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Displaying drugs 4326 - 4350 of 7888 in total

BM-3103

Investigational
Matched Synonyms: … 4-Hydroxy-4'-methyoxytolan ... 4-Hydroxy-4′-methoxytolan …

Nutlin-3

Nutlin-3 is a small molecule inhibitor that targets p53-Mdm2 interaction.
Investigational
Matched Synonyms: … 2-piperazinone, 4-(((4r,5s)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl …
Matched Iupac: … 4-[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazole-1- …

PD-169316

PD-169316 is a p38 MAP kinase inhibitor.
Investigational
Matched Synonyms: … 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1h-imidazole ... Pyridine, 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-5-yl)- ... Pyridine, 4-(5-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-4-yl)- …
Matched Iupac: … 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]pyridine …

Myricetin

Experimental
Matched Synonyms: … 3,3',4',5,5',7-Hexahydroxyflavone ... 3,5,7,3',4',5'-Hexahydroxyflavone ... 3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-one …
Matched Iupac: … 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one …

Balhimycin

Balhimycin is a novel glycopeptide antibiotic.
Experimental
Matched Iupac: … 2-[(4-amino-4,6-dimethyl-5-oxooxan-2-yl)oxy]-22-(carbamoylmethyl)-5,47-dichloro-18,32,35,37-tetrahydroxy ... -19-[4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-48-{[3,4,5-trihydroxy-6-(hydroxymethyl …

MK-4721

MK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients with all stages of prostate, pancreatic and bladder cancers.
Investigational

(4s)-5-Fluoro-L-Leucine

Experimental
Matched Iupac: … (2S,4S)-2-amino-5-fluoro-4-methylpentanoic acid …

2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE

Experimental

Ciluprevir

The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Investigational
Matched Iupac: … yl}quinolin-4-yl)oxy]-2,15-dioxo-3,16-diazatricyclo[14.3.0.0^{4,6}]nonadec-7-ene-4-carboxylic acid ... ,14S,18R)-14-{[(cyclopentyloxy)carbonyl]amino}-18-[(7-methoxy-2-{2-[(propan-2-yl)amino]-1,3-thiazol-4- …

RBIO-101

RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.
Investigational

AV-101

AV-101 has been used in trials studying the treatment of Neuropathic Pain.
Investigational
Matched Synonyms: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid ... L-4-CL-KYN ... 4-chlorokynurenine …
Matched Iupac: … (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid …

Larcaviximab

Investigational

8-Bromoadenosine-5'-Diphosphate

Experimental
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …

Dersimelagon

Investigational
Matched Synonyms: … 1-(2-((3s,4r)-1-((3r,4r)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)pyrrolidine-3-carbonyl)-4-(methoxymethyl ... 4-piperidinecarboxylic acid, 1-(2-((3s,4r)-1-(((3r,4r)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)-3-pyrrolidinyl ... )pyrrolidin-3-yl)-5-(trifluoromethyl)phenyl)piperidine-4-carboxylic acid …
Matched Iupac: … 1-{2-[(3S,4R)-1-[(3R,4R)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)pyrrolidine-3-carbonyl]-4-(methoxymethyl ... )pyrrolidin-3-yl]-5-(trifluoromethyl)phenyl}piperidine-4-carboxylic acid …

AZD2066

Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …

MBS-2320

Investigational
Matched Synonyms: … (1,1'-BIPHENYL)-4-SULFONAMIDE, 4'-CHLORO-2'-CYANO-N-(TRANS-4-HYDROXY-4-METHYLCYCLOHEXYL)- ... 4'-chloro-2'-cyano-N-(trans-4-hydroxy-4-methylcyclohexyl)-biphenyl-4-sulfonamide ... 1-METHYL-TRANS-4-(((4'-CHLORO-2'-CYANO-1,1'-BIPHENYL-4-YL)SULFONYL)AMINO)CYCLOHEXANOL …
Matched Iupac: … 4'-chloro-2'-cyano-N-[(1r,4r)-4-hydroxy-4-methylcyclohexyl]-[1,1'-biphenyl]-4-sulfonamide …

AL-4623

Experimental
Matched Iupac: … (4R)-4-(ethylamino)-2-(2-methoxyethyl)-1,1-dioxo-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …

OSI-461

OSI-461 is a second-generation molecule belonging to a new class of drugs termed selective apoptotic anti-neoplastic drugs (SAANDs).
Investigational

MRK-409

MRK-409 is a GABA-A receptor agonist .
Experimental
Matched Iupac: … 5-({[7-cyclobutyl-3-(2,6-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]oxy}methyl)-1-methyl-1H …

PCS-499

PCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients).
Investigational

VS-4718

VS-4718 is under investigation in clinical trial NCT02215629 (Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia).
Investigational
Matched Iupac: … 2-[(2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}-5-(trifluoromethyl)pyridin-4-yl)amino]-N-methylbenzamide …

YK-4-279

Investigational
Matched Synonyms: … (S)-YK-4-279 ... 4,7-dichloro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-1H-indol-2-one …
Matched Name: … YK-4-279 …

MK-4830

MK-4830 is a monoclonal antibody that targets the myeloid-specific immunoglobulin-like transcript (ILT) 4 receptor.
Investigational
Matched Description: … 4830 is a monoclonal antibody that targets the myeloid-specific immunoglobulin-like transcript (ILT) 4 …

PMC-403

PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational

AVX-470

AVX-470 is an anti-tumor necrosis factor (TNF) polyclonal antibody (bovine).
Investigational
Displaying drugs 4326 - 4350 of 7888 in total