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Displaying drugs 426 - 450 of 742 in total
PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …
Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 ... .gamma.4-chain), disulfide with human-mus musculus monoclonal js004 .kappa. …
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND 3'-LTR/PO ... , SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER THE ... AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING …
Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …
Matched Description: … It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing …
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta ... rAAV2/1 Hex alpha and beta …
Ocaratuzumab is a humanized monoclonal antibody directed against CD20. It is being investigated for cancers and autoimmune disorders.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1, Bp35, leukocyte ... surface antigen Leu-16, membrane-spanning 4-domains subfamily A member 1)) …
Matched Description: … It is being investigated for cancers and autoimmune disorders. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men).
Investigational
Matched Synonyms: … Human metastin 45-54 ... Kisspeptin-10 (human) …
Matched Description: … Kisspeptin-10 is under investigation in clinical trial NCT03771326 (KP-10 and Insulin Secretion in Men …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Investigational
Matched Synonyms: … IgG1 antibody inhibiting PD-L1 and CTLA-4 ... RECEPTOR HER2 DOMAIN IV)(HUMAN-MUS MUSCULUS MONOCLONAL RHUMAB 4D5 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS ... FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific …
Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others.
Investigational
Matched Synonyms: … Interleukin 4 human ... Interleukin 4 (human) ... Interleukin-4 (human; nonglycosylated) …
Matched Description: … treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and
Matched Categories: … Interleukin-4, antagonists & inhibitors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Experimental
Matched Synonyms: … Human EGF ... Human urogastrone ... Epidermal growth factor (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … REGEN-D 60 MCG JEL, 1 ADET ... REGEN-D 150 MCG JEL, 1 TÜP ... HEBERPROT-P 75 MCG ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage III Unresectable Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tigit) (human-mus musculus monoclonal bgb-a1217 .gamma.1-chain ... Immunoglobulin g1-kappa, anti-(homo sapiens tigit (t-cell immunoreceptor with ig domain and itim, v-set ... ig member 9, vsig9, v-set and transmembrane member 3, vstm3)), humanized monoclonal antibody (ociperlimab …
TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … human PKP2 gene ... A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … the wild-type human PKP2 gene. ... TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and
rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide...
Investigational
Matched Synonyms: … Recombinant human mannan-binding protein ... Recombinant human mannose-binding lectin …
Matched Description: … rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections …
Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human interleukin 23) (human monoclonal medi2070 heavy chain), disulfide with ... human monoclonal medi2070 .lambda. …
Matched Description: … Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study …
Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN VIMENTIN) (HUMAN-MUS MUSCULUS .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS …
Matched Description: … Safety of Burfiralimab (Hzvsf-v13) and DMRD (Disease-modifying Antirheumatic Drug)). ... Burfiralimab is under investigation in clinical trial NCT06306339 (A Study to Assess the Efficacy and
Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receptor 4)) (human monoclonal trm-1 heavy …
Matched Description: … Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … (1-106) FUSION PROTEIN WITH HUMAN IMMUNOGLOBULIN G1 ... (L120>A,L121>E,G123>A,A216>S,P217>S)-TACI (TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR, TUMOR NECROSIS ... ) fusion protein with immunoglobulin g1, (human rc18 fc fragment), dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN
Matched Description: … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Investigational
Matched Synonyms: … -6, Epstein Barr virus, and adenovirus ... Allogeneic multi-virus specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus …
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human tissue factor pathway inhibitor) (human monoclonal 1093884 .gamma.2-chain ... ), disulfide with human monoclonal 1093884 .lambda. ... Human tissue factor pathway inhibitor-neutralizing antibody (bay 1093884) …
Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH-LIGAND 1) (HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN ... ), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND CLEAVABLE MOIETY PROTEASE SUBSTRATE-CONTAINING ... ) FUSION PROTEIN WITH HUMAN MONOCLONAL C …
Matched Description: … Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). ... Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor …
Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and Safety of CSL312 on Catheter-associated Blood Clot Formation in Subjects With Cancer Who Receive Chemotherapy Through a PICC Line).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(human blood-coagulation factor viia) (human monoclonal CSL312 gamma4-chain), ... disulfide with human monoclonal CSL312 lambda-chain, dimer …
Matched Description: … Garadacimab is under investigation in clinical trial NCT04281524 (A Clinical Study to Test the Efficacy and
Investigational
Matched Synonyms: … .1-chain), disulfide with human monoclonal isu104 .lambda. ... Immunoglobulin g1, anti-(human epidermal growth factor receptor her3) (human monoclonal isu104 .gamma …
Investigational
Matched Synonyms: … Immunoglobulin igg4, anti-(human cd47) (human monoclonal srf231 .gamma.4-chain), disulfide with human
Zanolimumab is a fully human monoclonal antibody directed against CD4.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, ANTI-(HUMAN CD4 ANTIGEN) (HUMAN MONOCLONAL 6G5 HEAVY CHAIN), DISULPHIDE WITH HUMAN MONOCLONAL …
Matched Description: … Zanolimumab is a fully human monoclonal antibody directed against CD4. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 426 - 450 of 742 in total