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Displaying drugs 4401 - 4425 of 5619 in total
Investigational
Matched Synonyms: … 2-propenamide, n-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl)amino)-3-methylphenyl)- ... N-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl)amino)-3-methylphenyl)-2-propenamide …
Matched Iupac: … N-(2-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}-3-methylphenyl)prop-2-enamide …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
Investigational
Matched Synonyms: … (3-chloro-4-fluorophenyl)-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1-yl)methanone ... 4-piperidinemethanamine, 1-(3-chloro-4-fluorobenzoyl)-4-fluoro-n-((5-methyl-2-pyrimidinyl)methyl)- ... 3-chloro-4-fluorophenyl-(4-fluoro-4-(((5-methylpyrimidin-2-ylmethyl)amino)methyl)piperidin-1yl)methanone …
Matched Iupac: … {[1-(3-chloro-4-fluorobenzoyl)-4-fluoropiperidin-4-yl]methyl}[(5-methylpyrimidin-2-yl)methyl]amine …
Experimental
Matched Name: … (3S)-N-(3-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE …
Matched Iupac: … (3S)-N-(3-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide …
Experimental
Matched Name: … 3-chloro-5-[2-chloro-5-(1H-indazol-3-ylmethoxy)phenoxy]benzonitrile …
Matched Iupac: … 3-chloro-5-{2-chloro-5-[(1H-indazol-3-yl)methoxy]phenoxy}benzonitrile …
Experimental
Matched Name: … 1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE …
Matched Iupac: … 1-(3-hydroxypropyl)-2-(3-nitrobenzamido)-1H-1,3-benzodiazol-5-yl 2,2-dimethylpropanoate …
Experimental
Matched Name: … 2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM …
Matched Iupac: … 2-[4-(dimethylamino)phenyl]-6-hydroxy-3-methyl-1,3-benzothiazol-3-ium …
Experimental
Matched Name: … 3-(2-AMINO-6-BENZOYLQUINAZOLIN-3(4H)-YL)-N-CYCLOHEXYL-N-METHYLPROPANAMIDE …
Matched Iupac: … 3-(2-amino-6-benzoyl-3,4-dihydroquinazolin-3-yl)-N-cyclohexyl-N-methylpropanamide …
Experimental
Matched Name: … 3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline …
Matched Iupac: … (2E)-3-{4-[(3-aminophenyl)sulfanyl]-2,3-bis(trifluoromethyl)phenyl}-1-(morpholin-4-yl)prop-2-en-1-one …
Experimental
Matched Name: … (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate …
Matched Iupac: … (3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propyl 2,2-dimethylpropanoate …
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Synonyms: … 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate …
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate …
Matched Description: … Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Experimental
Matched Synonyms: … Phenyl (3S)-3-({N-[(benzyloxy)carbonyl]-L-phenylalanyl}amino)-5-phenyl-1-pentanesulfonate …
Matched Iupac: … benzyl N-[(1S)-1-{[(3S)-1-(phenoxysulfonyl)-5-phenylpentan-3-yl]carbamoyl}-2-phenylethyl]carbamate
AT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Investigational
Matched Synonyms: … 4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide …
Matched Iupac: … 4-(2,6-dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide …
Matched Description: … It is developed by Astex for the treatment of solid tumours and haematological malignancies. …
Carbazochrome is a hemostatic agent that promotes clotting, preventing blood loss from open wounds. It is an oxidation product of adrenaline which enhances the microcirculatory tone . In the future this may prevent excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on effectiveness and severity...
Experimental
Withdrawn
Matched Synonyms: … 3-Hydroxy-1-methyl-5,6-inodlindionsemicarbazon …
Matched Iupac: … {[(5Z)-3-hydroxy-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indol-5-ylidene]amino}urea …
Matched Description: … , but research on effectiveness and severity of side effects remains inconclusive. ... In the future this may prevent excessive blood flow during surgical operations and the treatment of hemorrhoids ... for use in the treatment of non-surgical acute uncomplicated hemorrhoids in a mixture with [DB13124], and
Matched Categories: … Blood and Blood Forming Organs …
Aticaprant has been used in trials studying the health services research and basic science of Anxiety Disorders and Alcohol Dependence.
Investigational
Matched Synonyms: … BENZAMIDE, 4-(4-(((2S)-2-(3,5-DIMETHYLPHENYL)-1-PYRROLIDINYL)METHYL)PHENOXY)-3-FLUORO- …
Matched Iupac: … 4-(4-{[(2S)-2-(3,5-dimethylphenyl)pyrrolidin-1-yl]methyl}phenoxy)-3-fluorobenzamide …
Matched Description: … Disorders and Alcohol Dependence. ... Aticaprant has been used in trials studying the health services research and basic science of Anxiety …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Illicit
Vet approved
Matched Synonyms: … 17beta-Hydroxyandrosta-1,4-dien-3-one 10-undecenoate …
Matched Iupac: … (1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide …
Matched Iupac: … 7-chloro-3-methyl-4H-1lambda6,2,4-benzothiadiazine-1,1-dione …
Matched Description: … and does not have chloriuretic or natriuretic activity. ... [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular ... and electrolyte disturbances. …
Matched Categories: … Thiazide Derivatives …
Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Synonyms: … (Z)-4-(3-(2-Chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … It is an antagonist at D1 and D2 dopamine receptors. ... Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. ... hydroxytryptamine receptor 2A, D(1B) dopamine receptor, D(2) dopamine receptor, D(1A) dopamine receptor, and
Matched Salts name: … Zuclopenthixol acetate
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Experimental
Matched Synonyms: … (2S)-2-amino-3-(4-hydroxyphenyl)propanamide …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxyphenyl)propanamide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Vanoxerine is a highly selective dopamine transporter antagonist. It was synthesized in the late 1970s and developed as a potential treatment for depression. Vanoxerine was later evaluated as a potential treatment for cocaine addiction due to its ability to block dopamine reuptake with a slower dissociation rate than cocaine. Although...
Investigational
Matched Synonyms: … 1-(2-(bis(p-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine …
Matched Iupac: … 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine …
Matched Description: … It was synthesized in the late 1970s and developed as a potential treatment for depression. ... [A248555] Vanoxerine is an investigational drug and has not been approved for therapeutic use. ... [A248585] More recently, vanoxerine was tested as a potential anti-arrhythmic and anti-atrial fibrillatory …
Matched Salts name: … Vanoxerine hydrochloride
Experimental
Matched Name: … 3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE …
Matched Iupac: … 3-(2-aminoquinazolin-6-yl)-4-methyl-N-[3-(trifluoromethyl)phenyl]benzamide …
Experimental
Matched Name: … 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol …
Matched Iupac: … 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol …
Investigational
Matched Synonyms: … -4-yl)amino)imidazo[1,2-a]pyridin-3-yl)ethynyl)benzamide ... 8-[(1-methyl-1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl]ethynyl]- ... Benzamide, N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-[2-[ …
Matched Iupac: … -1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl}ethynyl)benzamide ... N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl …
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
Experimental
Illicit
Matched Synonyms: … 3-dimethylamino-1,1-bis(2-thienyl)-1-butene ... 3-dimethylamino-1,1-di-(2'-thienyl)-1-butene ... N,N,1-trimethyl-3,3-di-2-thienylallylamine …
Matched Iupac: … [4,4-bis(thiophen-2-yl)but-3-en-2-yl]dimethylamine …
Matched Description: … Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid …
Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant activity. It is not approved in Canada or America.
Experimental
Matched Synonyms: … 1-(2-cyanoethyl)-7-chloro-3-hydroxy-5-(2'-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one ... 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propanenitrile ... 7-chloro-5-(o-fluorophenyl)-2,3-dihydro-3-hydroxy-2-oxo-1H-1,4-benzodiazepine-1-propionitrile …
Matched Iupac: … 3-[7-chloro-5-(2-fluorophenyl)-3-hydroxy-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-1-yl]propanenitrile …
Matched Description: … Cinolazepam is a benzodiazepine derivative with anxiolytic, anticonvulsant, sedative and skeletal muscle …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third ... degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. …
Matched Salts cas: … 38363-32-5 …
Matched Categories: … penbutolol and other diuretics ... Adrenergic beta-Antagonists ... Beta Blocking Agents, Non-Selective …
Matched Products: … BETAPRESSİN 40 MG FİLM TABLET, 30 TABLET …
Displaying drugs 4401 - 4425 of 5619 in total