Displaying drugs 4326 - 4350 of 11607 in total
Rocatinlimab
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Description: … In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with ... Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe …
CN-201
CN-201 is a humanized anti-CD3/CD19 bispecific antibody.
Investigational
Matched Description: … CN-201 is a humanized anti-CD3/CD19 bispecific antibody. …
Cibisatamab
Investigational
Acimtamig
Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Dipraglurant
Dipraglurant has been used in trials studying the treatment of Parkinson's Disease. It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).
Investigational
Matched Iupac: … 2-(4-{6-fluoroimidazo[1,2-a]pyridin-2-yl}but-1-yn-1-yl)pyridine …
Matched Description: … It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). …
Matched Description: … It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM). …
Onercept
Investigational
Gentulizumab
Investigational
Galiximab
Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug.
Investigational
Matched Description: … Galiximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. …
Decoglurant
Decoglurant has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … 5-{2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl}pyridin- …
Odronextamab
Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody currently evaluated for the treatment of relapsed/refractory (R/R) B-Cell non-Hodgkin lymphoma (NHL).[A254187,A254197] Preliminary studies have shown that in patients with R/R NHL, the use of odronextamab does not lead to the development of neurologic toxicity; however, it can...
Investigational
Matched Description: … with B-cell non-Hodgkin lymphoma, odronextamab elicited a durable response with a manageable safety ... Odronextamab is a hinge-stabilized, fully human immunoglobulin G4 (IgG4)-based CD20×CD3 bispecific antibody ... of neurologic toxicity; however, it can lead to the development of cytokine release syndrome (CRS), a …
Plamotamab
Plamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL)).
Investigational
Crefmirlimab
Crefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.
Investigational
Giloralimab
Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Investigational
Coagulin-B
Coagulin-B is an adeno-associated viral vector expressing human blood-coagulation Factor IX.[A259038, A259043] It was previously investigated for the treatment of hemophilia; however, the manufacturing company discontinued the Phase I trial in 2004, halting its further development and investigation.
Investigational
BI-836858
Investigational
CLL1-CD33 compound chimeric antigen receptor T cells
Investigational
BI-836826
Investigational
Cevostamab
Investigational
Dapirolizumab pegol
Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety Study of Dapirolizumab Pegol (DZP) in Systemic Lupus Erythematosus).
Investigational
Matched Description: … Dapirolizumab pegol is under investigation in clinical trial NCT02804763 (A Phase 2 Efficacy and Safety …
QXL138AM
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Matched Description: … QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused …
Tenofovir
Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and...
Experimental
Investigational
Matched Description: … [A37693] In the most strict sense and due to the fact that it presents a phosphate group bound to the …
DR-01
DR-01 is a monoclonal antibody directed against human CD94.
Investigational
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Roledumab
Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).
Investigational
Displaying drugs 4326 - 4350 of 11607 in total