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Displaying drugs 4776 - 4800 of 5367 in total

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Iupac: … (2S)-2-(2-oxopyrrolidin-1-yl)butanamide …
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... indexes and a propensity for involvement in drug interactions. ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … LEVETIRACE AL 100 MG/ML ... LEVETIRACETAM GL100 1ML AS ... LEVETIRACE AL 100MG/ML 1ML …

Tiotropium

Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Matched Iupac: … (1R,2R,4S,5S,7R)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0 …
Matched Description: … pulmonary disease (COPD) and asthma. ... Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and ... Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive …
Matched Mixtures name: … FEROMIS 18/12 MCG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 120 ADET ... FEROMIS 9/12 MCG INHALASYON TOZ ICEREN KAPSUL, 120 ADET ... AERODAY 18/12 MCG INHALASYON IÇIN TOZ IÇEREN BLISTER, 60 DOZ …
Matched Categories: … olodaterol and tiotropium bromide ... formoterol and tiotropium bromide ... Aza Compounds ... Drugs that are Mainly Renally Excreted …
Matched Products: … TIODAY CAPSAIR 18 MCG İNHALASYON İÇİN TOZ İÇEREN KAPSÜL, 120 ADET ... SPIRIVA 18 MCG CAPSULES ... BROMURO DE TIOTROPIO 18 µG CÁPSULA …

2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid

Experimental
Matched Name: … 2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid …
Matched Iupac: … (2S)-2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-1,2-oxazol-4-yl]propanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

{[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid

Experimental
Matched Name: … {[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid …
Matched Iupac: … 2R,3R,4R,5R)-6-[(2,2-dihydroxyethyl)(phosphonomethyl)amino]-2,3,4,5-tetrahydroxyhexyl]oxy}phosphonic acid …

6-(2-Oxo-Hexahydro-Thieno[3,4-D]Imidazol-4-Yl)-Hexanoic Acid

Experimental
Matched Name: … 6-(2-Oxo-Hexahydro-Thieno[3,4-D]Imidazol-4-Yl)-Hexanoic Acid …
Matched Iupac: … 6-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]hexanoic acid …

4-{3-CHLORO-4-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-PHENOXY}-BUTYRIC ACID

Experimental
Matched Name: … 4-{3-CHLORO-4-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-PHENOXY}-BUTYRIC ACID …
Matched Iupac: … 4-(3-chloro-4-{[(2,4-dichlorobenzoyl)carbamoyl]amino}phenoxy)butanoic acid …

(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid

Experimental
Matched Name: … (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid …
Matched Iupac: … (2S)-8-{[(tert-butoxy)carbonyl]amino}-2-(1H-indol-3-yl)octanoic acid …

{4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID

Experimental
Matched Name: … {4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID …
Matched Iupac: … N-{4-[2-benzyl-3-methoxy-2-(methoxycarbonyl)-3-oxopropyl]phenyl}sulfamic acid …

3-fluoro-6-(4-fluorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid

Experimental
Matched Name: … 3-fluoro-6-(4-fluorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid …
Matched Iupac: … (2Z,4E)-3-fluoro-6-(4-fluorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid …

5-(4-CYANOPHENYL)-3-{[(2-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID

Experimental
Matched Name: … 5-(4-CYANOPHENYL)-3-{[(2-METHYLPHENYL)SULFONYL]AMINO}THIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 5-(4-cyanophenyl)-3-(2-methylbenzenesulfonamido)thiophene-2-carboxylic acid …

{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid

Experimental
Matched Name: … {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid …
Matched Iupac: … 2-{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid …

N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID

Experimental
Matched Name: … N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID …
Matched Iupac: … 5-[methyl({4-[(1E)-2-(4-nitrophenyl)ethenyl]phenyl})amino]pentanoic acid …

(2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID

Experimental
Matched Name: … (2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACID …
Matched Iupac: … (2S,3S)-3-formyl-2-[(4-nitrobenzenesulfonamido)methyl]pentanoic acid …

8-Hydroxy-2-oxa-bicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid

Experimental
Matched Name: … 8-Hydroxy-2-oxa-bicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid …
Matched Iupac: … (1R,3S,5S,8R)-8-hydroxy-2-oxabicyclo[3.3.1]non-6-ene-3,5-dicarboxylic acid …

Norclobazam

Investigational
Matched Synonyms: … 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 8-chloro-1-phenyl-7-chloro-5-phenyl-1,2,4,5-tetrahydro-3h-1,5 …
Matched Iupac: … 8-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …

Felodipine

Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction. Felodipine is the most potent CCB...
Approved
Investigational
Matched Synonyms: … 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ... (±)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate ... 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b. ... Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. ... influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ramipril and felodipine ... metoprolol and felodipine ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers …
Matched Products: … Apo-felodipine ... FELODIPIN AL 5MG RETARD ... FELODIPIN ABZ 5MG RETARD …

Amotosalen

Investigational
Matched Synonyms: … 7h-furo(3,2-g)(1)benzopyran-7-one, 3-((2-aminoethoxy)methyl)-2,5,9-trimethyl- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Methotrimeprazine

A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Synonyms: … (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine ... (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine …
Matched Iupac: … [(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … LEVOMEPROMAZIN-NEURAX 100 ... SINOGAN® 100 MG TABLETAS. ... Nozinan 100 mg - Filmtabletten …

Forodesine

Forodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic leukemia and cutaneous T-cell lymphoma. Additional preliminary findings support its use for the management of some B-cell malignancies.
Investigational
Matched Synonyms: … 1,4-Dideoxy-4-aza-1-(S)-(9-deazahypoxanthin-9-yl)-D-ribitol ... (1S)-1,4-dideoxy-4-imino-(9-deazahypoxanthin-9-yl)-D-ribitol …
Matched Description: … leukemia and cutaneous T-cell lymphoma. ... in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic ... Forodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity …
Matched Salts cas: … 284490-13-7 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Heterocyclic Compounds, 1-Ring …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino …
Matched Description: … Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs ... [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations ... ATP binding activity to EGFR and result in poor prognosis for late-stage disease. …
Matched Salts cas: … 1421373-66-1 …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring ... Acids, Acyclic ... Carboxylic Acids ... P-glycoprotein substrates with a Narrow Therapeutic Index …

BN104

Investigational
Matched Synonyms: … ,3aR,6aS)-octahydrocyclopenta[c]pyrrol-1-yl)methanone ... -(4-cyclopropylpyrimidin-5-yl)-4-fluorophenoxy)-1,2,4-triazin-5-yl)-2,7-diazaspiro[3.5]nonan-7-yl)((1S …

(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE

Experimental
Matched Name: … (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL …
Matched Iupac: … (1S,2R,5S)-5-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-2-(2,4,5-trifluorophenyl ... )cyclohexan-1-amine …

1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine

Experimental
Matched Name: … 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine …
Matched Iupac: … 1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine …

1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)PYRIMIDINE-2,4(1H,3H)-DIONE

Experimental
Matched Name: … 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)PYRIMIDINE-2,4(1H,3H)-DIONE …
Matched Iupac: … 5-{[3-(benzyloxy)phenyl]methyl}-1-[(2-hydroxyethoxy)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …

1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE

Experimental
Matched Name: … 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE …
Matched Iupac: … 1-({2-[2-(4-chlorophenyl)ethyl]-1,3-dioxolan-2-yl}methyl)-1H-imidazole …
Displaying drugs 4776 - 4800 of 5367 in total