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Displaying drugs 4701 - 4725 of 9148 in total
N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding...
Investigational
Withdrawn
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Experimental
Matched Iupac: … tetrasodium 2-({2-[bis(carboxylatomethyl)amino]ethyl}(carboxylatomethyl)amino)acetate …
GO-203-2C is under investigation in clinical trial NCT02204085 (A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Investigational
Matched Iupac: … ]pentylidene]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene]amino ... }-1-hydroxypentylidene]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene]amino}-1-hydroxypentylidene ... ]amino}-1-hydroxyhexylidene]amino}-3-(C-hydroxycarbonimidoyl)propanoic acid ... ]amino}-1-hydroxypentylidene]amino}-6,9-dihydroxy-7-[2-(C-hydroxycarbonimidoyl)ethyl]-1,2-dithia-5,8- ... diazacycloundeca-5,8-dien-4-yl](hydroxy)methylidene}amino)-1-hydroxypentylidene]amino}-1-hydroxypentylidene …
Experimental
Matched Iupac: … (2S)-2-amino-6-{[(1R)-1-carboxyethyl]amino}hexanoic acid …
Experimental
Matched Iupac: … (7R,8S)-8-amino-7-{[(phosphonooxy)carbonyl]amino}nonanoic acid …
Dapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures.
Investigational
Matched Iupac: … 4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzonitrile …
Experimental
Matched Iupac: … [4-({2-[(4-arsonophenyl)amino]ethyl}amino)phenyl]arsonic acid …
Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections. It binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Iupac: … [(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Apolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bivatuzumab (previously BIWA 4) is a humanized monoclonal antibody against CD44 v6. [A31688,A31689]
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Categories: … Amino Acids, Peptides, and Proteins …
Conatumumab has been used in trials studying the treatment of Sarcoma, Lymphoma, Oncology, Colon Cancer, and Rectal Cancer, among others.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bapineuzumab has been investigated for the treatment of Alzheimer's Disease.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Onartuzumab has been used in trials studying the treatment of Neoplasms, Lung Cancer, Glioblastoma, Gastric Cancer, and Colorectal Cancer, among others.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dalotuzumab has been investigated for the treatment of Breast Cancer, Non Small Cell Lung Cancer, and Metastatic Colorectal Cancer.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Emibetuzumab has been used in trials studying the treatment of Advanced Cancer, Renal Cell Carcinoma, Hepatocellular Cancer, Gastric Adenocarcinoma, and Non-Small Cell Lung Cancer, among others.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Landogrozumab has been used in trials studying the treatment of Advanced Cancer, Muscular Atrophy, and Pancreatic Cancer.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Anrukinzumab has been used in trials studying the diagnostic of Asthma.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vanucizumab has been used in trials studying the treatment of ColoRectal Cancer and Advanced/Metastatic Solid Tumors.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and Advanced Gastrointestinal Carcinoma, among others.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lumretuzumab has been used in trials studying the treatment of Neoplasms, Breast Cancer, Squamous Non-Small Cell Lung Cancer, and Non-Squamous Non-Small Cell Lung Cancer.
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 4701 - 4725 of 9148 in total