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Displaying drugs 4801 - 4825 of 9692 in total

Human blood group H type 1 trisaccharide

Experimental
Matched Synonyms: … αLFuc(1-2)βDGal(1-3)βDGlcNAc ... α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc ... alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc …
Matched Iupac: … -6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-2,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide ... N-[(2R,3R,4R,5S,6R)-4-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy …

Chlorfenson

Chlorfenson is developed by Moberg Derma for the treatment of onychomycosis (nail fungus) as the primary indication.
Investigational

Efzofitimod

Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …

(2S)-1-AMINO-3-[(5-NITROQUINOLIN-8-YL)AMINO]PROPAN-2-OL

Experimental
Matched Name: … (2S)-1-AMINO-3-[(5-NITROQUINOLIN-8-YL)AMINO]PROPAN-2-OL …
Matched Iupac: … (2S)-1-amino-3-[(5-nitroquinolin-8-yl)amino]propan-2-ol …

Resveratrol

Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet...
Investigational
Matched Synonyms: … (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol ... 5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol ... 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol …
Matched Iupac: … 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol …

Myricetin

Experimental
Matched Synonyms: … 3,3',4,4',5',7-Hexahydro-2-phenyl-4H-chromen-4-one ... 3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one …
Matched Iupac: … 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Xaluritamig

Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Investigational
Matched Synonyms: … STEAP1) (human-Mus musculus clone 2F3.013 N67Q γ1-chain) fusion protein with peptide linker (GGGGS)2 …

Methylpropylpropanediol dinitrate

Experimental
Matched Synonyms: … 2-methyl-2-propylpropane-1,3-diyl dinitrate …
Matched Iupac: … 2-methyl-1-(nitrooxy)-2-[(nitrooxy)methyl]pentane …

Temafloxacin

Temafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class. It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three deaths.
Withdrawn
Matched Iupac: … 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Diloxanide

Diloxanide (as Diloxanide furoate) is an anti-protozoal drug used in the treatment of Entamoeba histolytica and some other protozoal infections. Although it is not currently approved for use in the United States, it was approved by a CDC study in the treatment of 4,371 cases of Entamoeba histolytica from 1977...
Experimental

2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE

Experimental
Matched Name: … 2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE …
Matched Iupac: … 2-(2,6-difluorophenoxy)-N-(2-fluorophenyl)-9-(propan-2-yl)-9H-purin-8-amine …

N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-{6-[(3-methylbutyl)amino]-9H-purin-9-yl}oxolan-2-yl]methoxy}phosphonic …

Dipyrocetyl

Experimental
Matched Iupac: … 2,3-bis(acetyloxy)benzoic acid …

LY231514 tetra glu

Experimental
Matched Iupac: … 2-[(4S)-4-[(4S)-4-[(4S)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido …

XV638

Experimental
Matched Iupac: … 3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-2-oxo-3-({3-[(1,3-thiazol-2-yl)carbamoyl]phenyl}methyl)- ... 1,3-diazepan-1-yl]methyl}-N-(1,3-thiazol-2-yl)benzamide …

CP-601927

CP-601,927 has been used in trials studying the basic science and treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … (1S,8R)-4-(trifluoromethyl)-10-azatricyclo[6.3.1.0^{2,7}]dodeca-2(7),3,5-triene …

BI-671800

Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.
Investigational
Matched Iupac: … 2-[4,6-bis(dimethylamino)-2-({4-[4-(trifluoromethyl)benzamido]phenyl}methyl)pyrimidin-5-yl]acetic acid …

CP-609754

LNK 754 has been investigated in Mild Alzheimer's Disease.
Investigational
Matched Iupac: … 6-[(R)-(4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-ethynylphenyl)-1-methyl-1,2-dihydroquinolin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

αAβ–Gas6

αAβ–Gas6 is a chimeric fusion protein being investigated in preclinical studies as an immunotherapeutic agent for Alzheimer's disease (AD). It is made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is...
Experimental
Matched Description: … targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 …

4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID

Experimental
Matched Name: … 4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID …
Matched Iupac: … (3Z)-4-(2-methoxyphenyl)-2-oxobut-3-enoic acid …

Irsenontrine

Irsenontrine is under investigation in clinical trial NCT03467152 (Study to Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia With Lewy Bodies).
Investigational
Matched Synonyms: … 7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-((3s)-tetrahydrofuran-3-yl)-1,5-dihydro-4h-pyrazolo(4,3-c)quinolin ... -3-furanyl)- ... 4h-pyrazolo(4,3-c)quinolin-4-one, 1,5-dihydro-7-(2-methoxy-3,5-dimethyl-4- pyridinyl)-1-((3s)-tetrahydro …

[(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron

Experimental
Matched Name: … [(1R)-1-acetamido-2-(4-chlorophenyl)ethyl]-[(2S)-2-amino-3-hydroxy-3-oxo-propoxy]-dihydroxy-boron …
Matched Iupac: … [(2S)-2-amino-2-carboxyethoxy][(1R)-2-(4-chlorophenyl)-1-acetamidoethyl]dihydroxyboranuide …

N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine

Experimental
Matched Name: … N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine …
Matched Iupac: … N1-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine …

Laninamivir

Laninamivir has been used in trials studying the treatment of Influenza.
Investigational
Matched Iupac: … (2R,3R,4S)-4-carbamimidamido-2-[(1R,2R)-2,3-dihydroxy-1-methoxypropyl]-3-acetamido-3,4-dihydro-2H-pyran ... -6-carboxylic acid …

TRC150094

TRC150094 is under investigation in clinical trial NCT03254446 (Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension).
Investigational
Matched Iupac: … 3-{4-[(7-hydroxy-6-methyl-2,3-dihydro-1H-inden-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}propanoic acid …
Displaying drugs 4801 - 4825 of 9692 in total