl)-5-(4-(trifluoromethoxy)phenyl)-, (.alpha.r)- …
Matched Iupac: … (2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-{5-[4-(trifluoromethoxy)phenyl …

N-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide

Experimental
Matched Name: … N-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide …
Matched Iupac: … N-[(2S)-2-(1H-indol-5-yl)butyl]-4-sulfamoylbenzamide …

4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACID

Experimental
Matched Name: … 4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACID …
Matched Iupac: … 4-acetamido-3-hydroxy-5-nitrobenzoic acid …

4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID

Experimental
Matched Name: … 4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID …
Matched Iupac: … 3-amino-4-acetamido-5-hydroxybenzoic acid …
Displaying drugs 4326 - 4350 of 8265 in total