Displaying drugs 451 - 475 of 1067 in total
Docetaxel
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
N-(Phosphonoacetyl)-L-Ornithine
Experimental
Matched Name: … N-(Phosphonoacetyl)-L-Ornithine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Folic acid
Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Pteroyl-L-glutamate ... Pteroyl-L-glutamic acid ... N-pteroyl-L-glutamic acid …
Matched Description: … As humans are unable to synthesize folic acid endogenously, diet and supplementation is necessary to ... cofactor for enzymes involved in DNA and RNA synthesis. ... Levoleucovorin and leucovorin are analogs of tetrahydrofolate (THF) and are able to bypass DHFR reduction …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... and Succinic Acid ... Threonate and Succinic Acid …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... ferrous sulfate and folic acid ... iron, multivitamins and folic acid …
Matched Description: … As humans are unable to synthesize folic acid endogenously, diet and supplementation is necessary to ... cofactor for enzymes involved in DNA and RNA synthesis. ... Levoleucovorin and leucovorin are analogs of tetrahydrofolate (THF) and are able to bypass DHFR reduction …
Matched Mixtures name: … Multi Vitamin and Mineral vitamin ... and Succinic Acid ... Threonate and Succinic Acid …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... ferrous sulfate and folic acid ... iron, multivitamins and folic acid …
Acacia
Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …
Tryptophanamide
Experimental
Matched Synonyms: … L-tryptophan amide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sotigalimab
Sotigalimab is under investigation in clinical trial NCT03123783 (CD40 Agonistic Antibody APX005M in Combination With Nivolumab).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (270-GLUTAMIC ACID, C-TERMINAL-LYSINE-CLIPPED), ANTI-(HUMAN CD40 ANTIGEN) (HUMAN-ORYCTOLAGUS ... CUNICULUS MONOCLONAL APX005M .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-ORYCTOLAGUS CUNICULUS MONOCLONAL …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Exlinkibart
Investigational
Matched Synonyms: … Immunoglobulin G1 (de-236-glycine,267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis ... factor receptor TNFRSF9) (human-mus musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with human-mus …
Tyramine O-sulfate
Experimental
Matched Synonyms: … Tyramine sulfate …
Matched Name: … Tyramine O-sulfate …
Matched Name: … Tyramine O-sulfate …
Zalutumumab
Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.
Investigational
Matched International brands: … HuMax-EGFR ... HuMax-EGFR-2F8 ... HuMax-EGFR, 2F8 …
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. ... Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer. ... Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone ... L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-Nim-benzyl-histidyl-L-leucyl-L-arginyl-L-proline ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Description: … treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Gonadotropin-releasing hormone agonist …
Matched Description: … treatment for children with central precocious puberty (CPP) due to their capacity to reduce LH levels and ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Gonadotropin-releasing hormone agonist …
Eflornithine
Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Synonyms: … 2-(difluoromethyl)ornithine …
Matched Description: … hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells. ... for human African trypanosomiasis. ... [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA …
Matched Categories: … Ornithine Decarboxylase Inhibitors ... Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Description: … hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells. ... for human African trypanosomiasis. ... [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA …
Matched Categories: … Ornithine Decarboxylase Inhibitors ... Agents Against Leishmaniasis and Trypanosomiasis ... Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
3-nitro-L-tyrosine
Experimental
Matched Synonyms: … 3-Nitro-L-tyrosine …
Matched Name: … 3-nitro-L-tyrosine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … 3-nitro-L-tyrosine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tobevibart
Tobevibart is under investigation in clinical trial NCT05612581 (A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection).
Investigational
Matched Synonyms: … Immunoglobulin G1 [238-alanine,332-leucine,334-glutamic acid,430-leucine,436-serine], anti-(hepatitis ... B virus surface antigen) (human monoclonal VIR-3434 γ1-chain), disulfide with human monoclonal VIR-3434 …
Cinrebafusp alfa
Investigational
Matched Synonyms: … (S228>P,F234>A,L235>A) IMMUNOGLOBULIN G4-KAPPA (CHIMERIC HUMAN-MUS MUSCULUS, ANTI-(RECEPTOR TYROSINE-PROTEIN ... IMMUNOGLOBULIN G4 (228-PROLINE, 234-ALANINE, 235-ALANINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR HER2) ... LINKER) FUSION PROTEIN WITH LIPOCALIN 2 (HUMAN MU …
Ciprofloxacin
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493]
The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Fluocinolone Acetonide …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Drug-Related Side Effects and Adverse Reactions ... Ophthalmological and Otological Preparations …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% …
Ndelta-(N'-Sulphodiaminophosphinyl)-L-Ornithine
Experimental
Matched Name: … Ndelta-(N'-Sulphodiaminophosphinyl)-L-Ornithine …
Beludavimab
Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE ... -7832 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOC ... RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL VIR …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dextrothyroxine
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts a broad spectrum...
Approved
Investigational
Matched Synonyms: … O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine …
Matched Description: … Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines ... Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines ... Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Secretin human
Human secretin is a gastrointestinal peptide hormone that regulates secretions in the stomach, pancreas, and liver. The hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 . The main action of secretin is to stimulate the pancreas...
Approved
Matched Synonyms: … Human secretin ... Secretin human ... Secretin (human) …
Matched Name: … Secretin human …
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Secretin human …
Matched Description: … Synthetic human secretin displays equivalent biological activity and properties as naturally-occurring ... , and liver. ... of pancreatic exocrine dysfunction and the diagnosis of gastrinoma, and facilitate the identification …
Matched Salts name: … Secretin human pentahydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Arginine glutamate
Investigational
Matched Synonyms: … Arginine glutamate ... L-Arginine L-glutamate …
Matched Name: … Arginine glutamate …
Matched Categories: … arginine glutamate ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids, Peptides, and Proteins …
Matched Name: … Arginine glutamate …
Matched Categories: … arginine glutamate ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Amino Acids, Peptides, and Proteins …
Displaying drugs 451 - 475 of 1067 in total