Displaying drugs 4401 - 4425 of 9292 in total
N,N-dimethylarginine
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a...
Experimental
Matched Synonyms: … N(5)-((Dimethylamino)iminomethyl)-L-ornithine ... dimethyl-L-arginine ... L-NG,NG-dimethylarginine …
Matched Iupac: … (2S)-2-amino-5-[(E)-[amino(dimethylamino)methylidene]amino]pentanoic acid …
Matched Description: … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and ... continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine …
Matched Iupac: … (2S)-2-amino-5-[(E)-[amino(dimethylamino)methylidene]amino]pentanoic acid …
Matched Description: … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and ... continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine …
Nesolicaftor
Nesolicaftor (PTI-428) is under investigation in clinical trial NCT03258424 (Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis on KALYDECO® as Background Therapy).
Investigational
Matched Synonyms: … N-(trans-3-(5-((R)-1-hydroxyethyl)-1,3,4-oxadiazol-2-yl)cyclobutyl)-3-phenylisoxazole-5-carboxamide …
Matched Iupac: … 3-phenyl-N-[(1r,3r)-3-{5-[(1R)-1-hydroxyethyl]-1,3,4-oxadiazol-2-yl}cyclobutyl]-1,2-oxazole-5-carboxamide …
Matched Iupac: … 3-phenyl-N-[(1r,3r)-3-{5-[(1R)-1-hydroxyethyl]-1,3,4-oxadiazol-2-yl}cyclobutyl]-1,2-oxazole-5-carboxamide …
LL-37
LL-37 is a human cathelicidin that inhibits viral replication and while also playing a role in host defense against infection.
Investigational
1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE)
Experimental
Matched Name: … 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL …
Matched Iupac: … (2S)-2-acetamido-4-methyl-N-[(2S)-4,4,4-trifluoro-3-oxo-1-phenylbutan-2-yl]pentanamide …
Matched Iupac: … (2S)-2-acetamido-4-methyl-N-[(2S)-4,4,4-trifluoro-3-oxo-1-phenylbutan-2-yl]pentanamide …
AZD-6280
AZD6280 has been used in trials studying the basic science of Anxiety.
Investigational
Matched Iupac: … 4-amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboxamide …
PAT-SM6
Investigational
CDX-6210
CDX-6210 is a modified version of a leucine decarboxylase enzyme from Planctomycetaceae bacterium.
Investigational
CDX-6512
CDX-6512 is a modified, gastrointestinal-stable bacterial leucine decarboxylase. Developed by Codexis, it is being investigated for the treatment of homocystinuria And Maple Syrup Urine Disease.[L46651, L46656]
Investigational
Modified Acarbose Pentasaccharide
Experimental
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(1R,4S,5S,6R)-4-{[(2R,3S,4S,5R,6R)-6-{[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl ... )-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxan-3-yl]oxy}-4,5-dihydroxy-2 ... -methyloxan-3-yl]amino}-5,6-dihydroxy-2-(hydroxymethyl)cyclohex-2-en-1-yl]oxy}-6-methyloxane-3,4,5-triol …
Inhibitor BEA388
Experimental
Matched Synonyms: … [5-(2-hydroxy-indan-1-ylcarbamoyl)-3,4-dihydroxy-2,5-[dibenzyl-oxy]-pentanoyl]-valinyl-amido-methane …
2'-Fucosyllactose
2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy).
Investigational
Matched Iupac: … (2R,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy ... -6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,3,5,6-tetrahydroxyhexanal …
H-89
Experimental
Matched Synonyms: … N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide …
Matched Iupac: … N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide …
Matched Iupac: … N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide …
4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole
Experimental
Matched Name: … 4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole …
Matched Iupac: … 4-ethyl-6-[4-(1H-imidazol-4-yl)-1H-pyrazol-3-yl]benzene-1,3-diol …
Matched Iupac: … 4-ethyl-6-[4-(1H-imidazol-4-yl)-1H-pyrazol-3-yl]benzene-1,3-diol …
Certepetide
Investigational
Matched Synonyms: … L-Cysteinamide, N-acetyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-lysylglycyl-L-prolyl-L-α-aspartyl ... N-Acetyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-lysylglycyl-L-prolyl-L-α-aspartyl-L-cysteinamide, ... S1,S9-cyclo(N-acetyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-lysylglycyl-L-prolyl-L-α-aspartyl-L-cysteinamide …
5-amino-1,3,4-thiadiazole-2-thiol
ATT has been investigated in Pulmonary Tuberculosis.
Investigational
Matched Name: … 5-amino-1,3,4-thiadiazole-2-thiol …
Matched Iupac: … 5-amino-1,3,4-thiadiazole-2-thiol …
Matched Iupac: … 5-amino-1,3,4-thiadiazole-2-thiol …
LB-100
LB-100 is under investigation in clinical trial NCT03886662 (A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)).
Investigational
Matched Iupac: … (1R,4S)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid …
LV-FAH
Investigational
4-(Aminosulfonyl)-N-[(2,4,6-Trifluorophenyl)Methyl]-Benzamide
Experimental
Matched Name: … 4-(Aminosulfonyl)-N-[(2,4,6-Trifluorophenyl)Methyl]-Benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(2,4,6-trifluorophenyl)methyl]benzamide …
Matched Iupac: … 4-sulfamoyl-N-[(2,4,6-trifluorophenyl)methyl]benzamide …
Ribavirin elaidate
Investigational
Matched Synonyms: … Ribavirin-5'-elaidic acid ester ... 1h-1,2,4-triazole-3-carboxamide, 1-(5-o-((9e)-1-oxo-9-octadecen-1-yl)-.beta.-d-ribofuranosyl)- …
Matched Iupac: … [(2R,3S,4R,5R)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (9E)-octadec-9-enoate …
Matched Iupac: … [(2R,3S,4R,5R)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl (9E)-octadec-9-enoate …
Etazolate
EHT 0202 is developed to treat neurodegenerative disorders by ExonHit Therapeutics.
Investigational
Matched Synonyms: … 1H-PYRAZOLO(3,4-B)PYRIDINE-5-CARBOXYLIC ACID, 1-ETHYL-4-((1-METHYLETHYLIDENE)HYDRAZINO)-, ETHYL ESTER …
Pyrroloquinoline Quinone
A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. [PubChem]
Experimental
Matched Iupac: … 4,5-dioxo-1H,4H,5H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid …
Matched Description: … A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl …
Matched Description: … A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl …
Metizoline
Experimental
Matched Iupac: … 2-[(2-methyl-1-benzothiophen-3-yl)methyl]-4,5-dihydro-1H-imidazole …
4-AMINO-5-(2-METHYLPHENYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE
Experimental
Matched Name: … 4-AMINO-5-(2-METHYLPHENYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE …
Matched Iupac: … 4-amino-3-(2-methylphenyl)-4,5-dihydro-1H-1,2,4-triazole-5-thione …
Matched Iupac: … 4-amino-3-(2-methylphenyl)-4,5-dihydro-1H-1,2,4-triazole-5-thione …
Displaying drugs 4401 - 4425 of 9292 in total